{"result":[{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6212&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Allan_Campbell","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Allan","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Allan Campbell","lastName":"Campbell"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Uta_Francke","appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"firstName":"Uta","primaryAppointment":"Professor,Genetics","displayName":"Uta Francke","lastName":"Francke"},{"researchInterest":"My lab is developing novel vectors and strategies for gene therapy.  We are focused on creating and using plasmid DNA vectors that integrate into the genome in a site-specific manner.  We are developing innovative gene therapies for a variety of tissues and diseases, including approaches involving stem cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4100&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michele_Calos","appointments":[{"appointment":"Professor,Genetics"}],"clinicalFocus":[],"firstName":"Michele","primaryAppointment":"Professor,Genetics","displayName":"Michele Calos","lastName":"Calos"},{"researchInterest":"For about 10 years until 2000, my lab\u0092s research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Paul_Berg","appointments":[{"appointment":"Emeritus (Active) Professor,Biochemistry"},{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"clinicalFocus":[],"firstName":"Paul","primaryAppointment":"Emeritus (Active) Professor,Biochemistry","displayName":"Paul Berg","lastName":"Berg"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9655&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kwang-sun_Kim","appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"clinicalFocus":[],"firstName":"Kwang-sun","primaryAppointment":"Postdoctoral Research fellow, Genetics","displayName":"Kwang-sun Kim","lastName":"Kim"},{"researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4488&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stanley_Falkow","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Professor,Medicine"}],"clinicalFocus":[],"firstName":"Stanley","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Stanley Falkow","lastName":"Falkow"},{"researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ronald_Davis","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Ronald","primaryAppointment":"Professor,Biochemistry","displayName":"Ronald Davis","lastName":"Davis"},{"researchInterest":"The photochemistry and radiation chemistry of DNA, the genetic control and biochemical bases of the multiple pathways of DNA repair, and the roles of DNA repair processes in radiation and spontaneous mutagenesis. Over 190 papers have been published on these and related topics.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7014&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kendric_Smith","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology"}],"clinicalFocus":[],"firstName":"Kendric","primaryAppointment":"Emeritus Faculty, Acad Council,Radiation Oncology","displayName":"Kendric C. Smith","lastName":"Smith"},{"researchInterest":"The Puglisi group investigates the role of RNA in cellular processes and disease.  We investigate dynamics using single-molecule approaches.  Our goal is a unified picture of structure, dynamics and function.  We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections.  A long-term goal is to target processes involving RNA with novel therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4431&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Joseph_Puglisi","appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Joseph","primaryAppointment":"Professor,Structural Biology","displayName":"Joseph (Jody) Puglisi","lastName":"Puglisi"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Charles_Yanofsky","appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Charles","primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","displayName":"Charles Yanofsky","lastName":"Yanofsky"},{"researchInterest":"Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4458&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Peter_Sarnow","appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Peter","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Peter Sarnow","lastName":"Sarnow"},{"researchInterest":"Alternative modes of Wnt-signal transduction","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9613&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Renee_van Amerongen","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Renee","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Renee van Amerongen","lastName":"van Amerongen"},{"researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_McKay","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","displayName":"David B. McKay","lastName":"McKay"},{"researchInterest":"1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity; 4. Bioremediation.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4329&type=small&showNoImage","href":"http://med.stanford.edu/profiles/AC_Matin","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"AC","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"AC Matin","lastName":"Matin"},{"researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Clarke","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Michael","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Michael F. Clarke, M.D.","lastName":"Clarke"},{"researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Albert_Wong","appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Albert","primaryAppointment":"Professor,Neurosurgery","displayName":"Albert J. Wong, M.D.","lastName":"Wong"},{"researchInterest":"My laboratory focuses on understanding the transcriptional processes that govern the transformation of normal mammalian cells to neoplastic state.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zijie_Sun","appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Zijie","primaryAppointment":"Associate Professor,Urology","displayName":"Zijie Sun","lastName":"Sun"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jonathan_Pollack","appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jonathan","primaryAppointment":"Associate Professor,Pathology","displayName":"Jonathan Pollack","lastName":"Pollack"},{"researchInterest":"The aim of my research is to investigate the mechanisms, frequency, and consequences of the evolutionary shifts experienced by bacteria. Some more specific areas of research include:\r\n\r\n(1)  Quantifying shifts in the strength of purifying selection and understanding the consequences of such shifts\r\n \r\n(2)  Determining whether shifts in nucleotide content are driven by shifts in mutation or shifts in selection\r\n\r\n(3)  Establishing the mechanisms of shifts in codon usage bias","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10299&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ruth_Hershberg","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Ruth","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"Ruth Hershberg","lastName":"Hershberg"},{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"I refer you to my web page for detailed list of interests, projects and publications.  In addition to pressing the link here, you can search \"Russ Altman\" on http://www.google.com/","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4706&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Russ_Altman","appointments":[{"appointment":"Professor,Bioengineering"},{"appointment":"Professor,Medicine - BMIR"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Russ","primaryAppointment":"Professor,Bioengineering","displayName":"Russ B. Altman","lastName":"Altman"}]}