{"result":[{"lastName":"Skibbe","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8702&type=small&showNoImage","displayName":"David Skibbe","firstName":"David","href":"http://med.stanford.edu/profiles/David_Skibbe","researchInterest":""},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","displayName":"Ronald Davis","firstName":"Ronald","href":"http://med.stanford.edu/profiles/Ronald_Davis","researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion."},{"lastName":"Frommer","clinicalFocus":[],"appointments":[{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6305&type=small&showNoImage","displayName":"Wolf B. Frommer","firstName":"Wolf","href":"http://med.stanford.edu/profiles/Wolf_Frommer","researchInterest":"Watching cells at work \r\nFocus: Transport / signaling across the plasma membrane (sugars, amino acids). \r\nTools: FRET-based nanosensors for metabolite imaging (with subcellular resolution) in living organisms using confocal fluorescence microscopy and HTS; Sensor optimization by computational design; RNAi to modify cellular functions.\r\nGoals: Identify unknown sugar effluxers from liver/plant cells; study regulatory networks. \r\nModel systems: liver, neuronal, plant cell cultures, Arabidopsis, yeast"},{"lastName":"Petrov","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6234&type=small&showNoImage","displayName":"Dmitri Petrov","firstName":"Dmitri","href":"http://med.stanford.edu/profiles/Dmitri_Petrov","researchInterest":""},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Hachez","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11252&type=small&showNoImage","displayName":"Charles Hachez","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Hachez","researchInterest":""},{"lastName":"Cohen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4481&type=small&showNoImage","displayName":"Stanley N. Cohen, MD","firstName":"Stanley","href":"http://med.stanford.edu/profiles/Stanley_Cohen","researchInterest":"We study the functional and structural signals that govern mRNA decay and gene expression in bacteria, as well as mechanisms affecting aging and the ability of mammalian cells to support the propagation of viruses.  A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of gene expression on a genome-wide basis."},{"lastName":"Sarnow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4458&type=small&showNoImage","displayName":"Peter Sarnow","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Sarnow","researchInterest":"Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated."},{"lastName":"Barton","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Associate Professor (By courtesy),Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6253&type=small&showNoImage","displayName":"Kathryn Barton","firstName":"Kathryn","href":"http://med.stanford.edu/profiles/Kathryn_Barton","researchInterest":""},{"lastName":"Bergmann","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6207&type=small&showNoImage","displayName":"Dominique Bergmann","firstName":"Dominique","href":"http://med.stanford.edu/profiles/Dominique_Bergmann","researchInterest":"We use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division."},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Biochemistry"},{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus (Active) Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab\u0092s research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Cherry","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4249&type=small&showNoImage","displayName":"Mike Cherry","firstName":"JMichael","href":"http://med.stanford.edu/profiles/JMichael_Cherry","researchInterest":"The focus of my group is the application of bioinformatics to the collection and dissemination genetic, genomic and cellular  information. We abstracts the published results into our database, SGD. We explore the volumes of information that have been elucidated for the budding yeast S. cerevisiae.  My research is the applied use computers and databases: designing a resource to effectively provide biological information to the research community, and the development of the Gene Ontology."},{"lastName":"Mudgett","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6232&type=small&showNoImage","displayName":"Mary Beth Mudgett","firstName":"Mary Beth","href":"http://med.stanford.edu/profiles/Mary Beth_Mudgett","researchInterest":"My laboratory investigates how bacterial pathogens employ proteins secreted by the type III secretion system (TTSS) to manipulate eukaryotic signaling to promote disease.  We study TTSS effectors in the plant pathogen Xanthomonas campestris, the causal agent of bacterial spot disease of pepper and tomato. For these studies, we apply biochemical, cell biological, and genetic approaches using the natural hosts and two model pathosystems."},{"lastName":"Puglisi","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4431&type=small&showNoImage","displayName":"Joseph (Jody) Puglisi","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Puglisi","researchInterest":"The Puglisi group investigates the role of RNA in cellular processes and disease.  We investigate dynamics using single-molecule approaches.  Our goal is a unified picture of structure, dynamics and function.  We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections.  A long-term goal is to target processes involving RNA with novel therapeutic strategies."},{"lastName":"Francke","clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome"},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Jiang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9125&type=small&showNoImage","displayName":"Jie Jiang","firstName":"Jie","href":"http://med.stanford.edu/profiles/Jie_Jiang","researchInterest":""},{"lastName":"Hanawalt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","displayName":"Philip Hanawalt","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Hanawalt","researchInterest":"Hanawalt has been a productive researcher in the field of DNA repair since his pioneering discovery of repair replication in E. coli in 1963. He also first demonstrated repair replication in mycoplasmata and in a eukaryote and he has developed a number of important experimental approaches for studying repair, beginning with the BrdUrd density labeling method for resolving semiconservatively replicated DNA from parental DNA containing repair patches. Hanawalt\u0092s approach was used to validate the "},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Statistics"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6454&type=small&showNoImage","displayName":"Wing Wong","firstName":"Wing","href":"http://med.stanford.edu/profiles/Wing_Wong","researchInterest":"Current interest centers on the application of statistics to problems arsing from biology. We are particularly interested in questions concerning gene regulation and signal transduction."},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/Arend_Sidow","researchInterest":"We study the function and molecular evolution of proteins and noncoding functional elements in the genome.  Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Hiller","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10117&type=small&showNoImage","displayName":"Michael Hiller","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Hiller","researchInterest":""},{"lastName":"Paciorek","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9174&type=small&showNoImage","displayName":"Tomasz Paciorek","firstName":"Tomasz","href":"http://med.stanford.edu/profiles/Tomasz_Paciorek","researchInterest":""},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Tobin","clinicalFocus":[],"appointments":[{"appointment":"Member,Cancer Center"},{"appointment":"Sr Research Scholar (PI Waiver),Center for Biomedical Ethics"}],"primaryAppointment":"Member,Cancer Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6945&type=small&showNoImage","displayName":"Sara L. (Sally) Tobin","firstName":"Sara","href":"http://med.stanford.edu/profiles/Sara_Tobin","researchInterest":"Tobin is a Senior Research Scholar in the Program for Genomics, Ethics, and Society at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983, where she established her independent research l"},{"lastName":"Beachy","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7655&type=small&showNoImage","displayName":"Philip Beachy","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Beachy","researchInterest":"Function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells."}]}