{"result":[{"lastName":"Bernstein","clinicalFocus":[{"focus":"Autism"},{"focus":"Developmental Disorders"},{"focus":"Craniofacial Abnormalities"},{"focus":"Craniosynostosis"},{"focus":"Cleft Lip"},{"focus":"Cleft Palate"},{"focus":"General Pediatrics"}],"appointments":[{"appointment":"Clinical Assistant Professor,Pediatrics - Genetics"}],"primaryAppointment":"Clinical Assistant Professor,Pediatrics - Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8523&type=small&showNoImage","displayName":"Jon Bernstein","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Bernstein","researchInterest":"I am interested in the genetics of autism spectrum and other developmental disorders.   In collaboration with the laboratories of Dr. Ricardo Dolmetsch and Joachim Hallmayer I am working to develop induced pluripotent stem cell (iPSC) models of genetic disorders associated with autism and developmental disability."},{"lastName":"Cohen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4481&type=small&showNoImage","displayName":"Stanley N. Cohen, MD","firstName":"Stanley","href":"http://med.stanford.edu/profiles/Stanley_Cohen","researchInterest":"We study the functional and structural signals that govern mRNA decay and gene expression in bacteria, as well as mechanisms affecting aging and the ability of mammalian cells to support the propagation of viruses.  A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of gene expression on a genome-wide basis."},{"lastName":"Matin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4329&type=small&showNoImage","displayName":"AC Matin","firstName":"AC","href":"http://med.stanford.edu/profiles/AC_Matin","researchInterest":"1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity; 4. Bioremediation."},{"lastName":"Puglisi","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4431&type=small&showNoImage","displayName":"Joseph (Jody) Puglisi","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Puglisi","researchInterest":"The Puglisi group investigates the role of RNA in cellular processes and disease.  We investigate dynamics using single-molecule approaches.  Our goal is a unified picture of structure, dynamics and function.  We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections.  A long-term goal is to target processes involving RNA with novel therapeutic strategies."},{"lastName":"Yanofsky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","displayName":"Charles Yanofsky","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Yanofsky","researchInterest":""},{"lastName":"Hershberg","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10299&type=small&showNoImage","displayName":"Ruth Hershberg","firstName":"Ruth","href":"http://med.stanford.edu/profiles/Ruth_Hershberg","researchInterest":"The aim of my research is to investigate the mechanisms, frequency, and consequences of the evolutionary shifts experienced by bacteria. Some more specific areas of research include:\r\n\r\n(1)  Quantifying shifts in the strength of purifying selection and understanding the consequences of such shifts\r\n \r\n(2)  Determining whether shifts in nucleotide content are driven by shifts in mutation or shifts in selection\r\n\r\n(3)  Establishing the mechanisms of shifts in codon usage bias"},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Covert","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7986&type=small&showNoImage","displayName":"Markus Covert","firstName":"Markus","href":"http://med.stanford.edu/profiles/Markus_Covert","researchInterest":"Our focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors."},{"lastName":"Lassila","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8633&type=small&showNoImage","displayName":"Jonathan Lassila","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Lassila","researchInterest":""},{"lastName":"Phillips","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9437&type=small&showNoImage","displayName":"Neil Phillips","firstName":"Neil","href":"http://med.stanford.edu/profiles/Neil_Phillips","researchInterest":""},{"lastName":"Altman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Bioengineering"},{"appointment":"Professor,Medicine - BMIR"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4706&type=small&showNoImage","displayName":"Russ B. Altman","firstName":"Russ","href":"http://med.stanford.edu/profiles/Russ_Altman","researchInterest":"I refer you to my web page for detailed list of interests, projects and publications.  In addition to pressing the link here, you can search \"Russ Altman\" on http://www.google.com/"},{"lastName":"Kalisky","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10137&type=small&showNoImage","displayName":"Tomer Kalisky","firstName":"Tomer","href":"http://med.stanford.edu/profiles/Tomer_Kalisky","researchInterest":"Single cell gene expression, cancer stem cells, biological networks, systems biology"},{"lastName":"Harbury","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4433&type=small&showNoImage","displayName":"Pehr Harbury","firstName":"Pehr","href":"http://med.stanford.edu/profiles/Pehr_Harbury","researchInterest":"Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Puglisi","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Structural Biology"}],"primaryAppointment":"Assistant Professor (Research),Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10456&type=small&showNoImage","displayName":"Elisabetta Viani Puglisi","firstName":"Elisabetta","href":"http://med.stanford.edu/profiles/Elisabetta_Puglisi","researchInterest":"Viral infections and subsequent host response depend on multiple RNA-protein interaction. My research focuses on the structural and functional characterization of RNA-protein complexes involved in viral infection. Current research aims to understand how the Human Immunodeficiency Virus (HIV) initiates its replication upon host infection. We use NMR spectroscopy and x-ray crystallography to study the structure of the initiation complex, formed by a host tRNA and HIV genomic RNA, coupled with bio"},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7014&type=small&showNoImage","displayName":"Kendric C. Smith","firstName":"Kendric","href":"http://med.stanford.edu/profiles/Kendric_Smith","researchInterest":"The photochemistry and radiation chemistry of DNA, the genetic control and biochemical bases of the multiple pathways of DNA repair, and the roles of DNA repair processes in radiation and spontaneous mutagenesis. Over 190 papers have been published on these and related topics."},{"lastName":"Das","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biochemistry"}],"primaryAppointment":"Assistant Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10421&type=small&showNoImage","displayName":"Rhiju Das","firstName":"Rhiju","href":"http://med.stanford.edu/profiles/Rhiju_Das","researchInterest":"Rhiju Das strives to predict how sequence codes for structure in proteins, nucleic acids, and heteropolymers whose folds have yet to be explored. The Das group uses new computational and experimental tools to tackle the de novo modeling of protein and RNA folds, the high-throughput structure mapping of riboswitches and random RNAs, and the design of self-knotting and self-crystallizing nucleic acids."},{"lastName":"Vasquez","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Mechanical Engineering"}],"primaryAppointment":"Postdoctoral Research fellow, Mechanical Engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12553&type=small&showNoImage","displayName":"Valeria Vasquez","firstName":"Valeria","href":"http://med.stanford.edu/profiles/Valeria_Vasquez","researchInterest":""},{"lastName":"Campbell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6212&type=small&showNoImage","displayName":"Allan Campbell","firstName":"Allan","href":"http://med.stanford.edu/profiles/Allan_Campbell","researchInterest":""},{"lastName":"Block","clinicalFocus":[],"appointments":[{"appointment":"Professor,Applied Physics"},{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Senior Fellow (By courtesy),Spogli Inst for Intrntl Studies"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Applied Physics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6209&type=small&showNoImage","displayName":"Steven M. Block","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Block","researchInterest":""},{"lastName":"Lesley","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8857&type=small&showNoImage","displayName":"Joseph Lesley","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Lesley","researchInterest":""},{"lastName":"Shapiro","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Senior Fellow (By courtesy),Spogli Inst for Intrntl Studies"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4316&type=small&showNoImage","displayName":"Lucy Shapiro","firstName":"Lucille","href":"http://med.stanford.edu/profiles/Lucille_Shapiro","researchInterest":"A basic question in developmental biology involves the mechanisms used to generate the three-dimensional organization of a cell from a one-dimensional genetic code. Our goal is to define these mechanisms using both molecular genetics and biochemistry."},{"lastName":"Rao","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Radiology - Diagnostic Radiology"},{"appointment":"Assistant Professor (By courtesy),Chemistry"}],"primaryAppointment":"Assistant Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6019&type=small&showNoImage","displayName":"Jianghong Rao","firstName":"Jianghong","href":"http://med.stanford.edu/profiles/Jianghong_Rao","researchInterest":""},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"McAdams","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4403&type=small&showNoImage","displayName":"Harley McAdams","firstName":"Harley","href":"http://med.stanford.edu/profiles/Harley_McAdams","researchInterest":"Experimental and theoretical analysis and modeling of genetic regulatory circuits, particularly bacterial regulation and with emphasis on global regulation of Caulobacter crescentus. Bioinformatic analysis of bacterial genomes, of microarray expression patterns, and cross-species genomic analysis. Techniques: gene expression microarrays, fluorescent microscopy, electron microscopy."}]}