{"result":[{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic radiosurgery for GI maligancies","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4729&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Albert_Koong","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Colorectal Cancer - Radiation Oncology"},{"focus":"Esophageal Cancer"},{"focus":"Esophageal Cancer - Radiation Oncology"},{"focus":"Liver Cancer"},{"focus":"Liver Cancer - Radiation Oncology"},{"focus":"Pancreatic Cancer "},{"focus":"Pancreatic Cancer - Radiation Oncology"},{"focus":"Radiation Oncology"},{"focus":"Rectal Cancer "},{"focus":"Rectal Cancer - Radiation Oncology"},{"focus":"Stomach Cancer "},{"focus":"Stomach Cancer - Radiation Oncology"}],"firstName":"Albert","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Therapy","displayName":"Albert Koong","lastName":"Koong"},{"researchInterest":"Research Interests: cancer pharmacology, mechanisms of resistance to anticancer drugs, regulation and function of MDR1 and tubulin genes, clinical trials of modulation of drug resistance, general oncology, Phase I trials of new drugs, gene expression profiling of cancers","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4131&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Branimir_Sikic","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Medical Oncology"},{"focus":"New Drug Studies"}],"firstName":"Branimir","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Branimir I. Sikic, M. D.","lastName":"Sikic"},{"researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Nicholas_Denko","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Nicholas","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Biology","displayName":"Nicholas Denko","lastName":"Denko"},{"researchInterest":"Our interests in clude 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, and 3) the role of radiation in tumor vaccine strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4699&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_Knox","appointments":[{"appointment":"Associate Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Radiation Therapy"}],"firstName":"Susan","primaryAppointment":"Associate Professor,Radiation Oncology - Radiation Therapy","displayName":"Susan Knox","lastName":"Knox"},{"researchInterest":"My laboratory research interest focusses on the identification of serum markers for tumor hypoxia and for prognosis in patients with head and neck or lung cancers. I am also conducting a number of clinical trials specifically in patients with these tumors.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4003&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Quynh-Thu_Le","appointments":[{"appointment":"Professor - Med Center Line,Radiation Oncology - Radiation Therapy"},{"appointment":"Professor - Med Center Line (By courtesy),Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Head and Neck Cancers"},{"focus":"Head and Neck Cancers - Radiation Oncology"},{"focus":"Larynx Cancer "},{"focus":"Larynx Cancer - Radiation Oncology"},{"focus":"Lung Cancer - Radiation Oncology"},{"focus":"Oral Cavity Cancer  "},{"focus":"Oral Cavity Cancer - Radiation Oncology"},{"focus":"Radiation Oncology"},{"focus":"Salivary Gland Tumors"},{"focus":"Salivary Gland Tumors - Radiation Oncology"},{"focus":"Sarcomas - Soft Tissue "},{"focus":"Sarcomas - Soft Tissue - Radiation Oncology"},{"focus":"Skull Base Tumors "},{"focus":"Skull Base Tumors - Radiation Oncology"}],"firstName":"Quynh-Thu","primaryAppointment":"Professor - Med Center Line,Radiation Oncology - Radiation Therapy","displayName":"Quynh-Thu Le","lastName":"Le"},{"researchInterest":"Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA\u000bdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Ford","appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Associate Professor (By courtesy),Pediatrics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Cancer Genetics"},{"focus":"Gastrointestinal Cancers - Genetics"},{"focus":"Gastrointestinal Cancers - Medical Oncology"},{"focus":"Breast Cancer - Genetics"},{"focus":"Ovarian Cancer - Genetics"},{"focus":"Medical Oncology"}],"firstName":"James","primaryAppointment":"Associate Professor,Medicine - Oncology","displayName":"James Ford","lastName":"Ford"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"Our laboratory focuses on understanding how cells respond to DNA damage. Our research currently involves areas that interact with each other: repair of radiation damage, and transcriptional responses to DNA damage.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4149&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Gilbert_Chu","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Oncology"}],"firstName":"Gilbert","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Gilbert Chu","lastName":"Chu"},{"researchInterest":"Clinical expertise in GI cancers with research which emphasizes Phase I and II clinical trials of novel therapies but also includes translational studies including biomarkers, molecular imaging, tumor immunology and development of immunotherapeutic trials.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4644&type=small&showNoImage","href":"http://med.stanford.edu/profiles/George_Fisher","appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"George","primaryAppointment":"Associate Professor - Med Center Line,Medicine - Oncology","displayName":"George A. Fisher Jr.","lastName":"Fisher"},{"researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Clarke","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Michael","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Michael F. Clarke, M.D.","lastName":"Clarke"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ronald_Davis","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Ronald","primaryAppointment":"Professor,Biochemistry","displayName":"Ronald Davis","lastName":"Davis"},{"researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Uta_Francke","appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"firstName":"Uta","primaryAppointment":"Professor,Genetics","displayName":"Uta Francke","lastName":"Francke"},{"researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jonathan_Pollack","appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jonathan","primaryAppointment":"Associate Professor,Pathology","displayName":"Jonathan Pollack","lastName":"Pollack"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10387&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Young Min_Chung","appointments":[{"appointment":"Postdoctoral Research fellow, Obstetrics & Gynecology"}],"clinicalFocus":[],"firstName":"Young Min","primaryAppointment":"Postdoctoral Research fellow, Obstetrics & Gynecology","displayName":"Young Min Chung","lastName":"Chung"},{"researchInterest":"Multi- modality treatment of Head and Neck Cancer\r\n\r\nPhase 1 clinical trials","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8044&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Alexander_Colevas","appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Medical Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"developmental therapeutics"},{"focus":"investigational new drugs"}],"firstName":"Alexander","primaryAppointment":"Associate Professor - Med Center Line,Medicine - Oncology","displayName":"Alexander Colevas","lastName":"Colevas"},{"researchInterest":"I specialize in the treatment of gastrointestinal malignancies.  I am interested in developing stereotactic body radiotherapy for tumors of the liver, both primary and metastatic.  I am interested in developing functional imaging as a means of determining treatment response with radiation.  I am also interested in developing image-guided radiotherapy to improve radiation delivery for GI cancers to reduce toxicity and improve disease outcome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8238&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Daniel_Chang","appointments":[{"appointment":"Assistant Professor - Med Center Line,Radiation Oncology - Radiation Therapy"}],"clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Cancer of the Stomach"},{"focus":"Cancer of Anus"},{"focus":"Cancer of Pancreas"},{"focus":"Cancer of the Rectum"},{"focus":"Cancer of the Liver"},{"focus":"Cancer of the Esophagus"},{"focus":"Cancer of the Head and Neck"}],"firstName":"Daniel","primaryAppointment":"Assistant Professor - Med Center Line,Radiation Oncology - Radiation Therapy","displayName":"Daniel Chang","lastName":"Chang"},{"researchInterest":"My research is in applied statistics and biostatistics. I specialize in \u000bcomputer-intensive methods for regression and classification, bootstrap, cross-validation\u000band statistical inference, and signal and image analysis for medical diagnosis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4688&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Tibshirani","appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Professor,Statistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Health Research & Policy - Biostatistics","displayName":"Robert Tibshirani","lastName":"Tibshirani"},{"researchInterest":"Clinical Interests: general oncology, head and neck cancer Research Interests: chemoprevention trials and combined modality approaches to head and neck cancer","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4027&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Harlan_Pinto","appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Esophageal Cancer"},{"focus":"Esophageal Cancer - Medical Oncology"},{"focus":"Head and Neck Cancers"},{"focus":"Head and Neck Cancers - Medical Oncology"},{"focus":"Internal Medicine"},{"focus":"Larynx Cancer "},{"focus":"Larynx Cancer - Medical Oncology"},{"focus":"Medical Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"Oral Cavity Cancer  "},{"focus":"Oral Cavity Cancer - Medical Oncology"},{"focus":"Salivary Gland Tumors"},{"focus":"Salivary Gland Tumors - Medical Oncology"},{"focus":"Skin Cancer "},{"focus":"Skin Cancer - Medical Oncology"},{"focus":"Skull Base Tumors "},{"focus":"Skull Base Tumors - Medical Oncology"},{"focus":"Thyroid Cancers"},{"focus":"Thyroid Cancers - Medical Oncology  "}],"firstName":"Harlan","primaryAppointment":"Associate Professor - Med Center Line,Medicine - Oncology","displayName":"Harlan Pinto","lastName":"Pinto"},{"researchInterest":"Hanawalt has been a productive researcher in the field of DNA repair since his pioneering discovery of repair replication in E. coli in 1963. He also first demonstrated repair replication in mycoplasmata and in a eukaryote and he has developed a number of important experimental approaches for studying repair, beginning with the BrdUrd density labeling method for resolving semiconservatively replicated DNA from parental DNA containing repair patches. Hanawalt\u0092s approach was used to validate the ","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Philip_Hanawalt","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Philip","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Philip Hanawalt","lastName":"Hanawalt"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9143&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Adam_Krieg","appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"clinicalFocus":[],"firstName":"Adam","primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","displayName":"Adam Krieg","lastName":"Krieg"},{"researchInterest":"Pediatric Hematology/Oncology, Phase I drug studies for refractory and relapsed leukemia; genomic studies, biologic risk-stratification and treatment of acute myeloid leukemia.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5921&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Norman_Lacayo","appointments":[{"appointment":"Assistant Professor - Med Center Line,Pediatrics - Hematology/Oncology"}],"clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Oncology (Cancer), Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"firstName":"Norman","primaryAppointment":"Assistant Professor - Med Center Line,Pediatrics - Hematology/Oncology","displayName":"Norman J. Lacayo, MD","lastName":"Lacayo"},{"researchInterest":"My lab focuses on cancer stem cell biology and its implications for cancer therapy. We are interested in developing a deeper molecular understanding of cancer stem cells, including identifying pathways and genes important for proliferation and self renewal. We also study these processes in normal adult stem cells in order to identify differences that could be exploited therapeutically. The goal of our studies is the development of novel therapeutic strategies for eliminating cancer stem cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9248&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Maximilian_Diehn","appointments":[{"appointment":"Acting Assistant Professor,Radiation Oncology - Radiation Therapy"}],"clinicalFocus":[],"firstName":"Maximilian","primaryAppointment":"Acting Assistant Professor,Radiation Oncology - Radiation Therapy","displayName":"Maximilian Diehn, M.D., Ph.D.","lastName":"Diehn"}]}