{"result":[{"lastName":"Andreasson","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences"}],"primaryAppointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7903&type=small&showNoImage","displayName":"Katrin Andreasson","firstName":"Katrin","href":"http://med.stanford.edu/profiles/Katrin_Andreasson","researchInterest":"Our research focuses on understanding disease mechanisms of stroke injury and neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS) as they relate to the COX-2-prostaglandin pathways.  We are identifying prostaglandin receptor pathways that are involved in these disease models, and our objective is to identify which receptors will be translationally relevant in human neurological disease."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells."},{"lastName":"Denko","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","displayName":"Nicholas Denko","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_Denko","researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes."},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonology (Lung) and Critical Care "}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Chawla","clinicalFocus":[{"focus":"Endocrinology / Diabetes"},{"focus":"Endocrinology and Metabolism"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Endocrinology/Gerontology/Metab"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Endocrinology/Gerontology/Metab","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3922&type=small&showNoImage","displayName":"Ajay Chawla","firstName":"Ajay","href":"http://med.stanford.edu/profiles/Ajay_Chawla","researchInterest":"We investigate the mechanisms by which nuclear receptors (such as PPARs) and coactivator proteins control programs of metabolism and inflammation in tissues.  Our work is highly pertinent to various disease states, such as type 2 diabetes mellitus, coronary artery disease, autoimmunity and aging."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Peehl","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Urology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4633&type=small&showNoImage","displayName":"Donna Peehl","firstName":"Donna","href":"http://med.stanford.edu/profiles/Donna_Peehl","researchInterest":"My research focuses on the molecular and cellular biology of the human prostate. Developing realistic experimental models is a major goal, and primary cultures of prostatic epithelial and stromal cells are my main model system. Our discoveries are relevant to prevention, detection, diagnosis and treatment of benign and malignant prostatic diseases."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Sun","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","displayName":"Zijie Sun","firstName":"Zijie","href":"http://med.stanford.edu/profiles/Zijie_Sun","researchInterest":"My laboratory focuses on understanding the transcriptional processes that govern the transformation of normal mammalian cells to neoplastic state."},{"lastName":"Brooks","clinicalFocus":[{"focus":"Male Cancers - Prostate "},{"focus":"Prostate Cancer"},{"focus":"Nerve-sparing radical prostatectomy"},{"focus":"Prostate Cancer - Urologic Oncology"},{"focus":"Urologic Cancers"},{"focus":"Urologic Cancers - Urologic Oncology"},{"focus":"Urology"}],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6178&type=small&showNoImage","displayName":"James D. Brooks","firstName":"James","href":"http://med.stanford.edu/profiles/James_Brooks","researchInterest":"We have used comprehensive gene expression profiling for 2 translational research objectives: 1) to understand the mechanisms of action of candidate prostate cancer preventive agents and develop biomarkers that we can use to evaluate response; and 2) to identify diagnostic and prognostic markers for prostate, kidney, testicular and bladder cancers."},{"lastName":"Chan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9968&type=small&showNoImage","displayName":"Denise Chan","firstName":"Denise","href":"http://med.stanford.edu/profiles/Denise_Chan","researchInterest":""},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Dalerba","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9693&type=small&showNoImage","displayName":"Piero Dalerba","firstName":"Piero","href":"http://med.stanford.edu/profiles/Piero_Dalerba","researchInterest":"Cancer Stem Cells, Colon Cancer"},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/Calvin_Kuo","researchInterest":"Our laboratory explores a variety of projects including angiogenesis, intestinal stem cell biology, and hepatic insulin resistance. Studies in angiogenesis include characterization of endothelial microRNA and GPCR ko mice, and anti-angiogenic therapy of cancer.  Our work on intestinal stem cell biology utilizes primary intestinal culture and in vivo adenoviral/ko strategies to study stem cells and model colon cancer.  Investigations into mechanisms of hepatic insulin resistance are underway."},{"lastName":"Hsueh","clinicalFocus":[],"appointments":[{"appointment":"Professor,Obstetrics & Gynecology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4297&type=small&showNoImage","displayName":"Aaron Hsueh","firstName":"Aaron","href":"http://med.stanford.edu/profiles/Aaron_Hsueh","researchInterest":"Hormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors,  follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes."},{"lastName":"Ameri","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8979&type=small&showNoImage","displayName":"Kurosh Ameri","firstName":"Kurosh","href":"http://med.stanford.edu/profiles/Kurosh_Ameri","researchInterest":"My research interests include the influence of tumor microenvironment on generation of circulating tumor cells (CTCs), which circulate the body and metastasize to distant organs. Specific interests: 1. The role of tumor hypoxia and tumor anoxia in generation of CTCs; 2. The role of anoxia factors in determing resistance to anti-angiogensis therapy; 3. Exploiting anoxia pathways in cancer imaging and CTC imaging; 4. Exploiting anoxia induced nutritional pathways in cancer therapy and imaging."},{"lastName":"Noonan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10537&type=small&showNoImage","displayName":"Emily Noonan Ph.D.","firstName":"Emily","href":"http://med.stanford.edu/profiles/Emily_Noonan","researchInterest":"chemoprevetion, HDAC inhibitors, miRNAs, tumor suppressor genes"},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Contag","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pediatrics - Neonatology"},{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Associate Professor (By courtesy),Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pediatrics - Neonatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4036&type=small&showNoImage","displayName":"Christopher H. Contag","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Contag","researchInterest":"We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in \"a vacuum\" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult."},{"lastName":"Pollack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","displayName":"Jonathan Pollack","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Pollack","researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies."},{"lastName":"Razorenova","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9869&type=small&showNoImage","displayName":"Olga Razorenova","firstName":"Olga","href":"http://med.stanford.edu/profiles/Olga_Razorenova","researchInterest":""},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development."},{"lastName":"Feldman","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Medicine - Endocrinology/Gerontology/Metab"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus (Active) Professor,Medicine - Endocrinology/Gerontology/Metab","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4315&type=small&showNoImage","displayName":"David Feldman","firstName":"David","href":"http://med.stanford.edu/profiles/David_Feldman","researchInterest":"Studies of the role of the vitamin D receptor in the action of 1,25-dihydroxyvitamin D, the active vitamin D hormone.  Current efforts are evaluating the vitamin D receptor in prostate cancer, osteoporosis and rickets."},{"lastName":"Yang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9337&type=small&showNoImage","displayName":"Qing Yang","firstName":"Qing","href":"http://med.stanford.edu/profiles/Qing_Yang","researchInterest":""}]}