{"result":[{"lastName":"Pollack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","displayName":"Jonathan Pollack","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/hrp/researcher/Jonathan_Pollack","researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/hrp/researcher/Amato_Giaccia","researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells."},{"lastName":"Higgins","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4038&type=small&showNoImage","displayName":"John Higgins","firstName":"John","href":"http://med.stanford.edu/profiles/hrp/researcher/John_Higgins","researchInterest":"I work as a diagnostic surgical pathologist doing tissue and cDNA microarray-based translational research in renal neoplasia and medical renal disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology."},{"lastName":"Diehn","clinicalFocus":[],"appointments":[{"appointment":"Acting Assistant Professor,Radiation Oncology - Radiation Therapy"}],"primaryAppointment":"Acting Assistant Professor,Radiation Oncology - Radiation Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9248&type=small&showNoImage","displayName":"Maximilian Diehn, M.D., Ph.D.","firstName":"Maximilian","href":"http://med.stanford.edu/profiles/hrp/researcher/Maximilian_Diehn","researchInterest":"My lab focuses on cancer stem cell biology and its implications for cancer therapy. We are interested in developing a deeper molecular understanding of cancer stem cells, including identifying pathways and genes important for proliferation and self renewal. We also study these processes in normal adult stem cells in order to identify differences that could be exploited therapeutically. The goal of our studies is the development of novel therapeutic strategies for eliminating cancer stem cells."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/hrp/researcher/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Alizadeh","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9558&type=small&showNoImage","displayName":"Ash A. Alizadeh, MD/PhD","firstName":"Arash","href":"http://med.stanford.edu/profiles/hrp/researcher/Arash_Alizadeh","researchInterest":"My research is focused on attaining a better understanding of the initiation, maintenance, and progression of lymphoid tumors, and their response to immunochemotherapy toward improving current treatment strategies.  \r\n\r\nIn this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.  I hope to apply this knowledge towards the design of clinical trials in the treatment of patients with lymphoma, leukemia, and myeloma."},{"lastName":"Van de Rijn","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4008&type=small&showNoImage","displayName":"Matt Van de Rijn","firstName":"Matt","href":"http://med.stanford.edu/profiles/hrp/researcher/Matt_Van de Rijn","researchInterest":"Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis."},{"lastName":"Koong","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Colorectal Cancer - Radiation Oncology"},{"focus":"Esophageal Cancer"},{"focus":"Esophageal Cancer - Radiation Oncology"},{"focus":"Liver Cancer"},{"focus":"Liver Cancer - Radiation Oncology"},{"focus":"Pancreatic Cancer "},{"focus":"Pancreatic Cancer - Radiation Oncology"},{"focus":"Radiation Oncology"},{"focus":"Rectal Cancer "},{"focus":"Rectal Cancer - Radiation Oncology"},{"focus":"Stomach Cancer "},{"focus":"Stomach Cancer - Radiation Oncology"}],"appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4729&type=small&showNoImage","displayName":"Albert Koong","firstName":"Albert","href":"http://med.stanford.edu/profiles/hrp/researcher/Albert_Koong","researchInterest":"The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic radiosurgery for GI maligancies"},{"lastName":"Natkunam","clinicalFocus":[{"focus":"Hematopathology"},{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5929&type=small&showNoImage","displayName":"Yasodha Natkunam, M.D., Ph.D","firstName":"Yasodha","href":"http://med.stanford.edu/profiles/hrp/researcher/Yasodha_Natkunam","researchInterest":"My research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia."},{"lastName":"Sahoo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10888&type=small&showNoImage","displayName":"Debashis Sahoo","firstName":"Debashis","href":"http://med.stanford.edu/profiles/hrp/researcher/Debashis_Sahoo","researchInterest":""},{"lastName":"Brooks","clinicalFocus":[{"focus":"Male Cancers - Prostate "},{"focus":"Prostate Cancer"},{"focus":"Nerve-sparing radical prostatectomy"},{"focus":"Prostate Cancer - Urologic Oncology"},{"focus":"Urologic Cancers"},{"focus":"Urologic Cancers - Urologic Oncology"},{"focus":"Urology"}],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6178&type=small&showNoImage","displayName":"James D. Brooks","firstName":"James","href":"http://med.stanford.edu/profiles/hrp/researcher/James_Brooks","researchInterest":"We have used comprehensive gene expression profiling for 2 translational research objectives: 1) to understand the mechanisms of action of candidate prostate cancer preventive agents and develop biomarkers that we can use to evaluate response; and 2) to identify diagnostic and prognostic markers for prostate, kidney, testicular and bladder cancers."},{"lastName":"Denko","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","displayName":"Nicholas Denko","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/hrp/researcher/Nicholas_Denko","researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes."},{"lastName":"Whittemore","clinicalFocus":[],"appointments":[{"appointment":"Professor,Health Research & Policy - Epidemiology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Health Research & Policy - Epidemiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4482&type=small&showNoImage","displayName":"Alice S Whittemore","firstName":"Alice","href":"http://med.stanford.edu/profiles/hrp/researcher/Alice_Whittemore","researchInterest":"Cancers of the prostate, breast and ovary account for a major proportion of new cancer cases and cancer deaths in the U.S. each year. Our recent research focus has been on developing improved statistical methods for the design and conduct of studies involving hereditary predisposition and modifiable lifestyle characteristics in the etiologies of site-specific cancers."},{"lastName":"Le","clinicalFocus":[{"focus":"Head and Neck Cancers"},{"focus":"Head and Neck Cancers - Radiation Oncology"},{"focus":"Larynx Cancer "},{"focus":"Larynx Cancer - Radiation Oncology"},{"focus":"Lung Cancer - Radiation Oncology"},{"focus":"Oral Cavity Cancer  "},{"focus":"Oral Cavity Cancer - Radiation Oncology"},{"focus":"Radiation Oncology"},{"focus":"Salivary Gland Tumors"},{"focus":"Salivary Gland Tumors - Radiation Oncology"},{"focus":"Sarcomas - Soft Tissue "},{"focus":"Sarcomas - Soft Tissue - Radiation Oncology"},{"focus":"Skull Base Tumors "},{"focus":"Skull Base Tumors - Radiation Oncology"}],"appointments":[{"appointment":"Professor - Med Center Line,Radiation Oncology - Radiation Therapy"},{"appointment":"Professor - Med Center Line (By courtesy),Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Radiation Oncology - Radiation Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4003&type=small&showNoImage","displayName":"Quynh-Thu Le","firstName":"Quynh-Thu","href":"http://med.stanford.edu/profiles/hrp/researcher/Quynh-Thu_Le","researchInterest":"My laboratory research interest focusses on the identification of serum markers for tumor hypoxia and for prognosis in patients with head and neck or lung cancers. I am also conducting a number of clinical trials specifically in patients with these tumors."},{"lastName":"Arber","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","displayName":"Daniel A. Arber, M.D.","firstName":"Daniel","href":"http://med.stanford.edu/profiles/hrp/researcher/Daniel_Arber","researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors."},{"lastName":"Butte","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Cancer Biology"},{"appointment":"Assistant Professor,Medicine"},{"appointment":"Assistant Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Pediatrics - Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6603&type=small&showNoImage","displayName":"Atul Butte","firstName":"Atul","href":"http://med.stanford.edu/profiles/hrp/researcher/Atul_Butte","researchInterest":"Translational bioinformatics has been defined as the development of analytic\r\nmethods to help transform increasingly voluminous genomic and biological data into diagnostics and therapeutics for the clinician.  The long-term research goal of the Butte Lab is to develop translational bioinformatics methods to reason over many available genome-scale measurement and experimental modalities, and apply these methods to study complex disorders in genomic medicine, especially obesity and diabetes."},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/hrp/researcher/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Warnke","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3786&type=small&showNoImage","displayName":"Roger Warnke","firstName":"Roger","href":"http://med.stanford.edu/profiles/hrp/researcher/Roger_Warnke","researchInterest":"The research in my laboratory involves the application of monoclonal and polyclonal antibodies and a variety of immunohistochemical methods to study human B-cell, T-cell, accessory cell and related neoplasms."},{"lastName":"Plevritis","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4724&type=small&showNoImage","displayName":"Sylvia K. Plevritis, PhD","firstName":"Sylvia","href":"http://med.stanford.edu/profiles/hrp/researcher/Sylvia_Plevritis","researchInterest":"My research program focuses on computational modeling of cancer biology and cancer outcomes. We develop stochastic models of the natural history of cancer based on clinical research data.   We estimate population-level outcomes under differing screening and treatment interventions.  We also analyze genomic and proteomic cancer data in order to identify molecular networks that are perturbed in cancer initiation and progression and relate these perturbations to patient outcomes."},{"lastName":"Ford","clinicalFocus":[{"focus":"Cancer Genetics"},{"focus":"Gastrointestinal Cancers - Genetics"},{"focus":"Gastrointestinal Cancers - Medical Oncology"},{"focus":"Breast Cancer - Genetics"},{"focus":"Ovarian Cancer - Genetics"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Associate Professor (By courtesy),Pediatrics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4066&type=small&showNoImage","displayName":"James Ford","firstName":"James","href":"http://med.stanford.edu/profiles/hrp/researcher/James_Ford","researchInterest":"Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA\u000bdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer."},{"lastName":"Kong","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4718&type=small&showNoImage","displayName":"Christina Kong","firstName":"Christina","href":"http://med.stanford.edu/profiles/hrp/researcher/Christina_Kong","researchInterest":"Improving the accuracy of cytologic diagnosis through the use of ancillary techniques on cytology specimens.  \r\n\r\nEvaluating various immunohistochemical markers as potential indicators of prognosis in head and neck squamous cell carcinomas."},{"lastName":"Sherlock","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5864&type=small&showNoImage","displayName":"Gavin Sherlock","firstName":"Gavin","href":"http://med.stanford.edu/profiles/hrp/researcher/Gavin_Sherlock","researchInterest":"Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species; genome database for Candida albicans; genome database for Aspergilli; the Stanford Microarray Database; The Tuberculosis Database; bioinformatics tools for analysing expression data."},{"lastName":"Longacre","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6082&type=small&showNoImage","displayName":"Teri A Longacre","firstName":"Teri","href":"http://med.stanford.edu/profiles/hrp/researcher/Teri_Longacre","researchInterest":"Gynecological, breast and gastrointestinal pathology with major emphasis on ovarian cancer and ovarian tumors of low malignant potential. Pathology of familial and hereditary breast-ovarian-GI cancer."},{"lastName":"Spin","clinicalFocus":[{"focus":"Aortic Disease"},{"focus":"Marfan Syndrome and Aortic Disorders"},{"focus":"Cardiovascular Disease"}],"appointments":[{"appointment":"Instructor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6448&type=small&showNoImage","displayName":"Joshua M. Spin","firstName":"Joshua","href":"http://med.stanford.edu/profiles/hrp/researcher/Joshua_Spin","researchInterest":"Dr. Spin began his research career studying the structural biology of low density lipoprotein, and has been augmenting his skills with intensive training in molecular biology techniques, particularly those involving high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development and vascular disease."},{"lastName":"John","clinicalFocus":[],"appointments":[{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Member,Cancer Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7425&type=small&showNoImage","displayName":"Esther M. John","firstName":"Esther","href":"http://med.stanford.edu/profiles/hrp/researcher/Esther_John","researchInterest":"Etiology of breast, prostate and ovarian cancer; cancer in Hispanics and African-Americans; migration and acculturation in Hispanics; modifiable lifestyle factors (vitamin D, physical activity, body size, heterocyclic amines, occupational exposures); genetic susceptibility; gene-environment interactions"}]}