{"result":[{"lastName":"Yao","clinicalFocus":[{"focus":"Fertility (Reproductive Medicine)"},{"focus":"Gynecology"},{"focus":"Reprod. Endocrinology and Infertility"}],"appointments":[{"appointment":"Assistant Professor,Obstetrics & Gynecology"}],"primaryAppointment":"Assistant Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3988&type=small&showNoImage","displayName":"Mylene W. M. Yao, M.D.","firstName":"Mylene","href":"http://med.stanford.edu/profiles/Mylene_Yao","researchInterest":"Mylene\u0092s laboratory is interested in early mammalian embryo development. We investigate genes and mechanisms that are critical in the maternal-zygotic and the morula-blastocyst transitions using experimental systems that we have established for the mouse and human embryo. Specifically, we aim to understand how key processes such as nuclear reprogramming, establishment of developmental competence, maintenance of pluripotency, and cell cycle regulation are regulated at the earliest stages."},{"lastName":"Behr","clinicalFocus":[{"focus":"Fertility (Reproductive Medicine)"},{"focus":"Obstetrics & Gynecology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Obstetrics & Gynecology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4231&type=small&showNoImage","displayName":"Barry Behr, Ph.D., H.C.L.D.","firstName":"Barry","href":"http://med.stanford.edu/profiles/Barry_Behr","researchInterest":"Development of improved embryo culture conditions in vitro. Blastocyst cultures. Embryo metabolism in vitro. Embryo maternal dialogue. Clinical application and integration of extended embryo culture systems. Monozygotic twinning. Prevention of multiple pregnancy. Sperm motility enhancers. Fluorescent and non-fluorescent markers of sperm morphology and viablility. Oocyte cryopreservation. Fertility preservation. Improving IVF outcome."},{"lastName":"Fuller","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4159&type=small&showNoImage","displayName":"Margaret T. Fuller","firstName":"Margaret","href":"http://med.stanford.edu/profiles/Margaret_Fuller","researchInterest":"Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis."},{"lastName":"Westphal","clinicalFocus":[{"focus":"Fertility (Reproductive Medicine)"},{"focus":"Gynecology"},{"focus":"Obstetrics and Gynecology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Obstetrics & Gynecology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4716&type=small&showNoImage","displayName":"Lynn Marie Westphal, MD","firstName":"Lynn","href":"http://med.stanford.edu/profiles/Lynn_Westphal","researchInterest":"Infertility, fertility preservation, oocyte cryopreservation"},{"lastName":"Wernig","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Assistant Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10445&type=small&showNoImage","displayName":"Marius Wernig","firstName":"Marius","href":"http://med.stanford.edu/profiles/Marius_Wernig","researchInterest":"Epigenetic Reprogramming, Pluripotent Stem Cells, Neural Differentiation: implications in development and regenerative medicine"},{"lastName":"Milki","clinicalFocus":[{"focus":"Fertility (Reproductive Medicine)"},{"focus":"Gynecology"},{"focus":"Obstetrics"},{"focus":"Reprod. Endocrinology and Infertility"}],"appointments":[{"appointment":"Professor - Med Center Line,Obstetrics & Gynecology"}],"primaryAppointment":"Professor - Med Center Line,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6109&type=small&showNoImage","displayName":"Amin Milki","firstName":"Amin","href":"http://med.stanford.edu/profiles/Amin_Milki","researchInterest":"Infertility \r\nAssisted Reproductive Technologies Microsurgery and Endoscopic Surgery."},{"lastName":"Chavez","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9821&type=small&showNoImage","displayName":"Shawn L. Chavez","firstName":"Shawn","href":"http://med.stanford.edu/profiles/Shawn_Chavez","researchInterest":"My current work is focused on the role of DNA Methyltransferases (DNMTs) in human germ cell differentiation and imprinting. Previous studies in rodents suggest that DNA methylation may contribute to the regulation of germ cell differentiation. Therefore, we are evaluating the expression and function of DNMTs in hESC-derived germ cells throughout development and determining their importance for normal germ cell differentiation and imprinting."},{"lastName":"Drukker","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9848&type=small&showNoImage","displayName":"Micha Drukker","firstName":"Micha","href":"http://med.stanford.edu/profiles/Micha_Drukker","researchInterest":""},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Sr Research Scholar,Center for Biomedical Ethics"}],"primaryAppointment":"Sr Research Scholar,Center for Biomedical Ethics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7245&type=small&showNoImage","displayName":"Christopher Thomas Scott","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Scott","researchInterest":"My research focuses on the political, legal, ethical and economic impacts of stem cell research.  Topics include: embryonic and adult stem cell research and clinical trials, stem cell banking, human-animal chimeras; cell and gamete donation; international perspectives of bioethics; global economic impacts; national and state regulatory policy, stem cell entrepreneurship, intellectual property and offshore stem cell transplants."},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Francke","clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome"},{"lastName":"Pollack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","displayName":"Jonathan Pollack","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Pollack","researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies."},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Statistics"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6454&type=small&showNoImage","displayName":"Wing Wong","firstName":"Wing","href":"http://med.stanford.edu/profiles/Wing_Wong","researchInterest":"Current interest centers on the application of statistics to problems arsing from biology. We are particularly interested in questions concerning gene regulation and signal transduction."},{"lastName":"Lathi","clinicalFocus":[{"focus":"Fertility (Reproductive Medicine)"},{"focus":"Recurrent Pregnancy Loss and Miscarriage"},{"focus":"Gynecology"},{"focus":"Reprod. Endocrinology and Infertility"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Obstetrics & Gynecology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4071&type=small&showNoImage","displayName":"Ruth Lathi, MD","firstName":"Ruth","href":"http://med.stanford.edu/profiles/Ruth_Lathi","researchInterest":"Recurrent miscarriage, genetic and other causes of miscarriage, preimplantation genetic diagnosis, effects of fertility treatments on androgen levels in early pregnancy and how fertility diagnosis and treatments affect pregnancy outcomes."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","displayName":"Matthew Scott","firstName":"Matthew","href":"http://med.stanford.edu/profiles/Matthew_Scott","researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size."},{"lastName":"Baker","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6206&type=small&showNoImage","displayName":"Bruce Baker","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Baker","researchInterest":""},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"Feldman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6220&type=small&showNoImage","displayName":"Marcus Feldman","firstName":"Marcus","href":"http://med.stanford.edu/profiles/Marcus_Feldman","researchInterest":""},{"lastName":"Wu","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Congenital Heart Disease (Adult)"},{"focus":"Echocardiography"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Assistant Professor - Med Center Line,Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6159&type=small&showNoImage","displayName":"Joseph  C. Wu","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Wu","researchInterest":"My lab works on biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. We use a combination of gene profiling, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo.  For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For ESC, we are currently studying their tumorigenicity, immunogenicity, and differentiation"},{"lastName":"Villeneuve","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4035&type=small&showNoImage","displayName":"Anne Villeneuve","firstName":"Anne","href":"http://med.stanford.edu/profiles/Anne_Villeneuve","researchInterest":"Mechanisms underlying homologous chromosome pairing, DNA recombination and chromosome remodeling during meiosis, using the nematode Caenorhabditis elegans as an experimental system.  High-resolution 3-D imaging of dynamic reorganization of chromosome architecture.  Role of protease inhibitors in regulating sperm activation."},{"lastName":"Petrov","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6234&type=small&showNoImage","displayName":"Dmitri Petrov","firstName":"Dmitri","href":"http://med.stanford.edu/profiles/Dmitri_Petrov","researchInterest":""},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Kingsley","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4193&type=small&showNoImage","displayName":"David Kingsley","firstName":"David","href":"http://med.stanford.edu/profiles/David_Kingsley","researchInterest":"My laboratory uses a variety of genetic, cellular, and molecular approaches to study skeletal development in humans, mice, and  fish. Many of our studies begin with naturally occuring genetic traits that alter skeletal development. By isolating the genes responsible for these traits, it has been possible to identify key pathways that control creation of skeletal tissue, repair of fractures, susceptibility to arthritis, and dramatic modifications of skeletal morphology during vertebrate evolution"}]}