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Magali FontaineAcademic Appointments
Appointment
Organization
Assistant Professor - Med Center Line
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Honors & Awards
Title
Organization
Date(s)
M.D. Summa cum laude
University of Paris V
10-31-1989
Administrative Appointments
Title
Organization
Start Year
End Year
Assistant Director of Blood Services
Stanford Blood Center
2004
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Associate Director
Transfusion Service
2004
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Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
M.D.
University of Paris-V
Medicine
1989
Ph.D.
University of Illinois
Islet Transplantation
2000
Research Interests
Our interest lies at the frontier of Transfusion Medicine by developing and optimizing new cellular therapies such as islet transplantation for patients with Type 1 Diabetes.
Our primary focus has been to treat IDDM-I with pancreatic islet-cell replacement therapy instead of insulin-injections. We have studied pancreatic islet preservation and function after their isolation from the pancreas and we have developed new conditions of isolation to optimize islet cell function for transplantation. This new therapeutic approach still needs refinements, which we are working on, to prevent long term islet-graft failure from recurrence of autoimmunity, rejection, and/or insulin resistance.
Our primary focus has been to treat IDDM-I with pancreatic islet-cell replacement therapy instead of insulin-injections. We have studied pancreatic islet preservation and function after their isolation from the pancreas and we have developed new conditions of isolation to optimize islet cell function for transplantation. This new therapeutic approach still needs refinements, which we are working on, to prevent long term islet-graft failure from recurrence of autoimmunity, rejection, and/or insulin resistance.
Publications
- Kvezereli M, Vallentin A, Mochly-Rosen D, Busque S, Fontaine MJ "Islet cell survival during isolation improved through protein kinase C epsilon activation." Transplant Proc 2008; 40: 2: 375-8 More »
- Burtelow M, Riley E, Druzin M, Fontaine M, Viele M, Goodnough LT "How we treat: management of life-threatening primary postpartum hemorrhage with a standardized massive transfusion protocol." Transfusion 2007; 47: 9: 1564-72 More »
- Wong W, Merker JD, Nguyen C, Berquist W, Jeng M, Viele M, Glader B, Fontaine MJ "Cold agglutinin syndrome in pediatric liver transplant recipients." Pediatr Transplant 2007; 11: 8: 931-6 More »
- Karnik SK, Chen H, McLean GW, Heit JJ, Gu X, Zhang AY, Fontaine M, Yen MH, Kim SK "Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus." Science 2007; 318: 5851: 806-9 More »
- Boyd SD, Stenard F, Lee DK, Goodnough LT, Esquivel CO, Fontaine MJ "Alloimmunization to red blood cell antigens affects clinical outcomes in liver transplant patients." Liver Transpl 2007; 13: 12: 1654-61 More »
11 publications: view full list
