{"result":[{"researchInterest":"The biochemistry and molecular genetics of growth and differentiation of nerve cells. The structure, biosynthesis and mechanism of action of nerve growth factor and other neurotrophins. Gene regulation in target organs and glial cells during nerve regeneration. The role of apolipoproteins and of the myelin protein PMP-22 during nerve degeneration and regeneration and in peripheral neuropathies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3996&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Eric_Shooter","appointments":[{"appointment":"Emeritus (Active) Professor,Neurobiology"}],"clinicalFocus":[],"firstName":"Eric","primaryAppointment":"Emeritus (Active) Professor,Neurobiology","displayName":"Eric Shooter","lastName":"Shooter"},{"researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ben_Barres","appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"clinicalFocus":[],"firstName":"Ben","primaryAppointment":"Professor,Neurobiology","displayName":"Ben Barres","lastName":"Barres"},{"researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3929&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Tony_Wyss-Coray","appointments":[{"appointment":"Associate Professor (Research),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Tony","primaryAppointment":"Associate Professor (Research),Neurology & Neurological Sciences","displayName":"Tony Wyss-Coray","lastName":"Wyss-Coray"},{"researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Craig_Garner","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Craig","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Craig C. Garner","lastName":"Garner"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6114&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Sapolsky","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor,Neurosurgery"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Robert Sapolsky","lastName":"Sapolsky"},{"researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Theo_Palmer","appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Theo","primaryAppointment":"Associate Professor,Neurosurgery","displayName":"Theo Palmer","lastName":"Palmer"},{"researchInterest":"The cellular and molecular basis for brain cell injury in stroke is our focus.  Astrocytes and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles.  We study gene therapy with heat shock proteins, changes in mitochondrial function, oxidative stress and inflammation during ischemia. We also model cell death pathways and the effects of Hsp70.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4657&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Rona_Giffard","appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Rona","primaryAppointment":"Professor,Anesthesia","displayName":"Rona Giffard","lastName":"Giffard"},{"researchInterest":"Our research focuses on understanding disease mechanisms of stroke injury and neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS) as they relate to the COX-2-prostaglandin pathways.  We are identifying prostaglandin receptor pathways that are involved in these disease models, and our objective is to identify which receptors will be translationally relevant in human neurological disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7903&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Katrin_Andreasson","appointments":[{"appointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Katrin","primaryAppointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences","displayName":"Katrin Andreasson","lastName":"Andreasson"},{"researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5928&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_McConnell","appointments":[{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Susan","primaryAppointment":"Member,Bio-X","displayName":"Susan McConnell","lastName":"McConnell"},{"researchInterest":"Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease. Pharmacogenetics of mood disorders and nicotine addiction.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Greer_Murphy","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Neurosciences"}],"clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"}],"firstName":"Greer","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Neurosciences","displayName":"Greer Murphy M.D., Ph.D.","lastName":"Murphy"},{"researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Sudhof","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Thomas Sudhof","lastName":"Sudhof"},{"researchInterest":"Our group initially identified the hypocretins, two hypothalamic neuropeptides that have a key role in maintaining the states of vigilance. We also discovered cortistatin, a peptide that modulates cortical excitability. My lab uses molecular, pharmacological, anatomical and behavioral methods to identify new roles for these transmitters. We are also interested in the cellular and molecular mechanisms by which neuronal systems integrate homeostatic information and regulate complex behaviors.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7308&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Luis_de Lecea","appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Luis","primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center","displayName":"Luis de Lecea","lastName":"de Lecea"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9345&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ben_Emery","appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"clinicalFocus":[],"firstName":"Ben","primaryAppointment":"Postdoctoral Research fellow, Neurobiology","displayName":"Ben Emery","lastName":"Emery"},{"researchInterest":"Most types of congenital and acquired hearing loss arise from damage to, or loss of hair cells, the sensory cells of the inner ear.  Our recent work has focused on generating inner ear cell types from stem cells and we are interested in signaling pathways that control hair cell and auditory neuron (re-)generation in vitro and in vivo.  In a second line of research, we are working on the identification and the molceular characterization of proteins that are important for hair cell function.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7084&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stefan_Heller","appointments":[{"appointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Associate Professor (By courtesy),Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Stefan","primaryAppointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)","displayName":"Stefan Heller","lastName":"Heller"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9630&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Olzmann","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"James Olzmann","lastName":"Olzmann"},{"researchInterest":"Development and nanoscale assembly of carbon nanotubes and related nanomaterials for electronic and energy applications.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8779&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Melburne_LeMieux","appointments":[{"appointment":"Postdoctoral Research fellow, Chemical Engineering"}],"clinicalFocus":[],"firstName":"Melburne","primaryAppointment":"Postdoctoral Research fellow, Chemical Engineering","displayName":"Melbs LeMieux","lastName":"LeMieux"},{"researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Isabella_Graef","appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Isabella","primaryAppointment":"Assistant Professor,Pathology","displayName":"Isabella Graef","lastName":"Graef"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"Neuronal death after cerebral ischemia and neural injury using transgenic strategy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4423&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Pak_Chan","appointments":[{"appointment":"Professor,Neurosurgery"}],"clinicalFocus":[],"firstName":"Pak","primaryAppointment":"Professor,Neurosurgery","displayName":"Pak H. Chan","lastName":"Chan"},{"researchInterest":"My research interests include nerve and muscle pathology, mitochondrial diseases, pediatric neurooncology, and transgenic mouse pathology.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3892&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Hannes_Vogel","appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Professor - Med Center Line (By courtesy),Neurosurgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"Hannes","primaryAppointment":"Professor - Med Center Line,Pathology","displayName":"Hannes Vogel","lastName":"Vogel"},{"researchInterest":"Dr. Ho did her PhD work in HSV pathogenesis and postdoctoral research in CNS gene therapy with viral vectors.  Her current interests are in viral and fungal infections in immunocompromised patients and her research focuses on infection complications in neutropenic patients.  In collaboration with Dr. C. Dekker of the Stanford-LPCH Vaccine Program and with Dr. J. Brown of the BMT Division, she is also conducting clinical trials on vaccines, antivirals and antifungals as a co-investigator.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7106&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Dora_Ho","appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Infectious Diseases"}],"clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"},{"focus":"Immunocompromised Host"}],"firstName":"Dora","primaryAppointment":"Clinical Assistant Professor,Medicine - Infectious Diseases","displayName":"Dora Ho","lastName":"Ho"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13416&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Manish_Butte","appointments":[{"appointment":"Assistant Professor,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Manish","primaryAppointment":"Assistant Professor,Pediatrics - Immunology & Transplant Biology","displayName":"Manish J. Butte, MD PhD","lastName":"Butte"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10602&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Asya_Rolls","appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"clinicalFocus":[],"firstName":"Asya","primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","displayName":"Asya Rolls","lastName":"Rolls"},{"researchInterest":"My laboratory focuses on understanding the transcriptional processes that govern the transformation of normal mammalian cells to neoplastic state.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zijie_Sun","appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Zijie","primaryAppointment":"Associate Professor,Urology","displayName":"Zijie Sun","lastName":"Sun"}]}