Anthony De Tomaso

Web Site Links

• De Tomaso Lab

Research Interests

We are investigating several interrelated phenomena in a primitive chordate, the ascidian Botryllus schlosseri. The lab is located at Stanford’s Hopkins Marine Station on the Monterey Peninsula, where we are studying: 1) allorecognition and the evolutionary origins of different components of the vertebrate immune system; 2) pluripotent, parasitic stem cells; 3) the molecular mechanisms which underlie complete asexual regeneration in this organism.

Publications

• A conserved role of the VEGF pathway in angiogenesis of an ectodermally-derived vasculature. Tiozzo S, Voskoboynik A, Brown FD, De Tomaso AW. Dev Biol. 2008; 315 (1): 243-55
• Striving for normality: whole body regeneration through a series of abnormal generations. Voskoboynik A, Simon-Blecher N, Soen Y, Rinkevich B, De Tomaso AW, Ishizuka KJ, Weissman IL. FASEB J. 2007; 21 (7): 1335-44
• Allorecognition polymorphism versus parasitic stem cells. De Tomaso AW, Trends Genet. 2006; 22 (9): 485-90
• fester, A candidate allorecognition receptor from a primitive chordate. Nyholm SV, Passegue E, Ludington WB, Voskoboynik A, Mitchel K, Weissman IL, De Tomaso AW. Immunity. 2006; 25 (1): 163-73
• Predatory stem cells in the non-zebrafish chordate, Botryllus schlosseri. Laird DJ, De Tomaso AW. Zebrafish. 2005; 1 (4): 357-61