{"result":[{"researchInterest":"Neuronal death after cerebral ischemia and neural injury using transgenic strategy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4423&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Pak_Chan","appointments":[{"appointment":"Professor,Neurosurgery"}],"clinicalFocus":[],"firstName":"Pak","primaryAppointment":"Professor,Neurosurgery","displayName":"Pak H. Chan","lastName":"Chan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6114&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Sapolsky","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor,Neurosurgery"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Robert Sapolsky","lastName":"Sapolsky"},{"researchInterest":"Our laboratory investigates the pathophysiology and treatment of acute cerebral ischemia, as well as methods to restore neurologic function after stroke. Treatment strategies include mild brain hypothermia, gene transfer therapy and stem cell transplantation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating patients with difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4646&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Gary_Steinberg","appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurological Surgery"},{"focus":"Neurosurgery"},{"focus":"Neurosurgery, Pediatric"}],"firstName":"Gary","primaryAppointment":"Professor,Neurosurgery","displayName":"Gary Steinberg","lastName":"Steinberg"},{"researchInterest":"Dr. Ho did her PhD work in HSV pathogenesis and postdoctoral research in CNS gene therapy with viral vectors.  Her current interests are in viral and fungal infections in immunocompromised patients and her research focuses on infection complications in neutropenic patients.  In collaboration with Dr. C. Dekker of the Stanford-LPCH Vaccine Program and with Dr. J. Brown of the BMT Division, she is also conducting clinical trials on vaccines, antivirals and antifungals as a co-investigator.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7106&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Dora_Ho","appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Infectious Diseases"}],"clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"},{"focus":"Immunocompromised Host"}],"firstName":"Dora","primaryAppointment":"Clinical Assistant Professor,Medicine - Infectious Diseases","displayName":"Dora Ho","lastName":"Ho"},{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"Our research focuses on understanding disease mechanisms of stroke injury and neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS) as they relate to the COX-2-prostaglandin pathways.  We are identifying prostaglandin receptor pathways that are involved in these disease models, and our objective is to identify which receptors will be translationally relevant in human neurological disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7903&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Katrin_Andreasson","appointments":[{"appointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Katrin","primaryAppointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences","displayName":"Katrin Andreasson","lastName":"Andreasson"},{"researchInterest":"My interests lie on the glia reactivity and proliferation with aging after focal ischemic injury. Some aims are proposed:\r\n* Role of astrocyte and microglia impairment in focal ischemia;\r\n\r\nand\r\n\r\n* Gene therapy for stroke with superoxide dismutase 2.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11191&type=small&showNoImage","href":"http://med.stanford.edu/profiles/George_Barreto","appointments":[{"appointment":"Postdoctoral Research fellow, Anesthesia"}],"clinicalFocus":[],"firstName":"George","primaryAppointment":"Postdoctoral Research fellow, Anesthesia","displayName":"George Barreto","lastName":"Barreto"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6712&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Valerie_Chock","appointments":[{"appointment":"Instructor,Pediatrics - Neonatology"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"}],"firstName":"Valerie","primaryAppointment":"Instructor,Pediatrics - Neonatology","displayName":"Valerie Chock","lastName":"Chock"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9626&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jian_Luo","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Jian","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Jian Luo","lastName":"Luo"},{"researchInterest":"We are studying the mechanism of protein kinase C-mediated signal transduction in several disease models. Based on our recent data, we proposed a working hypothesis that activated PKC isozymes bind to intracellular receptor proteins located at different subcellular sites, and that these receptors differentially bind specific PKC isozymes.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Daria_Mochly-Rosen","appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Daria","primaryAppointment":"Professor,Chemical and Systems Biology","displayName":"Daria Mochly-Rosen","lastName":"Mochly-Rosen"},{"researchInterest":"MR physics into tissue contrast mechanisms such as diffusion, perfusion, and functional imaging describes the research direction. Applications of cerebral stroke (brain attacks) and neurocognitive disorders are also being developed from these methods","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4240&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Moseley","appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Professor,Radiology - Diagnostic Radiology","displayName":"Michael Moseley","lastName":"Moseley"},{"researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Nicholas_Denko","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Nicholas","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Biology","displayName":"Nicholas Denko","lastName":"Denko"},{"researchInterest":"We study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3930&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ting-Ting_Huang","appointments":[{"appointment":"Associate Professor (Research),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Ting-Ting","primaryAppointment":"Associate Professor (Research),Neurology & Neurological Sciences","displayName":"Ting-Ting Huang","lastName":"Huang"},{"researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Theo_Palmer","appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Theo","primaryAppointment":"Associate Professor,Neurosurgery","displayName":"Theo Palmer","lastName":"Palmer"},{"researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Craig_Garner","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Craig","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Craig C. Garner","lastName":"Garner"},{"researchInterest":"The long term goal  of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether  reengineering chaperone networks can provide therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6222&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Judith_Frydman","appointments":[{"appointment":"Associate Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Judith","primaryAppointment":"Associate Professor,Biology (School of Humanities and Sciences)","displayName":"Judith Frydman","lastName":"Frydman"},{"researchInterest":"Dr. Dodd is involved in clinical trials using endovascular coils that have a fiber coating that help heal aneurysms of the neck and can prevent an aneurysm from reforming. He uses minimally invasive endoscopic techniques to treat brain tumors.\r\n\r\nDodd's research interests are in cerebral blood vessel reactivity and stroke.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6790&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Dodd","appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurosurgery"},{"appointment":"Assistant Professor - Med Center Line,Radiology"}],"clinicalFocus":[{"focus":"Interventional Neuroradiology"},{"focus":"Neurosurgery"}],"firstName":"Robert","primaryAppointment":"Assistant Professor - Med Center Line,Neurosurgery","displayName":"Robert Dodd","lastName":"Dodd"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9630&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Olzmann","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"James Olzmann","lastName":"Olzmann"},{"researchInterest":"Critical Care Medicine,\r\nCardiovascular Pharmacology,\r\nAdrenergic Receptors,\r\nCongestive Heart Failure,\r\nVascular Biology,\r\nCardiopulmonary Physiology,\r\nSepsis","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6059&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Andrew_Patterson","appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Surgery"}],"clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care Medicine"}],"firstName":"Andrew","primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","displayName":"Andrew J. Patterson, M.D., Ph.D.","lastName":"Patterson"},{"researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Malenka","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Robert Malenka","lastName":"Malenka"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8914&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kristian_Doyle","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Kristian","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Kristian Doyle","lastName":"Doyle"},{"researchInterest":"chemoprevetion, HDAC inhibitors, miRNAs, tumor suppressor genes","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10537&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Emily_Noonan","appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"clinicalFocus":[],"firstName":"Emily","primaryAppointment":"Postdoctoral Research fellow, Medicine","displayName":"Emily Noonan Ph.D.","lastName":"Noonan"},{"researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3929&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Tony_Wyss-Coray","appointments":[{"appointment":"Associate Professor (Research),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Tony","primaryAppointment":"Associate Professor (Research),Neurology & Neurological Sciences","displayName":"Tony Wyss-Coray","lastName":"Wyss-Coray"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8537&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Wei","appointments":[{"appointment":"Instructor,Pediatrics - Hematology/Oncology"},{"appointment":"Postdoctoral Medical fellow, Pediatrics"}],"clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"firstName":"Michael","primaryAppointment":"Instructor,Pediatrics - Hematology/Oncology","displayName":"Michael Wei, MD, PhD","lastName":"Wei"}]}