{"result":[{"lastName":"Talbot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4013&type=small&showNoImage","displayName":"William Talbot","firstName":"William","href":"http://med.stanford.edu/profiles/William_Talbot","researchInterest":"We use genetic and cellular approaches to investigate the molecular basis of glial development and myelination in the zebrafish. Other projects include the genetic dissection of cell fate specification in the early embryo and functional genomics in zebrafish."},{"lastName":"Webb","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9984&type=small&showNoImage","displayName":"Ashley Webb","firstName":"Ashley","href":"http://med.stanford.edu/profiles/Ashley_Webb","researchInterest":"Stem cell function requires both the establishment and maintenance of particular epigenetic states. Perturbation of the epigenetic status of stem cells may compromise both self-renewal and multipotency. Work from our lab has identified the Forkhead family transcription factor, FoxO3, as a regulator of adult neural stem cell (NSCs) quiescence, which prevents the depletion of this population of cells. Along with recent evidence that Forkhead family members act as \u0091pioneer factors\u0092 in the opening "},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Assistant Professor (By courtesy),Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","displayName":"James K. Chen","firstName":"James","href":"http://med.stanford.edu/profiles/James_Chen","researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development."},{"lastName":"Shooter","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Neurobiology"}],"primaryAppointment":"Emeritus (Active) Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3996&type=small&showNoImage","displayName":"Eric Shooter","firstName":"Eric","href":"http://med.stanford.edu/profiles/Eric_Shooter","researchInterest":"The biochemistry and molecular genetics of growth and differentiation of nerve cells. The structure, biosynthesis and mechanism of action of nerve growth factor and other neurotrophins. Gene regulation in target organs and glial cells during nerve regeneration. The role of apolipoproteins and of the myelin protein PMP-22 during nerve degeneration and regeneration and in peripheral neuropathies."},{"lastName":"Agalliu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9742&type=small&showNoImage","displayName":"Dritan Agalliu PhD","firstName":"Dritan","href":"http://med.stanford.edu/profiles/Dritan_Agalliu","researchInterest":"I am interested in understanding the signaling pathways that regulate the development of specialized tight junctions in brain endothelial cells responsible for forming the blood-brain barrier. The identification of these signals is important for elucidating the mechanisms that regulate the entry of distinct compounds or drugs into the Central Nervous System (CNS) and the etiology of pathological CNS conditions associated with blood-brain barrier breakdown."},{"lastName":"Barres","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","displayName":"Ben Barres","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Barres","researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system."},{"lastName":"Emery","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9345&type=small&showNoImage","displayName":"Ben Emery","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Emery","researchInterest":""},{"lastName":"Rothenberg","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10397&type=small&showNoImage","displayName":"Michael Rothenberg","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Rothenberg","researchInterest":""},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7015&type=small&showNoImage","displayName":"Marion Smith","firstName":"Marion","href":"http://med.stanford.edu/profiles/Marion_Smith","researchInterest":""},{"lastName":"Axelrod","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4410&type=small&showNoImage","displayName":"Jeffrey Axelrod","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/Jeffrey_Axelrod","researchInterest":"Genetic and cell biological analyses of signals controlling cell polarity and cell proliferation and differentiation.  Frizzled signaling and cytoskeletal organization."},{"lastName":"Charo","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9189&type=small&showNoImage","displayName":"David Charo","firstName":"David","href":"http://med.stanford.edu/profiles/David_Charo","researchInterest":""},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","displayName":"Matthew Scott","firstName":"Matthew","href":"http://med.stanford.edu/profiles/Matthew_Scott","researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/Ching-Pin_Chang","researchInterest":"My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues.  We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues.  The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the devel"},{"lastName":"Steinman","clinicalFocus":[{"focus":"Neurology"},{"focus":"Neurology, Pediatric"},{"focus":"Multiple Sclerosis, Myasthenia Gravis, Immune Disorders"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor,Pediatrics"},{"appointment":"Professor (By courtesy),Genetics"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3784&type=small&showNoImage","displayName":"Lawrence Steinman","firstName":"Lawrence","href":"http://med.stanford.edu/profiles/Lawrence_Steinman","researchInterest":"Our laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis.  We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab.  We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids.  We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis."},{"lastName":"Hsu","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Obstetrics & Gynecology"}],"primaryAppointment":"Assistant Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4078&type=small&showNoImage","displayName":"Sheau Yu Teddy Hsu","firstName":"Sheau-Yu","href":"http://med.stanford.edu/profiles/Sheau-Yu_Hsu","researchInterest":""},{"lastName":"Hentz","clinicalFocus":[{"focus":"Plastic and Reconstructive Surgery"},{"focus":"Hand and Upper Extremity Surgery"},{"focus":"Hand Surgery"},{"focus":"Hand and Upper Extremity Surgery, Pediatric"},{"focus":"Brachial plexus"},{"focus":"Obstetrical brachial plexus palsy"},{"focus":"Malignant Peripheral Nerve Sheath Tumors"},{"focus":"Peripheral nerve injuries"},{"focus":"Dupuytren's Contracture"}],"appointments":[{"appointment":"Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Professor (By courtesy),Orthopaedic Surgery"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Surgery - Plastic/Recon Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3794&type=small&showNoImage","displayName":"Vincent Hentz","firstName":"Vincent","href":"http://med.stanford.edu/profiles/Vincent_Hentz","researchInterest":"1. Nerve regeneration and repair, evaluation of repair methods, modalities to enhance peripheral nerve regeneration, development of improved methods to analyze nerve regeneration.\r\n\r\n2. Implementation of functional neuromuscular stimulation to paralytic deformities.\r\n\r\n3. Computer modeling of upper limb function."},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"Schvarzstein","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9884&type=small&showNoImage","displayName":"Mara Schvarzstein","firstName":"Mara","href":"http://med.stanford.edu/profiles/Mara_Schvarzstein","researchInterest":""},{"lastName":"Kojima","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9671&type=small&showNoImage","displayName":"Yoko Kojima","firstName":"Yoko","href":"http://med.stanford.edu/profiles/Yoko_Kojima","researchInterest":""},{"lastName":"Nachury","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8391&type=small&showNoImage","displayName":"Maxence Nachury","firstName":"Maxence","href":"http://med.stanford.edu/profiles/Maxence_Nachury","researchInterest":"We study the primary cilium, a once-obscure cellular organelle recently \"re-discovered\" for its role in a number of signaling pathways. Defects in cilium biogenesis lead to a variety of hereditary disorders characterized by retinal degeneration, kidney cysts and obesity. Our goal is  to characterize these disorders at the molecular and cellular levels to gain insight into the basic mechanisms of primary cilium biogenesis and to discover novel ciliary signaling pathways."},{"lastName":"Luo","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor (By courtesy),Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6229&type=small&showNoImage","displayName":"Liqun Luo","firstName":"Liqun","href":"http://med.stanford.edu/profiles/Liqun_Luo","researchInterest":"We are studying how neural circuits are assembled during development, and how they contribute to sensory perception.  We are addressing these questions at different levels from molecular, cellular, circuit to animal behavior.  We are primarily using Drosophila as a model organism for our studies.  Most recently, we are also developing novel genetic tools in the mouse to extend our studies to the mammalian brain."},{"lastName":"Hsueh","clinicalFocus":[],"appointments":[{"appointment":"Professor,Obstetrics & Gynecology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4297&type=small&showNoImage","displayName":"Aaron Hsueh","firstName":"Aaron","href":"http://med.stanford.edu/profiles/Aaron_Hsueh","researchInterest":"Hormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors,  follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes."},{"lastName":"Tran","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9649&type=small&showNoImage","displayName":"David Tran","firstName":"David","href":"http://med.stanford.edu/profiles/David_Tran","researchInterest":""},{"lastName":"Hippenmeyer","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8871&type=small&showNoImage","displayName":"Simon Hippenmeyer","firstName":"Simon","href":"http://med.stanford.edu/profiles/Simon_Hippenmeyer","researchInterest":""},{"lastName":"Kroeger","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10811&type=small&showNoImage","displayName":"Daniel Kroeger","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Kroeger","researchInterest":""}]}