{"result":[{"lastName":"Mellins","clinicalFocus":[{"focus":"Pediatric Rheumatology"},{"focus":"Rheumatology, Pediatric"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Human Gene Therapy"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Human Gene Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5952&type=small&showNoImage","displayName":"Elizabeth Mellins","firstName":"Elizabeth","href":"http://med.stanford.edu/profiles/Elizabeth_Mellins","researchInterest":"Molecular mechanisms and intracellular pathways of antigen processing and presentation; structure/function of HLA-DR,-DM, -DO; HLA allele association with disease; pathogen evasion of the class II pathway."},{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","displayName":"Chris Garcia","firstName":"Chris","href":"http://med.stanford.edu/profiles/Chris_Garcia","researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches."},{"lastName":"Ohlson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9289&type=small&showNoImage","displayName":"Maikke Ohlson","firstName":"Maikke","href":"http://med.stanford.edu/profiles/Maikke_Ohlson","researchInterest":""},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","displayName":"Oleg Jardetzky","firstName":"Oleg","href":"http://med.stanford.edu/profiles/Oleg_Jardetzky","researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure"},{"lastName":"Glauser","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8969&type=small&showNoImage","displayName":"Dominique Glauser","firstName":"Dominique","href":"http://med.stanford.edu/profiles/Dominique_Glauser","researchInterest":""},{"lastName":"Solomon","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8081&type=small&showNoImage","displayName":"Edward Solomon","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Solomon","researchInterest":""},{"lastName":"Weis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","displayName":"William Weis","firstName":"William","href":"http://med.stanford.edu/profiles/William_Weis","researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion."},{"lastName":"Vasquez","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Mechanical Engineering"}],"primaryAppointment":"Postdoctoral Research fellow, Mechanical Engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12553&type=small&showNoImage","displayName":"Valeria Vasquez","firstName":"Valeria","href":"http://med.stanford.edu/profiles/Valeria_Vasquez","researchInterest":""},{"lastName":"Kaiser","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10008&type=small&showNoImage","displayName":"Stephen Kaiser","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Kaiser","researchInterest":""},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Levitt","researchInterest":"Is it possible to understand the molecular structure and function of proteins and nucleic acids in enough detail to make accurate predictions about structure and function? We are mounting a two-pronged attack on this problem using both molecular dynamics simulation and molecular modeling."},{"lastName":"Lassila","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8633&type=small&showNoImage","displayName":"Jonathan Lassila","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Lassila","researchInterest":""},{"lastName":"Matin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4329&type=small&showNoImage","displayName":"AC Matin","firstName":"AC","href":"http://med.stanford.edu/profiles/AC_Matin","researchInterest":"1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity; 4. Bioremediation."},{"lastName":"Das","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biochemistry"}],"primaryAppointment":"Assistant Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10421&type=small&showNoImage","displayName":"Rhiju Das","firstName":"Rhiju","href":"http://med.stanford.edu/profiles/Rhiju_Das","researchInterest":"Rhiju Das strives to predict how sequence codes for structure in proteins, nucleic acids, and heteropolymers whose folds have yet to be explored. The Das group uses new computational and experimental tools to tackle the de novo modeling of protein and RNA folds, the high-throughput structure mapping of riboswitches and random RNAs, and the design of self-knotting and self-crystallizing nucleic acids."},{"lastName":"Lundin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8977&type=small&showNoImage","displayName":"Victor Lundin","firstName":"Carl","href":"http://med.stanford.edu/profiles/Carl_Lundin","researchInterest":"I am interested in the diverse ways that cells regulate their cytoskeletal systems, and how this affects processes such as intracellular transport and cell motility in normal and disease states. The development, communal behavior and long-term survival of neurons are particularly sensitive to cytoskeletal changes due to their unique morphology. I am currently investigating the pathological mechanisms of neurodegenerative and neurodevelopmental diseases at the cellular and molecular levels."},{"lastName":"Kasson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Chemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9965&type=small&showNoImage","displayName":"Peter Kasson","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Kasson","researchInterest":""},{"lastName":"Boucard","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9569&type=small&showNoImage","displayName":"Antony Boucard","firstName":"Antony","href":"http://med.stanford.edu/profiles/Antony_Boucard","researchInterest":""},{"lastName":"Kim","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9655&type=small&showNoImage","displayName":"Kwang-sun Kim","firstName":"Kwang-sun","href":"http://med.stanford.edu/profiles/Kwang-sun_Kim","researchInterest":""},{"lastName":"Boxer","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8050&type=small&showNoImage","displayName":"Steven Boxer","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Boxer","researchInterest":""},{"lastName":"Mani","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9136&type=small&showNoImage","displayName":"Maheswaran Mani","firstName":"Maheswaran","href":"http://med.stanford.edu/profiles/Maheswaran_Mani","researchInterest":""},{"lastName":"Frydman","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6222&type=small&showNoImage","displayName":"Judith Frydman","firstName":"Judith","href":"http://med.stanford.edu/profiles/Judith_Frydman","researchInterest":"The long term goal  of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether  reengineering chaperone networks can provide therapeutic strategies."},{"lastName":"Baldwin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6816&type=small&showNoImage","displayName":"Robert Baldwin","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Baldwin","researchInterest":"I closed my laboratory when I retired in 1998.  I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation,  and to write reviews."},{"lastName":"Harbury","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4433&type=small&showNoImage","displayName":"Pehr Harbury","firstName":"Pehr","href":"http://med.stanford.edu/profiles/Pehr_Harbury","researchInterest":"Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides."},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Minary","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10270&type=small&showNoImage","displayName":"Peter Minary","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Minary","researchInterest":""}]}