{"result":[{"researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Daniel_Arber","appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Daniel","primaryAppointment":"Professor - Med Center Line,Pathology","displayName":"Daniel A. Arber, M.D.","lastName":"Arber"},{"researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Irving_Weissman","appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Irving","primaryAppointment":"Professor,Pathology - Stem Cell Institute","displayName":"Irving Weissman","lastName":"Weissman"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"Hematology/Oncology, treatment of sarcomas of bone and soft tissue, biology of acute lymphoblastic leukemias, treatment of non-Hodgkin's lymphoma and Hodgkin's disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4631&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Link","appointments":[{"appointment":"Professor,Pediatrics - Hematology/Oncology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"firstName":"Michael","primaryAppointment":"Professor,Pediatrics - Hematology/Oncology","displayName":"Michael Link","lastName":"Link"},{"researchInterest":"The research in my laboratory involves the application of monoclonal and polyclonal antibodies and a variety of immunohistochemical methods to study human B-cell, T-cell, accessory cell and related neoplasms.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3786&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Roger_Warnke","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Roger","primaryAppointment":"Professor,Pathology","displayName":"Roger Warnke","lastName":"Warnke"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8999&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zhong_Wang","appointments":[{"appointment":"Instructor,Pathology"}],"clinicalFocus":[],"firstName":"Zhong","primaryAppointment":"Instructor,Pathology","displayName":"Zhong Wang","lastName":"Wang"},{"researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Linda_Boxer","appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"firstName":"Linda","primaryAppointment":"Professor,Medicine - Hematology","displayName":"Linda Boxer","lastName":"Boxer"},{"researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Clarke","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Michael","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Michael F. Clarke, M.D.","lastName":"Clarke"},{"researchInterest":"Bone marrow transplantation (BMT) is a treatment modality which is being broadly applied to a growing number of disorders. Increasing success with BMT is offering improved survival to pediatric and adult patients with acute leukemia, chronic leukemia, lymphomas, and a variety of solid tumors as well as severe aplastic anemia.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6097&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Amylon","appointments":[{"appointment":"Emeritus (Active) Professor,Pediatrics - Stem Cell Transplantation"}],"clinicalFocus":[{"focus":"Pediatric Hematology-Oncology"},{"focus":"Ped Hematology/Oncology"}],"firstName":"Michael","primaryAppointment":"Emeritus (Active) Professor,Pediatrics - Stem Cell Transplantation","displayName":"Michael Amylon","lastName":"Amylon"},{"researchInterest":"My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues.  We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues.  The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the devel","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ching-Pin_Chang","appointments":[{"appointment":"Assistant Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ching-Pin","primaryAppointment":"Assistant Professor,Medicine - Cardiovascular Medicine","displayName":"Ching-Pin Chang","lastName":"Chang"},{"researchInterest":"Research in our lab focuses on mechanisms of epigenetic regulation in differentiation and development. In particular, we are studying the function of histone modifying enzymes in embryonic stem cell self-renewal and in early cell fate decisions. We are interested in the role of chromatin modifications in establishment and maintenance of gene expression patterns during normal and pathological development, and in nuclear reprogramming.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7764&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Joanna_Wysocka","appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Assistant Professor,Developmental Biology"}],"clinicalFocus":[],"firstName":"Joanna","primaryAppointment":"Assistant Professor,Chemical and Systems Biology","displayName":"Joanna Wysocka","lastName":"Wysocka"},{"researchInterest":"My research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5929&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Yasodha_Natkunam","appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematopathology"},{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"Yasodha","primaryAppointment":"Associate Professor - Med Center Line,Pathology","displayName":"Yasodha Natkunam, M.D., Ph.D","lastName":"Natkunam"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"Clinical Interests: lymphoma. Research Interests: Immunology and molecular biology of lymphoid malignancy; molecular vaccines for cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4608&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ronald_Levy","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Lymphoma "},{"focus":"Non-Hodgkin's Lymphoma"},{"focus":"Non-Hodgkin's Lymphoma - Medical Oncology"},{"focus":"Burkitt's Lymphoma"},{"focus":"Burkitt's Lymphoma - Medical Oncology"},{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Burkitt's Lymphoma - Hematology"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"Non-Hodgkin's Lymphoma - Hematology"}],"firstName":"Ronald","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Ronald Levy, MD","lastName":"Levy"},{"researchInterest":"Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4008&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Matt_Van de Rijn","appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"Matt","primaryAppointment":"Professor - Med Center Line,Pathology","displayName":"Matt Van de Rijn","lastName":"Van de Rijn"},{"researchInterest":"My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5931&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Dean_Felsher","appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Lymphoma "},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Dean","primaryAppointment":"Associate Professor,Medicine - Oncology","displayName":"Dean W. Felsher","lastName":"Felsher"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4138&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Negrin","appointments":[{"appointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"firstName":"Robert","primaryAppointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation","displayName":"Robert Negrin","lastName":"Negrin"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9759&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kryn_Stankunas","appointments":[{"appointment":"Instructor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Kryn","primaryAppointment":"Instructor,Medicine - Cardiovascular Medicine","displayName":"Kryn Stankunas","lastName":"Stankunas"},{"researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Leonore","primaryAppointment":"Professor (Research),Genetics","displayName":"Leonore A. Herzenberg","lastName":"Herzenberg"},{"researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Gerald","primaryAppointment":"Professor,Pathology","displayName":"Gerald Crabtree","lastName":"Crabtree"},{"researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Uta_Francke","appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"firstName":"Uta","primaryAppointment":"Professor,Genetics","displayName":"Uta Francke","lastName":"Francke"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"},{"researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jane_Parnes","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jane","primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","displayName":"Jane Parnes","lastName":"Parnes"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"}]}