{"result":[{"lastName":"McLaughlin","clinicalFocus":[{"focus":"Endocrinology / Diabetes"},{"focus":"Endocrinology and Metabolism"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Endocrinology, Gerontology, & Metabolism"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6107&type=small&showNoImage","displayName":"Tracey McLaughlin","firstName":"Tracey","href":"http://med.stanford.edu/profiles/Tracey_McLaughlin","researchInterest":"Dr. McLaughlin conducts a number of clinical research studies related to obesity, insulin resistance, diabetes, and cardiovascular disease. Current studies include: 1) the impact of macronutrient composition on weight loss and cardiocascular risk (diabetic and nondiabetic patients); 2) comparison of weight loss and cardiovascular risk reduction in diabetic patients treated with different classes of antihyperglycemic drugs; 3) the role of the adipocyte in modulating insulin resistance"},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Basina","clinicalFocus":[{"focus":"Endocrinology"},{"focus":"Type 1 Diabetes Mellitus"},{"focus":"Type 2 Diabetes Mellitus"},{"focus":"Thyroid Diseases"},{"focus":"Diabetes andMetabolism"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Endocrinology, Gerontology, & Metabolism"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8519&type=small&showNoImage","displayName":"Marina Basina","firstName":"Marina","href":"http://med.stanford.edu/profiles/Marina_Basina","researchInterest":"Type I and type II diabetes, insulin pump therapy, glucose sensor technology, insulin resistance, PCOS, thyroid disorders"},{"lastName":"Yue","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8441&type=small&showNoImage","displayName":"Patrick Yue","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Yue","researchInterest":"My primary research focus has been the mechanisms of insulin resistance and diabetes as they pertain to the heart.  I am particularly interested in the potential involvement of the recently discovered peptide hormone apelin.  Recent studies in my laboratory group have focused on apelin's role in promoting insulin sensitivity on the systemic, tissue-specific, and cellular level.  We are currently investigating apelin-mediated signaling events in insulin-sensitive and -resistant cardiac muscle."},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Reaven","clinicalFocus":[{"focus":"Endocrinology"},{"focus":"Endocrinology / Diabetes"}],"appointments":[{"appointment":"Professor Emeritus,Medicine - Cardiovascular Medicine"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor Emeritus,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5955&type=small&showNoImage","displayName":"Gerald Reaven, MD","firstName":"Gerald","href":"http://med.stanford.edu/profiles/Gerald_Reaven","researchInterest":""},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Rodgers","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19007&type=small&showNoImage","displayName":"Joseph T. Rodgers","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Rodgers","researchInterest":""},{"lastName":"Collins","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10605&type=small&showNoImage","displayName":"Sean Collins","firstName":"Sean","href":"http://med.stanford.edu/profiles/Sean_Collins","researchInterest":""},{"lastName":"Sherlock","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5864&type=small&showNoImage","displayName":"Gavin Sherlock","firstName":"Gavin","href":"http://med.stanford.edu/profiles/Gavin_Sherlock","researchInterest":"Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species"},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Teruel","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14171&type=small&showNoImage","displayName":"Mary Frances Nunez Teruel","firstName":"Mary","href":"http://med.stanford.edu/profiles/Mary_Teruel","researchInterest":"The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity."},{"lastName":"Singh","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29866&type=small&showNoImage","displayName":"Amar Singh","firstName":"Amar","href":"http://med.stanford.edu/profiles/Amar_Singh","researchInterest":""},{"lastName":"Zarafshar","clinicalFocus":[{"focus":"Internal Medicine"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - General Medical Disciplines"}],"primaryAppointment":"Clinical Instructor,Medicine - General Medical Disciplines","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36463&type=small&showNoImage","displayName":"Shirin Zarafshar","firstName":"Shirin","href":"http://med.stanford.edu/profiles/Shirin_Zarafshar","researchInterest":""},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Kraemer","clinicalFocus":[{"focus":"Endocrinology / Diabetes"},{"focus":"Lipid Metabolism Disorders"},{"focus":"Endocrinology and Metabolism"}],"appointments":[{"appointment":"Professor,Medicine - Endocrinology, Gerontology, & Metabolism"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4133&type=small&showNoImage","displayName":"Fredric Kraemer","firstName":"Fredric","href":"http://med.stanford.edu/profiles/Fredric_Kraemer","researchInterest":"Our research interests are in the general area of cellular lipid and lipoprotein metabolism. The work is aimed primarily at understanding the mechanisms regulating cholesterol and triglyceride accumulation in cells. We utilize a variety of techniques from cell biology, biochemistry, and molecular biology."},{"lastName":"Mulholland","clinicalFocus":[],"appointments":[{"appointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine"},{"appointment":"Research & Development Engr,Dean's Office - Center for Molecular and Genetic Medicine"}],"primaryAppointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=26450&type=small&showNoImage","displayName":"Jonathan Mulholland","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Mulholland","researchInterest":""},{"lastName":"Farquhar","clinicalFocus":[{"focus":"Cardiology (Heart), Preventive"},{"focus":"Cardiovascular Medicine"},{"focus":"Chronic Disease Prevention"},{"focus":"Global cancer prevention"}],"appointments":[{"appointment":"Professor Emeritus,Medicine - Stanford Prevention Research Center"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Stanford Prevention Research Center"}],"primaryAppointment":"Professor Emeritus,Medicine - Stanford Prevention Research Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5956&type=small&showNoImage","displayName":"John W. Farquhar, M.D.","firstName":"John","href":"http://med.stanford.edu/profiles/John_Farquhar","researchInterest":"Disease prevention, epidemiology of cardiovascular diseases, community-based education for disease prevention, international health."},{"lastName":"Vemuri","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Clinical Assistant Professor,Psychiatry & Behavioral Science - Behavioral Medicine"}],"primaryAppointment":"Clinical Assistant Professor,Psychiatry & Behavioral Science - Behavioral Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7649&type=small&showNoImage","displayName":"Mytilee Vemuri","firstName":"Mytilee","href":"http://med.stanford.edu/profiles/Mytilee_Vemuri","researchInterest":""},{"lastName":"Fraser","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15112&type=small&showNoImage","displayName":"Hunter Fraser","firstName":"Hunter","href":"http://med.stanford.edu/profiles/Hunter_Fraser","researchInterest":""},{"lastName":"Morrison","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14873&type=small&showNoImage","displayName":"Ashby Morrison","firstName":"Ashby","href":"http://med.stanford.edu/profiles/Ashby_Morrison","researchInterest":"Our research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity."},{"lastName":"Breslow","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19226&type=small&showNoImage","displayName":"David Breslow","firstName":"David","href":"http://med.stanford.edu/profiles/David_Breslow","researchInterest":""},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."}]}