{"result":[{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Shah","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Biomedical Informatics Research"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Biomedical Informatics Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19142&type=small&showNoImage","displayName":"Nigam H. Shah, MBBS, PhD","firstName":"Nigam","href":"http://med.stanford.edu/profiles/Nigam_Shah","researchInterest":"My research group studies ontology-based approaches to annotate, index, integrate and analyze unstructured information available in biomedicine for the purpose of enabling data-driven analytics in medicine and health care."},{"lastName":"Fraser","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15112&type=small&showNoImage","displayName":"Hunter Fraser","firstName":"Hunter","href":"http://med.stanford.edu/profiles/Hunter_Fraser","researchInterest":""},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23896&type=small&showNoImage","displayName":"Jingjing Li","firstName":"Jingjing","href":"http://med.stanford.edu/profiles/Jingjing_Li","researchInterest":""},{"lastName":"Roskin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21093&type=small&showNoImage","displayName":"Krishna Roskin","firstName":"Krishna","href":"http://med.stanford.edu/profiles/Krishna_Roskin","researchInterest":""},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/Arend_Sidow","researchInterest":"We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Gherardini","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35679&type=small&showNoImage","displayName":"Pier Federico Gherardini","firstName":"Pier Federico","href":"http://med.stanford.edu/profiles/Pier Federico_Gherardini","researchInterest":""},{"lastName":"Sherlock","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5864&type=small&showNoImage","displayName":"Gavin Sherlock","firstName":"Gavin","href":"http://med.stanford.edu/profiles/Gavin_Sherlock","researchInterest":"Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species"},{"lastName":"Musen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Biomedical Informatics Research"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Biomedical Informatics Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4164&type=small&showNoImage","displayName":"Mark Musen","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Musen","researchInterest":"My laboratory investigates the use of distributed, component-based software architectures to build intelligent computer systems. Emphasis is on knowledge modeling and knowledge reuse. Our goals are to enhance methodologies that faculitate building and maintaining electronic knowledge bases that can drive useful biomedical computer systems. Current work concentrates on automation of clinical practice guidelines and clinical-trial protocols, and surveillance for potential episodes of bioterrorism."},{"lastName":"Montgomery","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor,Genetics"},{"appointment":"Assistant Professor (By courtesy),Computer Science"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23650&type=small&showNoImage","displayName":"Stephen B. Montgomery","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Montgomery","researchInterest":"We focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches.  See our website at http://montgomerylab.stanford.edu/"},{"lastName":"Araya","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23129&type=small&showNoImage","displayName":"Carlos L. Araya","firstName":"Carlos","href":"http://med.stanford.edu/profiles/Carlos_Araya","researchInterest":""},{"lastName":"Skotheim","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":" (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10452&type=small&showNoImage","displayName":"Jan Skotheim","firstName":"Jan","href":"http://med.stanford.edu/profiles/Jan_Skotheim","researchInterest":"A central aim of the burgeoning field of systems biology is to understand the principles governing genetic control networks. I believe finding the principles underlying genetic circuits will occur through detailed studies and then comparisons of several natural systems. Due to its extensive development as an experimental system, our favorite model, the budding yeast cell cycle, is poised to become central to this enterprise."},{"lastName":"Mallick","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18938&type=small&showNoImage","displayName":"Parag Mallick","firstName":"Parag","href":"http://med.stanford.edu/profiles/Parag_Mallick","researchInterest":"Our research centers on developing and applying  proteomics and systems biology approaches to quantitatively describe organisms' physiologic states towards the goal of enabling personalized, predictive medicine.  As part of this effort we are trying to characterize the diverse states of cells (using proteomic and transcriptomic methods) and how signals describing those states are propagated from molecular and cellular length scales to tumor and organismic length scales."},{"lastName":"Rubin","clinicalFocus":[{"focus":"Diagnostic Radiology"},{"focus":"Radiology"},{"focus":"Imaging informatics"},{"focus":"Biomedical informatics"},{"focus":"Quantitative Imaging"}],"appointments":[{"appointment":"Assistant Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Assistant Professor,Medicine - Biomedical Informatics Research"}],"primaryAppointment":"Assistant Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10416&type=small&showNoImage","displayName":"Daniel Rubin","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Rubin","researchInterest":"My research interest is imaging informatics--ways computers can work with images to leverage their rich information content and to help physicians use images to guide personalized care. Work in our lab thus lies at the intersection of biomedical informatics and imaging science."},{"lastName":"Boyle","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17416&type=small&showNoImage","displayName":"Alan Boyle","firstName":"Alan","href":"http://med.stanford.edu/profiles/Alan_Boyle","researchInterest":""},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Das","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5918&type=small&showNoImage","displayName":"Amar K. Das","firstName":"Amarendra","href":"http://med.stanford.edu/profiles/Amarendra_Das","researchInterest":"My research focuses on informatics methods to study outcomes and biomarkers in longitudinal data sets."},{"lastName":"Collins","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10605&type=small&showNoImage","displayName":"Sean Collins","firstName":"Sean","href":"http://med.stanford.edu/profiles/Sean_Collins","researchInterest":""},{"lastName":"Wei","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Biochemistry - Stanford Genome Technology Center"}],"primaryAppointment":"Basic Life Science Research Associate,Biochemistry - Stanford Genome Technology Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29094&type=small&showNoImage","displayName":"Wu Wei","firstName":"Wu","href":"http://med.stanford.edu/profiles/Wu_Wei","researchInterest":""},{"lastName":"Frommer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6305&type=small&showNoImage","displayName":"Wolf B. Frommer","firstName":"Wolf","href":"http://med.stanford.edu/profiles/Wolf_Frommer","researchInterest":"Watching cells at work \r\nFocus: Transport / signaling across the plasma membrane (sugars, amino acids). \r\nTools: FRET-based nanosensors for metabolite imaging (with subcellular resolution) in living organisms using confocal fluorescence microscopy and HTS; Sensor optimization by computational design; RNAi to modify cellular functions.\r\nGoals: Identify unknown sugar effluxers from liver/plant cells; study regulatory networks. \r\nModel systems: liver, neuronal, plant cell cultures, Arabidopsis, yeast"}]}