{"result":[{"lastName":"Frommer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6305&type=small&showNoImage","displayName":"Wolf B. Frommer","firstName":"Wolf","href":"http://med.stanford.edu/profiles/Wolf_Frommer","researchInterest":"Watching cells at work \r\nFocus: Transport / signaling across the plasma membrane (sugars, amino acids). \r\nTools: FRET-based nanosensors for metabolite imaging (with subcellular resolution) in living organisms using confocal fluorescence microscopy and HTS; Sensor optimization by computational design; RNAi to modify cellular functions.\r\nGoals: Identify unknown sugar effluxers from liver/plant cells; study regulatory networks. \r\nModel systems: liver, neuronal, plant cell cultures, Arabidopsis, yeast"},{"lastName":"Barton","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Associate Professor (By courtesy),Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6253&type=small&showNoImage","displayName":"Kathryn Barton","firstName":"Kathryn","href":"http://med.stanford.edu/profiles/Kathryn_Barton","researchInterest":""},{"lastName":"Sosso","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37311&type=small&showNoImage","displayName":"Davide Sosso","firstName":"Davide","href":"http://med.stanford.edu/profiles/Davide_Sosso","researchInterest":""},{"lastName":"Lau","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18882&type=small&showNoImage","displayName":"On Sun Lau","firstName":"On Sun","href":"http://med.stanford.edu/profiles/On Sun_Lau","researchInterest":""},{"lastName":"Matos","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Ph.D., Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19582&type=small&showNoImage","displayName":"Juliana Matos","firstName":"Juliana","href":"http://med.stanford.edu/profiles/Juliana_Matos","researchInterest":""},{"lastName":"Mueller","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=30707&type=small&showNoImage","displayName":"Andre Mueller","firstName":"Andre","href":"http://med.stanford.edu/profiles/Andre_Mueller","researchInterest":""},{"lastName":"Mourrain","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24313&type=small&showNoImage","displayName":"Philippe Mourrain","firstName":"Philippe","href":"http://med.stanford.edu/profiles/Philippe_Mourrain","researchInterest":""},{"lastName":"Walbot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6248&type=small&showNoImage","displayName":"Virginia Walbot","firstName":"Virginia","href":"http://med.stanford.edu/profiles/Virginia_Walbot","researchInterest":"Our current focus is on maize anther development to understand how cell fate is specified.  Ultimately we want to understand how MuDR/Mu transposons of maize switch from a \"cut and paste\" biochemistry to a net replicative outcome during the life cycle.  We have discovered that frameshift translation is required to produce one form of the transposase."},{"lastName":"Elmlund","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23183&type=small&showNoImage","displayName":"Dominika Elmlund","firstName":"Dominika","href":"http://med.stanford.edu/profiles/Dominika_Elmlund","researchInterest":"I am interested in the structural biology of TFIID-dependent transcription. My investigations are focused toward determining the roles of TBP-lacking and TBP-containing TFIID states in the dynamic transcription initiation process. I am also involved in development of new computational methods for 3D structure determination from electron microscopic projection images of single-particles. The collection of algorithms developed so far constitutes a new open source software package SIMPLE (Single-p"},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=33140&type=small&showNoImage","displayName":"Taotao Chen","firstName":"TaoTao","href":"http://med.stanford.edu/profiles/TaoTao_Chen","researchInterest":""},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","researchInterest":"Chromatin regulation and its roles in human cancer and the development of the nervous system.  Engineering new methods for studying and controlling chromatin in living cells."},{"lastName":"Cooke","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Genetics"}],"primaryAppointment":"Ph.D., Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19681&type=small&showNoImage","displayName":"Thomas Cooke","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Cooke","researchInterest":""},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Falkow","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Microbiology & Immunology"},{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Professor Emeritus,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4488&type=small&showNoImage","displayName":"Stanley Falkow","firstName":"Stanley","href":"http://med.stanford.edu/profiles/Stanley_Falkow","researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu)."},{"lastName":"Bergmann","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6207&type=small&showNoImage","displayName":"Dominique Bergmann","firstName":"Dominique","href":"http://med.stanford.edu/profiles/Dominique_Bergmann","researchInterest":"We use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Cherry","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4249&type=small&showNoImage","displayName":"Mike Cherry","firstName":"J. Michael","href":"http://med.stanford.edu/profiles/J. Michael_Cherry","researchInterest":"My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education.  Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments.  The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research."},{"lastName":"Newman","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23952&type=small&showNoImage","displayName":"Aaron Newman","firstName":"Aaron","href":"http://med.stanford.edu/profiles/Aaron_Newman","researchInterest":""},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Bogyo","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3957&type=small&showNoImage","displayName":"Matthew Bogyo","firstName":"Matthew","href":"http://med.stanford.edu/profiles/Matthew_Bogyo","researchInterest":"Our lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include: \r\n\r\n1) Design and synthesis of novel chemical probes for each of the primary protease families.\r\n\r\n2) Understanding the role of proteolysis in the life cycle of the human parasites, Plasmodium falciparum and Toxoplasma gondii.\r\n\r\n3) Defining the specific functional roles of proteases during the process of tumorogenesis.\r\n\r\n4) In vivo imaging of protease activity"},{"lastName":"Ferrell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4656&type=small&showNoImage","displayName":"James Ferrell","firstName":"James","href":"http://med.stanford.edu/profiles/James_Ferrell","researchInterest":"My lab has two main goals: to understand mitotic regulation and to understand the systems-level logic of simple signaling circuits.  We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study.  We also carry out single-cell fluorescence imaging studies on mammalian cell lines.  Our experimental work is complemented by computational and theoretical studies aimed at identifying the design principles of regulatory circuits."},{"lastName":"Carette","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20464&type=small&showNoImage","displayName":"Jan Carette","firstName":"Jan","href":"http://med.stanford.edu/profiles/Jan_Carette","researchInterest":"Our research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies."}]}