{"result":[{"researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Edgar_Engleman","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Edgar","primaryAppointment":"Professor,Pathology","displayName":"Edgar Engleman","lastName":"Engleman"},{"researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Shoshana_Levy","appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Shoshana","primaryAppointment":"Professor (Research),Medicine - Oncology","displayName":"Shoshana Levy","lastName":"Levy"},{"researchInterest":"My research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5929&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Yasodha_Natkunam","appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematopathology"},{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"Yasodha","primaryAppointment":"Associate Professor - Med Center Line,Pathology","displayName":"Yasodha Natkunam, M.D., Ph.D","lastName":"Natkunam"},{"researchInterest":"The research in my laboratory involves the application of monoclonal and polyclonal antibodies and a variety of immunohistochemical methods to study human B-cell, T-cell, accessory cell and related neoplasms.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3786&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Roger_Warnke","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Roger","primaryAppointment":"Professor,Pathology","displayName":"Roger Warnke","lastName":"Warnke"},{"researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4138&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Negrin","appointments":[{"appointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"firstName":"Robert","primaryAppointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation","displayName":"Robert Negrin","lastName":"Negrin"},{"researchInterest":"Our interests in clude 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, and 3) the role of radiation in tumor vaccine strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4699&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_Knox","appointments":[{"appointment":"Associate Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Radiation Therapy"}],"firstName":"Susan","primaryAppointment":"Associate Professor,Radiation Oncology - Radiation Therapy","displayName":"Susan Knox","lastName":"Knox"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Daniel_Arber","appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Daniel","primaryAppointment":"Professor - Med Center Line,Pathology","displayName":"Daniel A. Arber, M.D.","lastName":"Arber"},{"researchInterest":"Clinical investigation of bone marrow and peripheral blood progenitor cell transplantation for lymphoproliferative disease and solid tumors; immunotherapy following high-dose therapy and transplantation; supportive care following transplantation; immune system reconstitution.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4547&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Keith_Stockerl-Goldstein","appointments":[{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Keith","primaryAppointment":"Member,Cancer Center","displayName":"Keith Stockerl-Goldstein, M.D.","lastName":"Stockerl-Goldstein"},{"researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Samuel_Strober","appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"firstName":"Samuel","primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","displayName":"Samuel Strober","lastName":"Strober"},{"researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Leonore","primaryAppointment":"Professor (Research),Genetics","displayName":"Leonore A. Herzenberg","lastName":"Herzenberg"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"},{"researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Cleary","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Professor,Pathology","displayName":"Michael Cleary","lastName":"Cleary"},{"researchInterest":"I work as a diagnostic surgical pathologist doing tissue and cDNA microarray-based translational research in renal neoplasia and medical renal disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4038&type=small&showNoImage","href":"http://med.stanford.edu/profiles/John_Higgins","appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"John","primaryAppointment":"Associate Professor - Med Center Line,Pathology","displayName":"John Higgins","lastName":"Higgins"},{"researchInterest":"My research is focused on attaining a better understanding of the initiation, maintenance, and progression of lymphoid tumors, and their response to immunochemotherapy toward improving current treatment strategies.  \r\n\r\nIn this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.  I hope to apply this knowledge towards the design of clinical trials in the treatment of patients with lymphoma, leukemia, and myeloma.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9558&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Arash_Alizadeh","appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"clinicalFocus":[],"firstName":"Arash","primaryAppointment":"Instructor,Medicine - Oncology","displayName":"Ash A. Alizadeh, MD/PhD","lastName":"Alizadeh"},{"researchInterest":"Hematology/Oncology, treatment of sarcomas of bone and soft tissue, biology of acute lymphoblastic leukemias, treatment of non-Hodgkin's lymphoma and Hodgkin's disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4631&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Link","appointments":[{"appointment":"Professor,Pediatrics - Hematology/Oncology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"firstName":"Michael","primaryAppointment":"Professor,Pediatrics - Hematology/Oncology","displayName":"Michael Link","lastName":"Link"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7405&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Sunil_Reddy","appointments":[{"appointment":"Clinical Instructor,Medicine - Oncology"}],"clinicalFocus":[{"focus":"lymphoma/melanoma/cutaneouslymphoma"},{"focus":"Medical Oncology"}],"firstName":"Sunil","primaryAppointment":"Clinical Instructor,Medicine - Oncology","displayName":"Sunil Reddy","lastName":"Reddy"},{"researchInterest":"As medical director of the Hematology Laboratory, my main focus is service work, including laboratory administration, bone marrow pathology, and flow cytometry interpretation. Publications arise primarily from development or evaluation of laboratory methods or collections of unusual patient cases.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4109&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Phyllis_Cornbleet","appointments":[{"appointment":"Emeritus (Active) Associate Professor,Pathology"}],"clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"Phyllis","primaryAppointment":"Emeritus (Active) Associate Professor,Pathology","displayName":"Phyllis Cornbleet","lastName":"Cornbleet"},{"researchInterest":"Clinical Interests: Hodgkin's disease and non-Hodgkin's lymphoma. Research Interests: clinical trials in Hodgkin's disease and malignant lymphoma including high dose therapy and autografting, complications of cytotoxic therapy, novel therapeutics, and clinicopathologic correlations.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4106&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Sandra_Horning","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Oncology"}],"clinicalFocus":[{"focus":"Burkitt's Lymphoma"},{"focus":"Burkitt's Lymphoma - Hematology"},{"focus":"Burkitt's Lymphoma - Medical Oncology"},{"focus":"Hodgkin's Disease - Blood and Marrow Transplant"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Leptommeningeal Disease"},{"focus":"Leptommeningeal Disease - Medical Oncology"},{"focus":"Non-Hodgkin's Lymphoma"},{"focus":"Non-Hodgkin's Lymphoma - Blood and Marrow Transplant"},{"focus":"Non-Hodgkin's Lymphoma - Medical Oncology"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Sandra","primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Oncology","displayName":"Sandra Horning","lastName":"Horning"},{"researchInterest":"My research interest is on immunotherapy of cancer. I have studies the mechanism of monoclonal antibody therapy of patients with lymphoma and am currently working on designing the next generation of engineered anti-tumor antibody based on the known mechanism to overcome resistance. I am also interested in tumor vaccine and plan to devise a novel strategy to use antibody-coated tumor cells/dendritic cells as a therpeutic vaccine.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5871&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Wen-Kai_Weng","appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Division: Blood and  \r\nMarrow Transplantation"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Cutaneous T-Cell Lymphoma"},{"focus":"Medical Oncology"}],"firstName":"Wen-Kai","primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Division: Blood and  \r\nMarrow Transplantation","displayName":"Wen-Kai Weng, MD, PhD","lastName":"Weng"},{"researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jane_Parnes","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jane","primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","displayName":"Jane Parnes","lastName":"Parnes"},{"researchInterest":"Understanding the biology of cancer-T cell interactions.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4564&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Peter_Lee","appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematology"},{"focus":"Leukemia - Hematology"}],"firstName":"Peter","primaryAppointment":"Associate Professor,Medicine - Hematology","displayName":"Peter P. Lee","lastName":"Lee"},{"researchInterest":"Allogeneic and autologous bone marrow transplantation (experimental and clinical) as a treatment modality for leukemia, lymphoma, Hodgkin's disease, multiple myeloma, hereditary disorders, immune defects and selective solid tumors. Development of novel preparatory regimens to prevent the recurrence of the underlying malignancies. Studies for the prevention of acute and chronic graft-versus-host disease. Testing of new anti-viral agents to prevent or treat viral infections.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4180&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Karl_Blume","appointments":[{"appointment":"Emeritus (Active) Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Karl","primaryAppointment":"Emeritus (Active) Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation","displayName":"Karl Blume","lastName":"Blume"},{"researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Irving_Weissman","appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Irving","primaryAppointment":"Professor,Pathology - Stem Cell Institute","displayName":"Irving Weissman","lastName":"Weissman"},{"researchInterest":"My research is in applied statistics and biostatistics. I specialize in \u000bcomputer-intensive methods for regression and classification, bootstrap, cross-validation\u000band statistical inference, and signal and image analysis for medical diagnosis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4688&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Tibshirani","appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Professor,Statistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Health Research & Policy - Biostatistics","displayName":"Robert Tibshirani","lastName":"Tibshirani"}]}