{"result":[{"lastName":"Zaleta Rivera","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10991&type=small&showNoImage","displayName":"Kathia Zaleta, PhD","firstName":"Kathia","href":"http://med.stanford.edu/profiles/Kathia_Zaleta Rivera","researchInterest":""},{"lastName":"Gray","clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Inflammatory Bowel Disease"},{"focus":"Intestinal Malabsorption"},{"focus":"Small Intestinal Diseases"}],"appointments":[{"appointment":"Professor Emeritus,Medicine - Gastroenterology & Hepatology"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Gastroenterology & Hepatology"}],"primaryAppointment":"Professor Emeritus,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6183&type=small&showNoImage","displayName":"Gary M Gray","firstName":"Gary","href":"http://med.stanford.edu/profiles/Gary_Gray","researchInterest":""},{"lastName":"Dafik","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10495&type=small&showNoImage","displayName":"Laila Dafik","firstName":"Laila","href":"http://med.stanford.edu/profiles/Laila_Dafik","researchInterest":""},{"lastName":"Yeh","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Clinical Microbiology"}],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Assistant Professor,Microbiology & Immunology"},{"appointment":"Assistant Professor,Biochemistry"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23613&type=small&showNoImage","displayName":"Ellen Yeh","firstName":"Ellen","href":"http://med.stanford.edu/profiles/Ellen_Yeh","researchInterest":"The chemistry and biology of the unusual plastid organelle, the apicoplast, in malaria parasites"},{"lastName":"Wender","clinicalFocus":[],"appointments":[{"appointment":"Professor,Natural Sciences Cluster - Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Natural Sciences Cluster - Chemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6111&type=small&showNoImage","displayName":"Paul Wender","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Wender","researchInterest":""},{"lastName":"Harvey","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34542&type=small&showNoImage","displayName":"Colin Harvey","firstName":"Colin","href":"http://med.stanford.edu/profiles/Colin_Harvey","researchInterest":""},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Computer Science"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Levitt","researchInterest":"having pioneered, we (a) predict folding of a polypeptide and RNA chains into a unique native-structure, we (b) model protein structure using the well-established paradigms that similar protein sequences imply similar three-dimensional structures, and (c) we are focusing on mesoscale modeling of large macromolecular complexes such as RNA polymerase and the mammalian chaperonin."},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=39176&type=small&showNoImage","displayName":"Yanran Li","firstName":"Yanran","href":"http://med.stanford.edu/profiles/Yanran_Li","researchInterest":""},{"lastName":"Bogyo","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3957&type=small&showNoImage","displayName":"Matthew Bogyo","firstName":"Matthew","href":"http://med.stanford.edu/profiles/Matthew_Bogyo","researchInterest":"Our lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include: \r\n\r\n1) Design and synthesis of novel chemical probes for each of the primary protease families.\r\n\r\n2) Understanding the role of proteolysis in the life cycle of the human parasites, Plasmodium falciparum and Toxoplasma gondii.\r\n\r\n3) Defining the specific functional roles of proteases during the process of tumorogenesis.\r\n\r\n4) In vivo imaging of protease activity"},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Cochran","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor (By courtesy),Chemical Engineering"}],"primaryAppointment":"Associate Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6393&type=small&showNoImage","displayName":"Jennifer R. Cochran","firstName":"Jennifer","href":"http://med.stanford.edu/profiles/Jennifer_Cochran","researchInterest":"Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging"},{"lastName":"Feng","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35054&type=small&showNoImage","displayName":"Liang Feng","firstName":"Liang","href":"http://med.stanford.edu/profiles/Liang_Feng","researchInterest":"We are interested in the structure, dynamics and function of eukaryotic transport proteins mediating ions and major nutrients crossing the membrane, the kinetics and regulation of transport processes, the catalytic mechanism of membrane embedded enzymes and the development of small molecule modulators based on the structure and function of membrane proteins."},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","displayName":"Oleg Jardetzky","firstName":"Oleg","href":"http://med.stanford.edu/profiles/Oleg_Jardetzky","researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure"},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Mallick","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18938&type=small&showNoImage","displayName":"Parag Mallick","firstName":"Parag","href":"http://med.stanford.edu/profiles/Parag_Mallick","researchInterest":"Our research centers on developing and applying  proteomics and systems biology approaches to quantitatively describe organisms' physiologic states towards the goal of enabling personalized, predictive medicine.  As part of this effort we are trying to characterize the diverse states of cells (using proteomic and transcriptomic methods) and how signals describing those states are propagated from molecular and cellular length scales to tumor and organismic length scales."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Baldwin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6816&type=small&showNoImage","displayName":"Robert Baldwin","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Baldwin","researchInterest":"I closed my laboratory when I retired in 1998.  I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation,  and to write reviews."},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Engr Res Assoc,Genetics"}],"primaryAppointment":"Engr Res Assoc,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9027&type=small&showNoImage","displayName":"Tianyun Liu","firstName":"Tianyun","href":"http://med.stanford.edu/profiles/Tianyun_Liu","researchInterest":""},{"lastName":"MacMillan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9498&type=small&showNoImage","displayName":"Henriette MacMillan","firstName":"Henriette","href":"http://med.stanford.edu/profiles/Henriette_MacMillan","researchInterest":""},{"lastName":"Yanofsky","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","displayName":"Charles Yanofsky","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Yanofsky","researchInterest":""},{"lastName":"Sathiyamoorthy","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21151&type=small&showNoImage","displayName":"Karthik Sathiyamoorthy","firstName":"Karthik","href":"http://med.stanford.edu/profiles/Karthik_Sathiyamoorthy","researchInterest":""},{"lastName":"Elmlund","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23183&type=small&showNoImage","displayName":"Dominika Elmlund","firstName":"Dominika","href":"http://med.stanford.edu/profiles/Dominika_Elmlund","researchInterest":"I am interested in the structural biology of TFIID-dependent transcription. My investigations are focused toward determining the roles of TBP-lacking and TBP-containing TFIID states in the dynamic transcription initiation process. I am also involved in development of new computational methods for 3D structure determination from electron microscopic projection images of single-particles. The collection of algorithms developed so far constitutes a new open source software package SIMPLE (Single-p"}]}