Robert Tibshirani

Publication Details

• A tail strength measure for assessing the overall univariate significance in a dataset.

  Taylor J, Tibshirani R. Biostatistics. 2006; 7 (2): 167-81

  We propose an overall measure of significance for a set of hypothesis tests. The 'tail strength' is a simple function of the p-values computed for each of the tests. This measure is useful, for example, in assessing the overall univariate strength of a large set of features in microarray and other genomic and biomedical studies. It also has a simple relationship to the false discovery rate of the collection of tests. We derive the asymptotic distribution of the tail strength measure, and illustrate its use on a number of real datasets.

  PubMedID: 16332926