{"result":[{"lastName":"Barres","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","displayName":"Ben Barres","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Barres","researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system."},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"van Amerongen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9613&type=small&showNoImage","displayName":"Renee van Amerongen","firstName":"Renee","href":"http://med.stanford.edu/profiles/Renee_van Amerongen","researchInterest":"Alternative modes of Wnt-signal transduction"},{"lastName":"Emery","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9345&type=small&showNoImage","displayName":"Ben Emery","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Emery","researchInterest":""},{"lastName":"Palmer","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","displayName":"Theo Palmer","firstName":"Theo","href":"http://med.stanford.edu/profiles/Theo_Palmer","researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair."},{"lastName":"Talbot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4013&type=small&showNoImage","displayName":"William Talbot","firstName":"William","href":"http://med.stanford.edu/profiles/William_Talbot","researchInterest":"We use genetic and cellular approaches to investigate the molecular basis of glial development and myelination in the zebrafish. Other projects include the genetic dissection of cell fate specification in the early embryo and functional genomics in zebrafish."},{"lastName":"McConnell","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5928&type=small&showNoImage","displayName":"Susan McConnell","firstName":"Susan","href":"http://med.stanford.edu/profiles/Susan_McConnell","researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate."},{"lastName":"Axelrod","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4410&type=small&showNoImage","displayName":"Jeffrey Axelrod","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/Jeffrey_Axelrod","researchInterest":"Genetic and cell biological analyses of signals controlling cell polarity and cell proliferation and differentiation.  Frizzled signaling and cytoskeletal organization."},{"lastName":"Gurtner","clinicalFocus":[{"focus":"Plastic Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6890&type=small&showNoImage","displayName":"Geoffrey Gurtner","firstName":"Geoffrey","href":"http://med.stanford.edu/profiles/Geoffrey_Gurtner","researchInterest":"Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/Ching-Pin_Chang","researchInterest":"My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues.  We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues.  The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the devel"},{"lastName":"Webb","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9984&type=small&showNoImage","displayName":"Ashley Webb","firstName":"Ashley","href":"http://med.stanford.edu/profiles/Ashley_Webb","researchInterest":"Stem cell function requires both the establishment and maintenance of particular epigenetic states. Perturbation of the epigenetic status of stem cells may compromise both self-renewal and multipotency. Work from our lab has identified the Forkhead family transcription factor, FoxO3, as a regulator of adult neural stem cell (NSCs) quiescence, which prevents the depletion of this population of cells. Along with recent evidence that Forkhead family members act as \u0091pioneer factors\u0092 in the opening "},{"lastName":"Helms","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Surgery - Plastic/Recon Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6152&type=small&showNoImage","displayName":"Jill Helms","firstName":"Jill","href":"http://med.stanford.edu/profiles/Jill_Helms","researchInterest":"Dr. Helms' research interests center around craniofacial development and regenerative medicine."},{"lastName":"Stankunas","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9759&type=small&showNoImage","displayName":"Kryn Stankunas","firstName":"Kryn","href":"http://med.stanford.edu/profiles/Kryn_Stankunas","researchInterest":""},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/Calvin_Kuo","researchInterest":"Our laboratory explores a variety of projects including angiogenesis, intestinal stem cell biology, and hepatic insulin resistance. Studies in angiogenesis include characterization of endothelial microRNA and GPCR ko mice, and anti-angiogenic therapy of cancer.  Our work on intestinal stem cell biology utilizes primary intestinal culture and in vivo adenoviral/ko strategies to study stem cells and model colon cancer.  Investigations into mechanisms of hepatic insulin resistance are underway."},{"lastName":"Monk","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9455&type=small&showNoImage","displayName":"Kelly Monk","firstName":"Kelly","href":"http://med.stanford.edu/profiles/Kelly_Monk","researchInterest":""},{"lastName":"Blau","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4517&type=small&showNoImage","displayName":"Helen M. Blau","firstName":"Helen","href":"http://med.stanford.edu/profiles/Helen_Blau","researchInterest":"Molecular and cellular mechanisms that control muscle and neuronal growth; stem cell biology, differentiation, and tumorigenicity. Regulating stem cell fate in vitro and in vivo. Stem cell therapies. Hematopoietic and muscle stem cells. Characterizing and bioengineering stem cell niches. Nuclear reprogramming. Muscle development and disease. Drug delivery. Tracking cell behavior in vitro and in vivo. Understanding tissue degeneration and regeneration."},{"lastName":"Wernig","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Assistant Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10445&type=small&showNoImage","displayName":"Marius Wernig","firstName":"Marius","href":"http://med.stanford.edu/profiles/Marius_Wernig","researchInterest":"Epigenetic Reprogramming, Pluripotent Stem Cells, Neural Differentiation: implications in development and regenerative medicine"},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Brugmann","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9172&type=small&showNoImage","displayName":"Samantha Brugmann","firstName":"Samantha","href":"http://med.stanford.edu/profiles/Samantha_Brugmann","researchInterest":"Craniofacial development and  patterning"},{"lastName":"Heller","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Associate Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7084&type=small&showNoImage","displayName":"Stefan Heller","firstName":"Stefan","href":"http://med.stanford.edu/profiles/Stefan_Heller","researchInterest":"Most types of congenital and acquired hearing loss arise from damage to, or loss of hair cells, the sensory cells of the inner ear.  Our recent work has focused on generating inner ear cell types from stem cells and we are interested in signaling pathways that control hair cell and auditory neuron (re-)generation in vitro and in vivo.  In a second line of research, we are working on the identification and the molceular characterization of proteins that are important for hair cell function."},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Stockdale","clinicalFocus":[{"focus":"Breast Cancer - Medical Oncology"},{"focus":"Oncology"},{"focus":"Newly Diagnosed Breast Cancer"},{"focus":"Metastatic Breast Cancer"},{"focus":"Inflammatory Breast Cancer"},{"focus":"Locally Advanced Breast Cancer"},{"focus":"Chemotherapy, Adjuvant"},{"focus":"Ductal Carcinoma In Situ"},{"focus":"Phyllodes Tumor"}],"appointments":[{"appointment":"Emeritus (Active) Professor,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus (Active) Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4528&type=small&showNoImage","displayName":"Frank E. Stockdale","firstName":"Frank","href":"http://med.stanford.edu/profiles/Frank_Stockdale","researchInterest":"Laboratory and clinical research in breast cancer ; Normal and abornal differentiation and growth"},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Rando","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4063&type=small&showNoImage","displayName":"Thomas Rando","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Rando","researchInterest":"Our laboratory studies the basic molecular mechanisms of muscle stem cell activation, the effects of aging on skeletal muscle, and gene therapy for hereditary muscle diseases."}]}