{"result":[{"lastName":"Falkow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Professor,Medicine"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4488&type=small&showNoImage","displayName":"Stanley Falkow","firstName":"Stanley","href":"http://med.stanford.edu/profiles/Stanley_Falkow","researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu)."},{"lastName":"Tompkins","clinicalFocus":[{"focus":"Infectious Diseases"},{"focus":"Internal Medicine"},{"focus":"hospital epidemiology"}],"appointments":[{"appointment":"Professor,Medicine - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4603&type=small&showNoImage","displayName":"Lucy Tompkins","firstName":"Lucy","href":"http://med.stanford.edu/profiles/Lucy_Tompkins","researchInterest":"Molecular and cellular pathogenesis of Helicobacter infection. Molecular epidemiology, hospital epidemiology."},{"lastName":"Parsonnet","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"}],"appointments":[{"appointment":"Professor,Medicine - Infectious Diseases"},{"appointment":"Professor,Health Research & Policy"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4495&type=small&showNoImage","displayName":"Julie Parsonnet","firstName":"Julie","href":"http://med.stanford.edu/profiles/Julie_Parsonnet","researchInterest":"I am interested in the long-term consequences of chronic interactions between the human host and the microbial world.  Recently, we have focused most heavily on Helicobacter pylori, tuberculosis and helminth infections.  I also remain strongly interested in diarrheal diseases, particularly in the developing world, and in sanitation and hygiene."},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Associate Professor,Microbiology & Immunology"}],"primaryAppointment":"Associate Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://med.stanford.edu/profiles/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Pride","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9162&type=small&showNoImage","displayName":"David Pride","firstName":"David","href":"http://med.stanford.edu/profiles/David_Pride","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Botham","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9638&type=small&showNoImage","displayName":"Crystal M. Botham, Ph.D.","firstName":"Crystal","href":"http://med.stanford.edu/profiles/Crystal_Botham","researchInterest":""},{"lastName":"Holgado-Madruga","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurosurgery"}],"primaryAppointment":"Instructor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7072&type=small&showNoImage","displayName":"Marina Holgado-Madruga","firstName":"Maria","href":"http://med.stanford.edu/profiles/Maria_Holgado-Madruga","researchInterest":""},{"lastName":"Sibley","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4113&type=small&showNoImage","displayName":"Richard Sibley","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Sibley","researchInterest":"Immunologic mechanism of rejection in humans and animal, models of organ transplantation; histological definition of clinical pathology studies of various renal disorders."},{"lastName":"Marinkovich","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4217&type=small&showNoImage","displayName":"M. Peter Marinkovich","firstName":"Matt","href":"http://med.stanford.edu/profiles/Matt_Marinkovich","researchInterest":"The Marinkovich lab studies the function of epithelial extracellular matrix molecules, including integrins, collagens and laminins in epithelial development and carcinoma progression.  We apply our discoveries in this area towards development of molecular therapies for carcinomas, hair disease and inherited epithelial adhesive disorders."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Pachynski","clinicalFocus":[{"focus":"Genitourinary Cancer"},{"focus":"Oncology"}],"appointments":[{"appointment":"Instructor,Medicine - Oncology"},{"appointment":"Postdoctoral Medical fellow, School of Medicine"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9589&type=small&showNoImage","displayName":"Russell K Pachynski, MD","firstName":"Russell","href":"http://med.stanford.edu/profiles/Russell_Pachynski","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells."},{"lastName":"Phillips","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9437&type=small&showNoImage","displayName":"Neil Phillips","firstName":"Neil","href":"http://med.stanford.edu/profiles/Neil_Phillips","researchInterest":""},{"lastName":"Relman","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"}],"appointments":[{"appointment":"Professor,Medicine - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4005&type=small&showNoImage","displayName":"David A. Relman","firstName":"David","href":"http://med.stanford.edu/profiles/David_Relman","researchInterest":"My investigative program focuses on human-microbe interactions and human microbial ecology, and is divided into two research areas: 1) Ecology of human indigenous microbial communities; 2) Classification of humans and non-human primates with systemic infectious diseases, based on features of genome-wide gene transcript abundance patterns."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Weis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","displayName":"William Weis","firstName":"William","href":"http://med.stanford.edu/profiles/William_Weis","researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion."},{"lastName":"Mohamed Nour Mohamed Arfan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11452&type=small&showNoImage","displayName":"Adel M. Nour","firstName":"Adel","href":"http://med.stanford.edu/profiles/Adel_Mohamed Nour Mohamed Arfan","researchInterest":""},{"lastName":"Myers","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Medicine - Nephrology"}],"primaryAppointment":"Emeritus (Active) Professor,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4332&type=small&showNoImage","displayName":"Bryan Myers","firstName":"Bryan","href":"http://med.stanford.edu/profiles/Bryan_Myers","researchInterest":"A novel approach is used to evaluate glomerular disease in humans, and its progression.  A combination of physiologic techniques, a morphometric analysis of glomeruli obtained by biopsy, and mathematical modeling of glomerular ultrafiltration is used to quantify the extent of glomerular injury in humans for the first time."},{"lastName":"Khavari","clinicalFocus":[],"appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4683&type=small&showNoImage","displayName":"Paul A. Khavari, MD, PhD","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Khavari","researchInterest":"We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues."},{"lastName":"Butcher","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4498&type=small&showNoImage","displayName":"Eugene Butcher","firstName":"Eugene","href":"http://med.stanford.edu/profiles/Eugene_Butcher","researchInterest":"Our interests include: \r\n1) The physiology and significance of lymphocyte homing in local and systemic immunity; \r\n2) biochemical and genetic studies of molecules that direct leukocyte recruitment; \r\n3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; \r\n4) vascular differentiation in normal and pathologic inflammatory states; \r\n5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs."},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Monack","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Microbiology & Immunology"}],"primaryAppointment":"Assistant Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8324&type=small&showNoImage","displayName":"Denise M. Monack","firstName":"Denise","href":"http://med.stanford.edu/profiles/Denise_Monack","researchInterest":"The primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis.  We use two model systems, Salmonella typhimurium and Francisella tularensis, to study the complex host-pathogen interactions.  Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response and how F. tularensis, a stealth invader, can cause a rapid, lethal infection."},{"lastName":"Covert","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7986&type=small&showNoImage","displayName":"Markus Covert","firstName":"Markus","href":"http://med.stanford.edu/profiles/Markus_Covert","researchInterest":"Our focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors."},{"lastName":"Shen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9376&type=small&showNoImage","displayName":"Aimee Shen","firstName":"Aimee","href":"http://med.stanford.edu/profiles/Aimee_Shen","researchInterest":""}]}