{"result":[{"lastName":"Kerchner","clinicalFocus":[{"focus":"Alzheimer's Disease"},{"focus":"Mild Cognitive Impairment"},{"focus":"Dementia"},{"focus":"Behavioral Neurology"},{"focus":"Neurodegenerative Disease"},{"focus":"Neuropsychology"},{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15338&type=small&showNoImage","displayName":"Geoffrey Kerchner","firstName":"Geoffrey","href":"http://med.stanford.edu/profiles/Geoffrey_Kerchner","researchInterest":"Dr. Kerchner is a behavioral neurologist who cares for patients with Alzheimer's disease and other age-related neurodegenerative illnesses. He studies the use of ultra-high field MRI and other advanced neuroimaging technologies to reveal how these diseases affect the microscopic structure and circuitry of the brain, with the intent of creating new strategies for early diagnosis. Dr. Kerchner also supervises the participation of patients in clinical trials for Alzheimer\u0092s disease."},{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20934&type=small&showNoImage","displayName":"Lu Chen","firstName":"Lu","href":"http://med.stanford.edu/profiles/Lu_Chen","researchInterest":"What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation."},{"lastName":"Kendig","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Anesthesia"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4161&type=small&showNoImage","displayName":"Joan Kendig","firstName":"Joan","href":"http://med.stanford.edu/profiles/Joan_Kendig","researchInterest":"My laboratory tries to find out how pharmacologic agents used in the practice of anesthesia (general anesthetic and analgesic agents) lead to therapeutically desireable endpoints including unconsciousness, immobility and absence of pain. The old idea that general anesthetics are uniformly non-specific \"membrane stabilizers\" is giving way to a new realization that these agents exert specific actions on particular ion channels and intracellular signalling systems."},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"Ding","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=32293&type=small&showNoImage","displayName":"Jun Ding","firstName":"Jun","href":"http://med.stanford.edu/profiles/Jun_Ding","researchInterest":"Neural circuits of movement control in health and movement disorders"},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Barres","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","displayName":"Ben Barres","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Barres","researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system."},{"lastName":"Darian-Smith","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Comparative Medicine"}],"primaryAppointment":"Associate Professor,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5979&type=small&showNoImage","displayName":"Corinna Darian-Smith","firstName":"Corinna","href":"http://med.stanford.edu/profiles/Corinna_Darian-Smith","researchInterest":"My lab looks at the organization and function of central neural pathways that underlie directed manual behavior.  We are specifically interested in how these pathways adapt following injury, and use a combination of approaches in monkeys to identify mechanisms mediating neural reorganization and behavioral recovery."},{"lastName":"Grone","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18383&type=small&showNoImage","displayName":"Brian Grone","firstName":"Brian","href":"http://med.stanford.edu/profiles/Brian_Grone","researchInterest":""},{"lastName":"Dhabhar","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Psychosocial"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Psychosocial","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7313&type=small&showNoImage","displayName":"Firdaus Dhabhar","firstName":"Firdaus","href":"http://med.stanford.edu/profiles/Firdaus_Dhabhar","researchInterest":"Although stress has a bad reputation the fight-or-flight stress response is nature's fundamental survival system. Our laboratory elucidates mechanisms that mediate the newly appreciated immunoenhancing effects of short-term stress versus the well known immunosuppressive effects of long-term stress. We investigate stress effects on leukocyte trafficking, cytokine gene/protein expression, and innate/adaptive immunity, in preclinical & clinical models of skin immunity, vaccines, surgery, & cancer."},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Giocomo","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35065&type=small&showNoImage","displayName":"Lisa Giocomo","firstName":"Lisa","href":"http://med.stanford.edu/profiles/Lisa_Giocomo","researchInterest":"My laboratory studies the cellular and molecular mechanisms underlying the organization of cortical circuits important for spatial navigation and memory. We are particularly focused on medial entorhinal cortex, where many neurons fire in spatially specific patterns and thus offer a measurable output for molecular manipulations. We combine electrophysiology, genetic approaches and behavioral paradigms to unravel the mechanisms and behavioral relevance of non-sensory cortical organization. Our fi"},{"lastName":"Cheng","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Neurosurgery"}],"primaryAppointment":"Basic Life Science Research Associate,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8752&type=small&showNoImage","displayName":"Michelle Cheng","firstName":"Michelle","href":"http://med.stanford.edu/profiles/Michelle_Cheng","researchInterest":""},{"lastName":"Adhikari","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21125&type=small&showNoImage","displayName":"Avishek Adhikari","firstName":"Avishek","href":"http://med.stanford.edu/profiles/Avishek_Adhikari","researchInterest":""},{"lastName":"De la Herran Arita","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34617&type=small&showNoImage","displayName":"Alberto De la Herrán Arita","firstName":"Alberto","href":"http://med.stanford.edu/profiles/Alberto_De la Herran Arita","researchInterest":"Narcolepsy- hypocretin deficiency is a common sleep disorder characterized by excessive daytime sleepiness and abnormal sleep-wake patterns. These patients also suffer from cataplexy, a sudden loss of muscle tone triggered by strong emotions such as laughter. The disorder is caused by the specific loss of hypothalamic neurons producing two hypocretin peptides with high homology with each other, namely hcrt1 and hcrt2.  These are produced by proteolytic cleavage of a single precursor protein kno"},{"lastName":"Lindley","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Psychiatry & Behavioral Science - Stanford/VA Aging Clinical Research Center"}],"primaryAppointment":"Assistant Professor - Med Center Line,Psychiatry & Behavioral Science - Stanford/VA Aging Clinical Research Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6056&type=small&showNoImage","displayName":"Steven Lindley","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Lindley","researchInterest":"Maximizing the use of evidence-based practices and reducing unnecessary medical burden of psychiatric treatments for stress-related disorders."},{"lastName":"Devarajan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19830&type=small&showNoImage","displayName":"Sridharan Devarajan","firstName":"Sridharan","href":"http://med.stanford.edu/profiles/Sridharan_Devarajan","researchInterest":"Attention allows us to selectively process the most important information in the sensory environment. I study how gamma-band (25-140Hz) oscillations that occur in brain circuits during attention shape behavior. I study the mechanisms and role of these oscillations in the optic tectum (superior colliculus), a midbrain structure involved in attention, sensory processing and gaze control, using a combination of recordings in live animals, in brain slices, and computational modeling."},{"lastName":"Schatzberg","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4194&type=small&showNoImage","displayName":"Alan F. Schatzberg","firstName":"Alan","href":"http://med.stanford.edu/profiles/Alan_Schatzberg","researchInterest":"Biological bases of depressive disorders;, glucocorticoid/dopamine interactions in delusional depression;, pharmacologic treatment of depressive disorders."},{"lastName":"Shatz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8146&type=small&showNoImage","displayName":"Carla Shatz","firstName":"Carla","href":"http://med.stanford.edu/profiles/Carla_Shatz","researchInterest":"The goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory."},{"lastName":"de Lecea","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7308&type=small&showNoImage","displayName":"Luis de Lecea","firstName":"Luis","href":"http://med.stanford.edu/profiles/Luis_de Lecea","researchInterest":"My lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction."}]}