{"result":[{"researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Richard_Tsien","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Richard","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Richard Tsien","lastName":"Tsien"},{"researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Malenka","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Robert Malenka","lastName":"Malenka"},{"researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4531&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_Prince","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"David Prince","lastName":"Prince"},{"researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Sudhof","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Thomas Sudhof","lastName":"Sudhof"},{"researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4009&type=small&showNoImage","href":"http://med.stanford.edu/profiles/M_MacIver","appointments":[{"appointment":"Associate Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"M","primaryAppointment":"Associate Professor (Research),Anesthesia","displayName":"M Bruce MacIver","lastName":"MacIver"},{"researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","href":"http://med.stanford.edu/profiles/John_Huguenard","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"John","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"John Huguenard","lastName":"Huguenard"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6245&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stuart_Thompson","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Stuart","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Stuart Thompson","lastName":"Thompson"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zhiping_Pang","appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"clinicalFocus":[],"firstName":"Zhiping","primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","displayName":"Zhiping Pang","lastName":"Pang"},{"researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Craig_Garner","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Craig","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Craig C. Garner","lastName":"Garner"},{"researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Shaul_Hestrin","appointments":[{"appointment":"Associate Professor,Comparative Medicine"}],"clinicalFocus":[],"firstName":"Shaul","primaryAppointment":"Associate Professor,Comparative Medicine","displayName":"Shaul Hestrin","lastName":"Hestrin"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9967&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stephen_Towers","appointments":[],"clinicalFocus":[],"firstName":"Stephen","displayName":"Stephen Towers","lastName":"Towers"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8925&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Carson_Goddard","appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"clinicalFocus":[],"firstName":"Carson","primaryAppointment":"Postdoctoral Research fellow, Neurobiology","displayName":"Carson Goddard","lastName":"Goddard"},{"researchInterest":"Research in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6080&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Karl_Deisseroth","appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Psychiatry"}],"firstName":"Karl","primaryAppointment":"Assistant Professor,Bioengineering","displayName":"Karl Deisseroth","lastName":"Deisseroth"},{"researchInterest":"The Penn lab is studying the role of placental factors in brain development.  We are using novel mouse models to explore factors that contribute to normal neurodevelopment and the effects of their loss following premature birth.  We are focused on the influence of steroid hormones (estrogens and progestins) on cerebellar development and, collaboratively, are extending our studies to hippocampal stem cells and forebrain neurons.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4030&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anna_Penn","appointments":[{"appointment":"Assistant Professor,Pediatrics - Neonatology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"}],"firstName":"Anna","primaryAppointment":"Assistant Professor,Pediatrics - Neonatology","displayName":"Anna Penn","lastName":"Penn"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10593&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Laura_Elias","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Laura","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Laura AB Elias","lastName":"Elias"},{"researchInterest":"The goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8146&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Carla_Shatz","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Carla","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Carla Shatz","lastName":"Shatz"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15397&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jieun_Shin","appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"clinicalFocus":[],"firstName":"Jieun","primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","displayName":"Jieun Shin","lastName":"Shin"},{"researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ben_Barres","appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"clinicalFocus":[],"firstName":"Ben","primaryAppointment":"Professor,Neurobiology","displayName":"Ben Barres","lastName":"Barres"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9883&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Chris_Dulla","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Chris","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Chris Dulla","lastName":"Dulla"},{"researchInterest":"Mechanisms of epilepsy, especially temporal lobe epilepsy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4415&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Paul_Buckmaster","appointments":[{"appointment":"Associate Professor,Comparative Medicine"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Paul","primaryAppointment":"Associate Professor,Comparative Medicine","displayName":"Paul Buckmaster, DVM, PhD","lastName":"Buckmaster"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9912&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Samarjit_Bhattacharyya","appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"clinicalFocus":[],"firstName":"Samarjit","primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","displayName":"Samarjit Bhattacharyya","lastName":"Bhattacharyya"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6061&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kevin_Graber","appointments":[{"appointment":"Clinical Assistant Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Kevin","primaryAppointment":"Clinical Assistant Professor,Neurology & Neurological Sciences","displayName":"Kevin Graber, M.D.","lastName":"Graber"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ofer_Yizhar","appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"clinicalFocus":[],"firstName":"Ofer","primaryAppointment":"Postdoctoral Research fellow, Bioengineering","displayName":"Ofer Yizhar","lastName":"Yizhar"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7204&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kwabena_Boahen","appointments":[{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor (By courtesy),Electrical Engineering"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Kwabena","primaryAppointment":"Associate Professor,Bioengineering","displayName":"Kwabena Boahen","lastName":"Boahen"},{"researchInterest":"Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders.  We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4040&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ricardo_Dolmetsch","appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ricardo","primaryAppointment":"Assistant Professor,Neurobiology","displayName":"Ricardo Dolmetsch","lastName":"Dolmetsch"}]}