{"result":[{"lastName":"Sherlock","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5864&type=small&showNoImage","displayName":"Gavin Sherlock","firstName":"Gavin","href":"http://med.stanford.edu/profiles/Gavin_Sherlock","researchInterest":"Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species; genome database for Candida albicans; genome database for Aspergilli; the Stanford Microarray Database; The Tuberculosis Database; bioinformatics tools for analysing expression data."},{"lastName":"Altman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Bioengineering"},{"appointment":"Professor,Medicine - BMIR"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4706&type=small&showNoImage","displayName":"Russ B. Altman","firstName":"Russ","href":"http://med.stanford.edu/profiles/Russ_Altman","researchInterest":"I refer you to my web page for detailed list of interests, projects and publications.  In addition to pressing the link here, you can search \"Russ Altman\" on http://www.google.com/"},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","displayName":"Ronald Davis","firstName":"Ronald","href":"http://med.stanford.edu/profiles/Ronald_Davis","researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Fraser","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15112&type=small&showNoImage","displayName":"Hunter Fraser","firstName":"Hunter","href":"http://med.stanford.edu/profiles/Hunter_Fraser","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Statistics"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6454&type=small&showNoImage","displayName":"Wing Wong","firstName":"Wing","href":"http://med.stanford.edu/profiles/Wing_Wong","researchInterest":"Current interest centers on the application of statistics to problems arsing from biology. We are particularly interested in questions concerning gene regulation and signal transduction."},{"lastName":"Petrov","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6234&type=small&showNoImage","displayName":"Dmitri Petrov","firstName":"Dmitri","href":"http://med.stanford.edu/profiles/Dmitri_Petrov","researchInterest":""},{"lastName":"Butte","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Cancer Biology"},{"appointment":"Assistant Professor,Medicine"},{"appointment":"Assistant Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Pediatrics - Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6603&type=small&showNoImage","displayName":"Atul Butte","firstName":"Atul","href":"http://med.stanford.edu/profiles/Atul_Butte","researchInterest":"Translational bioinformatics has been defined as the development of analytic\r\nmethods to help transform increasingly voluminous genomic and biological data into diagnostics and therapeutics for the clinician.  The long-term research goal of the Butte Lab is to develop translational bioinformatics methods to reason over many available genome-scale measurement and experimental modalities, and apply these methods to study complex disorders in genomic medicine, especially obesity and diabetes."},{"lastName":"Jonquet","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biomedical Informatics (IDP)"}],"primaryAppointment":"Postdoctoral Research fellow, Biomedical Informatics (IDP)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8970&type=small&showNoImage","displayName":"Clement Jonquet","firstName":"Clement","href":"http://med.stanford.edu/profiles/Clement_Jonquet","researchInterest":""},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9664&type=small&showNoImage","displayName":"Chih Long Liu","firstName":"Chih","href":"http://med.stanford.edu/profiles/Chih_Liu","researchInterest":""},{"lastName":"Ptacek","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9103&type=small&showNoImage","displayName":"Jason Ptacek","firstName":"Jason","href":"http://med.stanford.edu/profiles/Jason_Ptacek","researchInterest":""},{"lastName":"Frommer","clinicalFocus":[],"appointments":[{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6305&type=small&showNoImage","displayName":"Wolf B. Frommer","firstName":"Wolf","href":"http://med.stanford.edu/profiles/Wolf_Frommer","researchInterest":"Watching cells at work \r\nFocus: Transport / signaling across the plasma membrane (sugars, amino acids). \r\nTools: FRET-based nanosensors for metabolite imaging (with subcellular resolution) in living organisms using confocal fluorescence microscopy and HTS; Sensor optimization by computational design; RNAi to modify cellular functions.\r\nGoals: Identify unknown sugar effluxers from liver/plant cells; study regulatory networks. \r\nModel systems: liver, neuronal, plant cell cultures, Arabidopsis, yeast"},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/Arend_Sidow","researchInterest":"We study the function and molecular evolution of proteins and noncoding functional elements in the genome.  Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Musen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - BMIR"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - BMIR","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4164&type=small&showNoImage","displayName":"Mark Musen","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Musen","researchInterest":"My laboratory investigates the use of distributed, component-based software architectures to build intelligent computer systems. Emphasis is on knowledge modeling and knowledge reuse. Our goals are to enhance methodologies that faculitate building and maintaining electronic knowledge bases that can drive useful biomedical computer systems. Current work concentrates on automation of clinical practice guidelines and clinical-trial protocols, and surveillance for potential episodes of bioterrorism."},{"lastName":"Collins","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10605&type=small&showNoImage","displayName":"Sean Collins","firstName":"Sean","href":"http://med.stanford.edu/profiles/Sean_Collins","researchInterest":""},{"lastName":"Rubin","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10416&type=small&showNoImage","displayName":"Daniel Rubin","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Rubin","researchInterest":"My research interest is imaging informatics--ways computers can work with images to leverage their rich information content and to help physicians use images to guide personalized care. Work in our lab thus lies at the intersection of biomedical informatics and imaging science."},{"lastName":"Kornberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4308&type=small&showNoImage","displayName":"Roger Kornberg","firstName":"Roger","href":"http://med.stanford.edu/profiles/Roger_Kornberg","researchInterest":"We study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells"},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Biochemistry"},{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus (Active) Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab\u0092s research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Barton","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Associate Professor (By courtesy),Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6253&type=small&showNoImage","displayName":"Kathryn Barton","firstName":"Kathryn","href":"http://med.stanford.edu/profiles/Kathryn_Barton","researchInterest":""},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Elias","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12511&type=small&showNoImage","displayName":"Joshua Elias","firstName":"Joshua","href":"http://med.stanford.edu/profiles/Joshua_Elias","researchInterest":"Developing new mass spectrometry-based experimental and computational tools that advance the field of proteomics, and applying them to a variety of important biomedical paradigms, including cancer, aging, and stem cell biology."},{"lastName":"Tran","clinicalFocus":[],"appointments":[{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Member,Cancer Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8562&type=small&showNoImage","displayName":"Phuoc T. Tran","firstName":"Phuoc","href":"http://med.stanford.edu/profiles/Phuoc_Tran","researchInterest":""},{"lastName":"Klein","clinicalFocus":[],"appointments":[{"appointment":"Sr Research Engineer (PI Waiver),Genetics"}],"primaryAppointment":"Sr Research Engineer (PI Waiver),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6129&type=small&showNoImage","displayName":"Teri Klein","firstName":"Teri","href":"http://med.stanford.edu/profiles/Teri_Klein","researchInterest":"Co-founder, Pacific Symposium on Biocomputing\r\nNIEHS, Site Visit Reviewer\r\nNIH, Study Section Reviewer"},{"lastName":"Flaherty","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10273&type=small&showNoImage","displayName":"Patrick Flaherty","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Flaherty","researchInterest":""}]}