{"result":[{"researchInterest":"Our laboratory studies the basic molecular mechanisms of muscle stem cell activation, the effects of aging on skeletal muscle, and gene therapy for hereditary muscle diseases.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4063&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Rando","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"Thomas Rando","lastName":"Rando"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10169&type=small&showNoImage","href":"http://med.stanford.edu/profiles/George_Sen","appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"clinicalFocus":[],"firstName":"George","primaryAppointment":"Postdoctoral Research fellow, Dermatology","displayName":"George Sen","lastName":"Sen"},{"researchInterest":"My lab works on biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. We use a combination of gene profiling, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo.  For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For ESC, we are currently studying their tumorigenicity, immunogenicity, and differentiation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6159&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Joseph_Wu","appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Assistant Professor - Med Center Line,Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Congenital Heart Disease (Adult)"},{"focus":"Echocardiography"}],"firstName":"Joseph","primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","displayName":"Joseph  C. Wu","lastName":"Wu"},{"researchInterest":"We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in \"a vacuum\" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4036&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Christopher_Contag","appointments":[{"appointment":"Associate Professor,Pediatrics - Neonatology"},{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Associate Professor (By courtesy),Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Christopher","primaryAppointment":"Associate Professor,Pediatrics - Neonatology","displayName":"Christopher H. Contag","lastName":"Contag"},{"researchInterest":"Stem Cell Therapy for Myocardial Restoration, Cardiopulmonary Transplantation, Cardiac Allograft Vasculopathy, Automated Anastomotic Devices, Genetics and Mechanisms of Congestive Heart Failure","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4247&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Robbins","appointments":[{"appointment":"Professor,Cardiothoracic Surgery - Adult Cardiac Surgery"},{"appointment":"Professor (By courtesy),Surgery"}],"clinicalFocus":[{"focus":"Heart and Lung Transplantation"},{"focus":"Cardiothoracic Surgery"},{"focus":"Thoracic Surgery"}],"firstName":"Robert","primaryAppointment":"Professor,Cardiothoracic Surgery - Adult Cardiac Surgery","displayName":"Robert C. Robbins, M. D.","lastName":"Robbins"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"Our laboratory explores a variety of projects including angiogenesis, intestinal stem cell biology, and hepatic insulin resistance. Studies in angiogenesis include characterization of endothelial microRNA and GPCR ko mice, and anti-angiogenic therapy of cancer.  Our work on intestinal stem cell biology utilizes primary intestinal culture and in vivo adenoviral/ko strategies to study stem cells and model colon cancer.  Investigations into mechanisms of hepatic insulin resistance are underway.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Calvin_Kuo","appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Medical Oncology"}],"firstName":"Calvin","primaryAppointment":"Associate Professor,Medicine - Hematology","displayName":"Calvin Kuo","lastName":"Kuo"},{"researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Irving_Weissman","appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Irving","primaryAppointment":"Professor,Pathology - Stem Cell Institute","displayName":"Irving Weissman","lastName":"Weissman"},{"researchInterest":"We have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2)Distraction Osteogenesis, 3) Cleft Palate and Lip Biology, 4)Keloid and Hypertrophic Scar Biology, 5) Scarless Fetal Wound Healing, 6) Novel Gene and Stem Cell Therapeutic Approaches.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4338&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Longaker","appointments":[{"appointment":"Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Plastic Surgery"},{"focus":"Plastic Surgery, Pediatric"}],"firstName":"Michael","primaryAppointment":"Professor,Surgery - Plastic/Recon Surgery","displayName":"Michael Longaker","lastName":"Longaker"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9179&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ngan_Huang","appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"clinicalFocus":[],"firstName":"Ngan","primaryAppointment":"Postdoctoral Research fellow, Medicine","displayName":"Ngan Huang","lastName":"Huang"},{"researchInterest":"We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4683&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Paul_Khavari","appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Paul","primaryAppointment":"Professor,Dermatology","displayName":"Paul A. Khavari, MD, PhD","lastName":"Khavari"},{"researchInterest":"My research interests are vascular biology and cardiovascular pathology.  We are currently working on gene expression in endothelial cells at sites of pathology.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6324&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Andrew_Connolly","appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"clinicalFocus":[{"focus":"Anatomic Pathology"}],"firstName":"Andrew","primaryAppointment":"Associate Professor - Med Center Line,Pathology","displayName":"Andrew J. Connolly","lastName":"Connolly"},{"researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Gerald","primaryAppointment":"Professor,Pathology","displayName":"Gerald Crabtree","lastName":"Crabtree"},{"researchInterest":"Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Geoffrey_Gurtner","appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Plastic Surgery"}],"firstName":"Geoffrey","primaryAppointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery","displayName":"Geoffrey Gurtner","lastName":"Gurtner"},{"researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Clarke","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Michael","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Michael F. Clarke, M.D.","lastName":"Clarke"},{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed.  Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology,  as well as in molecular therapeutics including gene therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3971&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Sanjiv_Gambhir","appointments":[{"appointment":"Professor,Radiology - Nuclear Medicine"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Nuclear Medicine"},{"focus":"Radiology"},{"focus":"PET Scan"}],"firstName":"Sanjiv","primaryAppointment":"Professor,Radiology - Nuclear Medicine","displayName":"Sanjiv Sam Gambhir, MD, PhD","lastName":"Gambhir"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14774&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ramasamy_Paulmurugan","appointments":[{"appointment":"Acting Assistant Professor,Radiology"}],"clinicalFocus":[],"firstName":"Ramasamy","primaryAppointment":"Acting Assistant Professor,Radiology","displayName":"Ramasamy Paulmurugan","lastName":"Paulmurugan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8938&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mei_Huang","appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"clinicalFocus":[],"firstName":"Mei","primaryAppointment":"Postdoctoral Research fellow, Radiology","displayName":"Mei Huang","lastName":"Huang"},{"researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have idintified a gene (GRAIL) that seems to control T cell anergy and are defining the regulatory T cell core transcriptome.  Additional studies are on the mechanism of effect of anti-CD3 antibodies in therapy of T1D.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","href":"http://med.stanford.edu/profiles/C_Fathman","appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"firstName":"C","primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","displayName":"C. Garrison Fathman","lastName":"Fathman"},{"researchInterest":"Epigenetic Reprogramming, Pluripotent Stem Cells, Neural Differentiation: implications in development and regenerative medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10445&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Marius_Wernig","appointments":[{"appointment":"Assistant Professor,Pathology - Stem Cell Institute"}],"clinicalFocus":[],"firstName":"Marius","primaryAppointment":"Assistant Professor,Pathology - Stem Cell Institute","displayName":"Marius Wernig","lastName":"Wernig"},{"researchInterest":"Embryonic stem cell differentiation, angiogenesis","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8756&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zongjin_Li","appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"clinicalFocus":[],"firstName":"Zongjin","primaryAppointment":"Postdoctoral Research fellow, Radiology","displayName":"Zongjin Li","lastName":"Li"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"}]}