{"result":[{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10051&type=small&showNoImage","displayName":"Fengling Liu","firstName":"Fengling","href":"http://med.stanford.edu/profiles/Fengling_Liu","researchInterest":""},{"lastName":"Efron","clinicalFocus":[],"appointments":[{"appointment":"Professor,Statistics"},{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6090&type=small&showNoImage","displayName":"Bradley Efron","firstName":"Bradley","href":"http://med.stanford.edu/profiles/Bradley_Efron","researchInterest":"Theories of inference applied to biostatistical data;, the bootstrap method."},{"lastName":"Khavari","clinicalFocus":[],"appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4683&type=small&showNoImage","displayName":"Paul A. Khavari, MD, PhD","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Khavari","researchInterest":"We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues."},{"lastName":"Zolopa","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Infectious Diseases"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4034&type=small&showNoImage","displayName":"Andrew Zolopa","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Zolopa","researchInterest":"Dr. Zolopa\u0092s research applies a variety of clinical epidemiologic methods in an effort to optimize antiretroviral therapy and understand the impact of drug resistance on response to ARV.   Areas of focus include the clinical application of resistance testing in optimizing antiretroviral therapy, clinical cohort and trials of antiretroviral therapies and population-based epidemiologic evaluation of HIV resistance and efficacy of ARV therapy in urban poor communities of San Francisco."},{"lastName":"Das","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Clinical Instructor,Psychiatry & Behavioral Science - Behavioral Medicine"}],"primaryAppointment":"Clinical Instructor,Psychiatry & Behavioral Science - Behavioral Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7583&type=small&showNoImage","displayName":"Bibi Das","firstName":"Bibi","href":"http://med.stanford.edu/profiles/Bibi_Das","researchInterest":"Obsessive Compulsive Disorder and Impulse Control Disorder"},{"lastName":"Shafer","clinicalFocus":[{"focus":"Infectious Disease"}],"appointments":[{"appointment":"Associate Professor (Research),Medicine - Infectious Diseases"},{"appointment":"Associate Professor (Research) (By courtesy),Pathology"}],"primaryAppointment":"Associate Professor (Research),Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4054&type=small&showNoImage","displayName":"Robert W. Shafer","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Shafer","researchInterest":"Dr Shafer's research is on the mechanisms and consequences of HIV evolution with an emphasis on HIV drug resistance. He maintains an online database (http://hivdb.stanford.edu) designed to provide a publicly available resource for those performing HIV drug resistance surveillance, interpreting HIV drug resistance tests, and developing new antiretroviral drugs."},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Attardi","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3851&type=small&showNoImage","displayName":"Laura Attardi","firstName":"Laura","href":"http://med.stanford.edu/profiles/Laura_Attardi","researchInterest":"Our research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse."},{"lastName":"Hu","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Clinical Associate Professor,Psychiatry & Behavioral Science - Psychopharmacology"}],"primaryAppointment":"Clinical Associate Professor,Psychiatry & Behavioral Science - Psychopharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4387&type=small&showNoImage","displayName":"Rona Hu","firstName":"Rona","href":"http://med.stanford.edu/profiles/Rona_Hu","researchInterest":""},{"lastName":"Lipsick","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4244&type=small&showNoImage","displayName":"Joseph (Joe) Lipsick","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Lipsick","researchInterest":"Function and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Brugmann","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9172&type=small&showNoImage","displayName":"Samantha Brugmann","firstName":"Samantha","href":"http://med.stanford.edu/profiles/Samantha_Brugmann","researchInterest":"Craniofacial development and  patterning"},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","displayName":"Chris Garcia","firstName":"Chris","href":"http://med.stanford.edu/profiles/Chris_Garcia","researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches."},{"lastName":"Glick","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Professor - Med Center Line,Psychiatry & Behavioral Science - Psychopharmacology"}],"primaryAppointment":"Professor - Med Center Line,Psychiatry & Behavioral Science - Psychopharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4238&type=small&showNoImage","displayName":"Ira D Glick","firstName":"Ira","href":"http://med.stanford.edu/profiles/Ira_Glick","researchInterest":"Schizophrenia is one of the major public health problems in American medicine. Treatment is partially efficacious but unsatisfactory. Accordingly, our research focuses on treatment outcome in two areas; finding more effective medications which have less side effects than current medications, and in the effects of combining medication with psychosocial interventions."},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Gozani","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6423&type=small&showNoImage","displayName":"Or Gozani","firstName":"Or","href":"http://med.stanford.edu/profiles/Or_Gozani","researchInterest":"We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease.  Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes.  We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9203&type=small&showNoImage","displayName":"Jonghyeob Lee","firstName":"Jonghyeob","href":"http://med.stanford.edu/profiles/Jonghyeob_Lee","researchInterest":""},{"lastName":"Kohler","clinicalFocus":[],"appointments":[{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Member,Cancer Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4019&type=small&showNoImage","displayName":"Sabine Kohler","firstName":"Sabine","href":"http://med.stanford.edu/profiles/Sabine_Kohler","researchInterest":"Translational research and clinicopathologic studies of cutaneous disease with an emphasis on cutaneous lymphomas."},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Levitt","researchInterest":"Is it possible to understand the molecular structure and function of proteins and nucleic acids in enough detail to make accurate predictions about structure and function? We are mounting a two-pronged attack on this problem using both molecular dynamics simulation and molecular modeling."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Katzenstein","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Infectious Diseases"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4325&type=small&showNoImage","displayName":"David Katzenstein","firstName":"David","href":"http://med.stanford.edu/profiles/David_Katzenstein","researchInterest":"Treatment and evaluation of HIV infectionin the United States and Europe through the AIDS Clinical Trials Group (ACTG). International HIV pathogenesis work includes studies in Zimbabwe, South Africa, and India where we are particularly interested in the pandemic of subtype C HIV-1, TB and other co-infections. The lab currently is focused on drug resistance, envelope tropism and the pathogenesis of HIV."},{"lastName":"Weis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","displayName":"William Weis","firstName":"William","href":"http://med.stanford.edu/profiles/William_Weis","researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion."},{"lastName":"Patterson","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Medicine"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3975&type=small&showNoImage","displayName":"Bruce Patterson","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Patterson","researchInterest":"Our laboratory focuses on host-viral interactions in the sexual and mother-to-child transmission of HIV-1. We developed human organotypic models to closely mimic in vivo infection. Our recent work has focused on developing immune-based and small molecule inhibitors of HIV-1 transmission."},{"lastName":"Oro","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Skin Cancer "},{"focus":"Hair disorders"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4693&type=small&showNoImage","displayName":"Anthony Oro  MD/PhD","firstName":"Anthony","href":"http://med.stanford.edu/profiles/Anthony_Oro","researchInterest":"Hedgehog signaling has been implicated in the induction or maintenance of up to 25% of human tumors and a variety of birth defects.  Our lab studies Sonic hedgehog (Shh) signaling in normal hair follicle development and in the pathogenesis of the most common human tumor, basal cell carcinoma (BCCs) of the skin.  We are interested in how the local stromal environment regulates hedgehog signaling and hair follicle or tumor growth and invasion."}]}