Tianyun Liu
Academic Appointments
- Engr Res Assoc, Genetics
Key Documents
Contact Information
- Contact Information
Supervisors Russ Altman
Professional Overview
Professional Interests
My research interests lie in drug repurposing and personalization through structural biology and systems biology approaches. In particular, my focus is on relating the genetic features of patients to acquired genes and pathway dependencies and identifying small-molecule drugs that target them.
Education and Certifications
| B.S.: | Peking University, China, Biochemistry and Molecular Biology (1997) |
| M.S.: | Peking University, China, Biochemistry and Molecular Biology (2000) |
| Ph.D.: | University of Washington, Seattle, Computational Biology (2005) |
Publications
- Using multiple microenvironments to find similar ligand-binding sites: application to kinase inhibitor binding. PLoS Comput Biol. 2011; (12): e1002326
- Identification of recurring protein structure microenvironments and discovery of novel functional sites around CYS residues. BMC Struct Biol. 2010: 4
- A novel method for predicting and using distance constraints of high accuracy for refining protein structure prediction. Proteins. 2009; (1): 220-34
- Predicting drug side-effects by chemical systems biology. Genome Biol. 2009; (9): 238
- Prediction of calcium-binding sites by combining loop-modeling with machine learning. BMC Struct Biol. 2009: 72
- Improving the accuracy of template-based predictions by mixing and matching between initial models. BMC Struct Biol. 2008: 24
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