{"result":[{"lastName":"Boucard","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9569&type=small&showNoImage","displayName":"Antony Boucard","firstName":"Antony","href":"http://med.stanford.edu/profiles/Antony_Boucard","researchInterest":""},{"lastName":"Lotspeich","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Clinical Professor,Psychiatry & Behavioral Science - Child Psychiatry"}],"primaryAppointment":"Clinical Professor,Psychiatry & Behavioral Science - Child Psychiatry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4733&type=small&showNoImage","displayName":"Linda Lotspeich","firstName":"Linda","href":"http://med.stanford.edu/profiles/Linda_Lotspeich","researchInterest":""},{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Hardan","clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Child and Adolescent Psychiatry"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Psychiatry & Behavioral Science - Child Psychiatry"}],"primaryAppointment":"Associate Professor - Med Center Line,Psychiatry & Behavioral Science - Child Psychiatry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7312&type=small&showNoImage","displayName":"Antonio Hardan","firstName":"Antonio","href":"http://med.stanford.edu/profiles/Antonio_Hardan","researchInterest":"The neurobiology of autism\r\nNeuroimaging in individuals with autism\r\nPsychopharmacological treatment of children with autism and/or intellectual disabilities\r\nNeurobiology and psychopharmacology of schizophrenia and early onset psychotic disorders"},{"lastName":"Feinstein","clinicalFocus":[{"focus":"Child Psychiatry"},{"focus":"Psychiatry, Child and Adolescent"}],"appointments":[{"appointment":"Professor - Med Center Line,Psychiatry & Behavioral Science - Child Psychiatry"},{"appointment":"Professor - Med Center Line (By courtesy),Pediatrics"}],"primaryAppointment":"Professor - Med Center Line,Psychiatry & Behavioral Science - Child Psychiatry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4412&type=small&showNoImage","displayName":"Carl Feinstein","firstName":"Carl","href":"http://med.stanford.edu/profiles/Carl_Feinstein","researchInterest":"Autism and Asperger's Disorder.\r\n\r\nGenetically-based neurodevelopmental disorder, including Velocardiofacial Syndrome, Smith-Magenis Syndrome, Williams Syndrome, and Fragile X Syndrome.\r\n\r\nIntellectual Disability (mental retardation)  and psychiatric disorders.\r\n\r\nDevelopmental Language Disorder and Learning Disabilities.\r\n\r\nSensory impairment in children, including visual and hearing impairment.\r\n\r\nPsychiatric aspects of medical illness and disability in children."},{"lastName":"Newell","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8821&type=small&showNoImage","displayName":"Evan Newell","firstName":"Evan","href":"http://med.stanford.edu/profiles/Evan_Newell","researchInterest":""},{"lastName":"Riley","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9852&type=small&showNoImage","displayName":"Brigit Erin RILEY","firstName":"Brigit","href":"http://med.stanford.edu/profiles/Brigit_Riley","researchInterest":""},{"lastName":"Kaiser","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10008&type=small&showNoImage","displayName":"Stephen Kaiser","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Kaiser","researchInterest":""},{"lastName":"Mysore","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9400&type=small&showNoImage","displayName":"Shreesh P. Mysore","firstName":"Shreesh","href":"http://med.stanford.edu/profiles/Shreesh_Mysore","researchInterest":"We are constantly faced with a complex sensory environment containing numerous stimuli. However, at each instant, only a small subset of this information filters through to working memory and captures our attention. A key component of this filter is competitive selection, i.e., the selection of the most salient stimulus. With electrophysiology, I study the mechanisms of bottom-up and top-down competitive stimulus selection in the barn owl optic tectum (avian homolog of the superior colliculus)."},{"lastName":"Kopito","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6227&type=small&showNoImage","displayName":"Ron Kopito","firstName":"Ron","href":"http://med.stanford.edu/profiles/Ron_Kopito","researchInterest":"Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells.  We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins."},{"lastName":"LI","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9800&type=small&showNoImage","displayName":"QING LI","firstName":"QING","href":"http://med.stanford.edu/profiles/QING_LI","researchInterest":"In embryonic/neonatal life, there is a wave of developmentally programmed islet cell death (apoptosis) in the pancreas in mice, rats, and humans.  Using gene chips, we have found that the gene expression of a number of genes activated by type 1 interferon (interferon alpha) increases sharply between postnatal weeks 3 and 4.  This is coincident with the time when large amounts of cellular breakdown products are released in the islets of Langerhans by a wave of developmentally programmed cell dea"},{"lastName":"Hallmayer","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Child Psychiatry"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Child Psychiatry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4056&type=small&showNoImage","displayName":"Joachim Hallmayer","firstName":"Joachim","href":"http://med.stanford.edu/profiles/Joachim_Hallmayer","researchInterest":"Principal Investigator\r\nInfrastructure to facilitate discovery of autism genes\r\nThe purpose of this project is to facilitate the discovery of the genes that contribute autism by maintaining an infrastructure which research groups studying the genetics of autism can work collaboratively. This will be \r\naccomplished through workshops, a Virtual Private Network, and access to a database that includes phenotype and genotype data from all participating groups.\r\n\r\nPrincipal Investigator\r\nA California"},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Yanofsky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","displayName":"Charles Yanofsky","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Yanofsky","researchInterest":""},{"lastName":"Cooke","clinicalFocus":[{"focus":"Cardiology (Heart)"},{"focus":"Cardiology (Heart), Preventive"},{"focus":"Cardiovascular Disease"},{"focus":"Vascular Medicine"}],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4115&type=small&showNoImage","displayName":"John Cooke, MD, PhD","firstName":"John","href":"http://med.stanford.edu/profiles/John_Cooke","researchInterest":"Our translational research program involves molecular, cellular, animal and human studies of endothelial biology. We are focused on the role of nitric oxide synthase (NOS) in atherosclerosis and angiogenesis.  A new focus of investigation has resulted from our discovery of a novel angiogenic pathway mediated by endothelial nicotinic cholinergic receptors (nAChR). We use a wide variety of tools and approaches to investigate the role of NOS and nAChR pathways in cardiovascular biology and disease."},{"lastName":"Weis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","displayName":"William Weis","firstName":"William","href":"http://med.stanford.edu/profiles/William_Weis","researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion."},{"lastName":"Ptacek","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8953&type=small&showNoImage","displayName":"Jennifer B. Ptacek","firstName":"Jennifer","href":"http://med.stanford.edu/profiles/Jennifer_Ptacek","researchInterest":""},{"lastName":"Frydman","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6222&type=small&showNoImage","displayName":"Judith Frydman","firstName":"Judith","href":"http://med.stanford.edu/profiles/Judith_Frydman","researchInterest":"The long term goal  of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether  reengineering chaperone networks can provide therapeutic strategies."},{"lastName":"Reichelt","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9514&type=small&showNoImage","displayName":"Mike Reichelt","firstName":"Mike","href":"http://med.stanford.edu/profiles/Mike_Reichelt","researchInterest":""},{"lastName":"McMahan","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurobiology"},{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4104&type=small&showNoImage","displayName":"Uel Jackson McMahan","firstName":"Uel","href":"http://med.stanford.edu/profiles/Uel_McMahan","researchInterest":"We are currently investigating mechanisms involved in synaptic transmission and synaptogenesis using electron microscope tomography in ways that provide in situ 3D structural information at macromolecular resolution."},{"lastName":"Grabrucker","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14853&type=small&showNoImage","displayName":"Andreas Grabrucker","firstName":"Andreas","href":"http://med.stanford.edu/profiles/Andreas_Grabrucker","researchInterest":""},{"lastName":"Yizhar","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","displayName":"Ofer Yizhar","firstName":"Ofer","href":"http://med.stanford.edu/profiles/Ofer_Yizhar","researchInterest":""},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Lewis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4176&type=small&showNoImage","displayName":"Richard Lewis","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Lewis","researchInterest":"We study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function.  Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development."}]}