{"result":[{"researchInterest":"My research focuses on the molecular and cellular biology of the human prostate. Developing realistic experimental models is a major goal, and primary cultures of prostatic epithelial and stromal cells are my main model system. Our discoveries are relevant to prevention, detection, diagnosis and treatment of benign and malignant prostatic diseases.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4633&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Donna_Peehl","appointments":[{"appointment":"Professor (Research),Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Donna","primaryAppointment":"Professor (Research),Urology","displayName":"Donna Peehl","lastName":"Peehl"},{"researchInterest":"We have used comprehensive gene expression profiling for 2 translational research objectives: 1) to understand the mechanisms of action of candidate prostate cancer preventive agents and develop biomarkers that we can use to evaluate response; and 2) to identify diagnostic and prognostic markers for prostate, kidney, testicular and bladder cancers.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6178&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Brooks","appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Male Cancers - Prostate "},{"focus":"Prostate Cancer"},{"focus":"Nerve-sparing radical prostatectomy"},{"focus":"Prostate Cancer - Urologic Oncology"},{"focus":"Urologic Cancers"},{"focus":"Urologic Cancers - Urologic Oncology"},{"focus":"Urology"}],"firstName":"James","primaryAppointment":"Associate Professor,Urology","displayName":"James D. Brooks","lastName":"Brooks"},{"researchInterest":"My laboratory focuses on understanding the transcriptional processes that govern the transformation of normal mammalian cells to neoplastic state.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zijie_Sun","appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Zijie","primaryAppointment":"Associate Professor,Urology","displayName":"Zijie Sun","lastName":"Sun"},{"researchInterest":"chemoprevetion, HDAC inhibitors, miRNAs, tumor suppressor genes","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10537&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Emily_Noonan","appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"clinicalFocus":[],"firstName":"Emily","primaryAppointment":"Postdoctoral Research fellow, Medicine","displayName":"Emily Noonan Ph.D.","lastName":"Noonan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8514&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Rajnish_Gupta","appointments":[{"appointment":"Instructor,Dermatology"},{"appointment":"Postdoctoral Medical fellow, Dermatology"}],"clinicalFocus":[{"focus":"Dermatology"},{"focus":"Psoriasis"},{"focus":"Dermatitis, Atopic"},{"focus":"Scleroderma, Localized"},{"focus":"Lupus Erythematosus, Cutaneous"},{"focus":"Lupus Erythematosus, Discoid"},{"focus":"Dermatomyositis"}],"firstName":"Rajnish","primaryAppointment":"Instructor,Dermatology","displayName":"Rajnish Gupta","lastName":"Gupta"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ronald_Davis","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Ronald","primaryAppointment":"Professor,Biochemistry","displayName":"Ronald Davis","lastName":"Davis"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4031&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jeffrey_Faig","appointments":[{"appointment":"Clinical Associate Professor,Obstetrics & Gynecology"}],"clinicalFocus":[{"focus":"Obstetrics and Gynecology"},{"focus":"Diabetes in Pregnancy"},{"focus":"Thyroid Disease in Pregnancy"},{"focus":"Endocrinopathies in Pregnancy"},{"focus":"Obstetrics"},{"focus":"Endocrinology"}],"firstName":"Jeffrey","primaryAppointment":"Clinical Associate Professor,Obstetrics & Gynecology","displayName":"Jeffrey Clayton Faig, MD, FACOG","lastName":"Faig"},{"researchInterest":"Etiology of breast, prostate and ovarian cancer; cancer in Hispanics and African-Americans; migration and acculturation in Hispanics; modifiable lifestyle factors (vitamin D, physical activity, body size, heterocyclic amines, occupational exposures); genetic susceptibility; gene-environment interactions","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7425&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Esther_John","appointments":[{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Esther","primaryAppointment":"Member,Cancer Center","displayName":"Esther M. John","lastName":"John"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"- Cancer etiology (diet, familial, genetic), especially breast, prostate and colon cancer\r\n- Cancer surveillance (Cancer registration, cancer patterns)\r\n- Cancer outcomes (Survival, quality of life, quality of care)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6327&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Dee_West","appointments":[{"appointment":"Professor,Health Research & Policy - Epidemiology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Dee","primaryAppointment":"Professor,Health Research & Policy - Epidemiology","displayName":"Dee W. West","lastName":"West"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"Cancers of the prostate, breast and ovary account for a major proportion of new cancer cases and cancer deaths in the U.S. each year. Our recent research focus has been on developing improved statistical methods for the design and conduct of studies involving hereditary predisposition and modifiable lifestyle characteristics in the etiologies of site-specific cancers.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4482&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Alice_Whittemore","appointments":[{"appointment":"Professor,Health Research & Policy - Epidemiology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Alice","primaryAppointment":"Professor,Health Research & Policy - Epidemiology","displayName":"Alice S Whittemore","lastName":"Whittemore"},{"researchInterest":"refine detection strategies for prostate cancer, identify prognostic indicators for prostate cancer patients","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4717&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Joseph_Presti","appointments":[{"appointment":"Professor - Med Center Line,Urology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"prostate cancer"},{"focus":"bladder cancer"},{"focus":"kidney cancer"},{"focus":"Nerve Sparing Radical Prostatectomy"},{"focus":"testicular cancer"},{"focus":"radical cystectomy"},{"focus":"partial nephrectomy"},{"focus":"radical nephrectomy"},{"focus":"Urologic Oncology"},{"focus":"Urology"}],"firstName":"Joseph","primaryAppointment":"Professor - Med Center Line,Urology","displayName":"Joseph Presti, Jr.","lastName":"Presti"},{"researchInterest":"My laboratory is focused on studying the role of DNA methylation in prostate and bladder cancer.  Certain genes and their downstream targets may be useful molecular markers for disease detection and prognostication. We are interested in utilizing methylation markers to detect abnormal changes in serum and urine.  Clinical Focus: Prostate Cancer - Robotic Prostatectomy; Bladder Cancer - Robotic Cystectomy; Urologic Oncology - Prostate, Bladder, Kidney, Testicular Cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13213&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Gonzalgo","appointments":[{"appointment":"Associate Professor - Med Center Line,Urology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Prostate Cancer - Robotic Prostatectomy"},{"focus":"Bladder Cancer - Robotic Cystectomy"},{"focus":"Urologic Oncology - Prostate, Bladder, Kidney, Testicular Cancer"},{"focus":"Urology"}],"firstName":"Mark","primaryAppointment":"Associate Professor - Med Center Line,Urology","displayName":"Mark L. Gonzalgo, M.D., Ph.D.","lastName":"Gonzalgo"},{"researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jonathan_Pollack","appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jonathan","primaryAppointment":"Associate Professor,Pathology","displayName":"Jonathan Pollack","lastName":"Pollack"},{"researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Linda_Boxer","appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"firstName":"Linda","primaryAppointment":"Professor,Medicine - Hematology","displayName":"Linda Boxer","lastName":"Boxer"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11414&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Megan_Albertelli","appointments":[{"appointment":"Assistant Professor - Med Center Line,Comparative Medicine"}],"clinicalFocus":[],"firstName":"Megan","primaryAppointment":"Assistant Professor - Med Center Line,Comparative Medicine","displayName":"Megan Albertelli","lastName":"Albertelli"},{"researchInterest":"Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6012&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anne_Brunet","appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Anne","primaryAppointment":"Assistant Professor,Genetics","displayName":"Anne Brunet","lastName":"Brunet"},{"researchInterest":"Our interests in clude 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, and 3) the role of radiation in tumor vaccine strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4699&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_Knox","appointments":[{"appointment":"Associate Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Radiation Therapy"}],"firstName":"Susan","primaryAppointment":"Associate Professor,Radiation Oncology - Radiation Therapy","displayName":"Susan Knox","lastName":"Knox"},{"researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Glenn_Rosen","appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonology (Lung) and Critical Care "}],"firstName":"Glenn","primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med","displayName":"Glenn Rosen","lastName":"Rosen"},{"researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Frank_Longo","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"firstName":"Frank","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"Frank M. Longo, M.D., Ph.D.","lastName":"Longo"},{"researchInterest":"Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA\u000bdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Ford","appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Associate Professor (By courtesy),Pediatrics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Cancer Genetics"},{"focus":"Gastrointestinal Cancers - Genetics"},{"focus":"Gastrointestinal Cancers - Medical Oncology"},{"focus":"Breast Cancer - Genetics"},{"focus":"Ovarian Cancer - Genetics"},{"focus":"Medical Oncology"}],"firstName":"James","primaryAppointment":"Associate Professor,Medicine - Oncology","displayName":"James Ford","lastName":"Ford"}]}