Genetics

Department: Genetics

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    • Postdoctoral Research fellow
    • Postdoctoral Research fellow
    Research Interest

    My overarching goal is to identify molecular mechanisms by which age-associated diseases arise to develop pharmacological or stem cell-based interventions that prevent or cure those diseases. My particular emphasis is on mammalian brain aging and neurodegenerative diseases. My current research focuses on the molecular and cellular mechanisms that govern the age-associated functional decline of adult neural stem cells. In the nervous system, the number and function of adult neural stem cells..

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    • Postdoctoral Research fellow
    Research Interest

    I specialize in Bioinformatics. Had worked on post-transcriptional regulation (microRNAs) for 5 years during PhD under the mentor ship of Prof. Samir Brahmachari at IGIB, India. Now focusing on building gene regulatory networks using high-throughput genomics and proteomics datasets. Analysis of genomic variations is also a research focus. Currently working with Mike Snyder.

    • Postdoctoral Research fellow
    • Postdoctoral Research fellow
    • Postdoctoral Research fellow

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    • Postdoctoral Research fellow
    • Postdoctoral Research fellow
    • Postdoctoral Research fellow
    • Postdoctoral Research fellow
    Research Interest

    My work is aimed at understanding cell signaling mechanisms that regulate the phagocytosis pathway in retinal pigment epithelium (RPE) cells. Loss of RPE phagocytic function leads to severe retinal degeneration in mouse models and retinitis pigmentosa in humans. Understanding these pathways will provide valuable insight into further treatments for retinal degenerative diseases.

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    • Postdoctoral Research fellow
    Research Interest

    Stem cell function requires both the establishment and maintenance of particular epigenetic states. Perturbation of the epigenetic status of stem cells may compromise both self-renewal and multipotency. Work from our lab has identified the Forkhead family transcription factor, FoxO3, as a regulator of adult neural stem cell (NSCs) quiescence, which prevents the depletion of this population of cells. Along with recent evidence that Forkhead family members act as ‘pioneer factors’ in the opening ..

    • Postdoctoral Research fellow
    • Postdoctoral Research fellow

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