{"result":[{"lastName":"Bryant","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Structural Biology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8004&type=small&showNoImage","displayName":"Zev Bryant","firstName":"Zev","href":"http://med.stanford.edu/profiles/Zev_Bryant","researchInterest":"Molecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work."},{"lastName":"Hargreaves","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14395&type=small&showNoImage","displayName":"Diana Hargreaves","firstName":"Diana","href":"http://med.stanford.edu/profiles/Diana_Hargreaves","researchInterest":""},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Jacobson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34821&type=small&showNoImage","displayName":"Catherine Jacobson","firstName":"Catherine","href":"http://med.stanford.edu/profiles/Catherine_Jacobson","researchInterest":""},{"lastName":"Nag","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23884&type=small&showNoImage","displayName":"Suman Nag","firstName":"Suman","href":"http://med.stanford.edu/profiles/Suman_Nag","researchInterest":"Mutations in the beta-cardiac myosin (a molecular motor) cause disastrous effects by manifestation of hypertrophic and dilated cardiomyopathy, a leading cause of cardiac death. We hypothesize that the such mutations cause fundamental mechanistic changes in the motor which in turn affect the efficiency of the motor in several ways. My current research involves single molecule enzyme kinetics and force measurements to link intrinsic changes in motor function to the various clinical outcomes."},{"lastName":"Zhang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20469&type=small&showNoImage","displayName":"Zhenjie Zhang","firstName":"Zhenjie","href":"http://med.stanford.edu/profiles/Zhenjie_Zhang","researchInterest":""},{"lastName":"Spudich","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4609&type=small&showNoImage","displayName":"James Spudich","firstName":"James","href":"http://med.stanford.edu/profiles/James_Spudich","researchInterest":"The general research interest of this laboratory is the molecular basis of cell motility. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement and changes in cell shape."},{"lastName":"Ricci","clinicalFocus":[],"appointments":[{"appointment":"Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7527&type=small&showNoImage","displayName":"Anthony Ricci","firstName":"Anthony","href":"http://med.stanford.edu/profiles/Anthony_Ricci","researchInterest":"The auditory sensory cell, the hair cell, detects mechanical stimulation at the atomic level and conveys information regarding frequency and intensity to the brain with high fidelity. Our interests are in identifying specializations associated with mechanotransduction and synaptic transmission leading to the amazing sensitivities of the auditory system. We are also interested in the developmental process, particularly in how development gives insight into repair and regenerative mechanisms."},{"lastName":"Kim","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37002&type=small&showNoImage","displayName":"Juyoung Kim","firstName":"JUYOUNG","href":"http://med.stanford.edu/profiles/JUYOUNG_Kim","researchInterest":""},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Janda","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10499&type=small&showNoImage","displayName":"Claudia Janda","firstName":"Claudia","href":"http://med.stanford.edu/profiles/Claudia_Janda","researchInterest":""},{"lastName":"Mulholland","clinicalFocus":[],"appointments":[{"appointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine"},{"appointment":"Research & Development Engr,Dean's Office - Center for Molecular and Genetic Medicine"}],"primaryAppointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=26450&type=small&showNoImage","displayName":"Jonathan Mulholland","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Mulholland","researchInterest":""},{"lastName":"Doniach","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8062&type=small&showNoImage","displayName":"Sebastian Doniach","firstName":"Sebastian","href":"http://med.stanford.edu/profiles/Sebastian_Doniach","researchInterest":""},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8138&type=small&showNoImage","displayName":"Ted Jardetzky","firstName":"Theodore","href":"http://med.stanford.edu/profiles/Theodore_Jardetzky","researchInterest":"The Jardetzky laboratory is studying the structures and mechanisms of macromolecular complexes important in viral pathogenesis, allergic hypersensitivities and the regulation of cellular growth and differentiation, with an interest in uncovering novel conceptual approaches to intervening in disease processes.  Ongoing research projects include studies of paramyxovirus and herpesvirus entry mechanisms, IgE-receptor structure and function and TGF-beta ligand signaling pathways."},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://med.stanford.edu/profiles/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Tsetsenis","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10368&type=small&showNoImage","displayName":"Theodoros Tsetsenis","firstName":"Theodoros","href":"http://med.stanford.edu/profiles/Theodoros_Tsetsenis","researchInterest":""},{"lastName":"McMahan","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4104&type=small&showNoImage","displayName":"Uel Jackson McMahan","firstName":"Uel","href":"http://med.stanford.edu/profiles/Uel_McMahan","researchInterest":"We are currently investigating mechanisms involved in synaptic transmission and synaptogenesis using electron microscope tomography in ways that provide in situ 3D structural information at macromolecular resolution."},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","researchInterest":"Chromatin regulation and its roles in human cancer and the development of the nervous system.  Engineering new methods for studying and controlling chromatin in living cells."},{"lastName":"Sathiyamoorthy","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21151&type=small&showNoImage","displayName":"Karthik Sathiyamoorthy","firstName":"Karthik","href":"http://med.stanford.edu/profiles/Karthik_Sathiyamoorthy","researchInterest":""}]}