{"result":[{"lastName":"Dekker","clinicalFocus":[{"focus":"Pediatric Infectious Disease"},{"focus":"Vaccine Clinical Trials"},{"focus":"Vaccine Safety"},{"focus":"Infectious Diseases, Pediatric"}],"appointments":[{"appointment":"Professor (Research),Pediatrics - Infectious Diseases"}],"primaryAppointment":"Professor (Research),Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3858&type=small&showNoImage","displayName":"Cornelia L. Dekker, M.D.","firstName":"Cornelia","href":"http://med.stanford.edu/profiles/Cornelia_Dekker","researchInterest":"The Stanford-LPCH Program provides an infrastructure for conducting clinical studies of new vaccines in children and adults. Current emphasis is on seasonal and avian influenza, malaria and smallpox vaccine studies. We secreend 20,000 newborn infants for congenital HCMV infection in 3 local hospitals and continue with prospective audiology and immunology follow-up of identified children. Additionally, we are a CDC Clinical Immunization Safety Assessment site to evaluate licensed vaccine safety."},{"lastName":"Gans","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pediatrics - Infectious Diseases"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4053&type=small&showNoImage","displayName":"Hayley Gans","firstName":"Hayley","href":"http://med.stanford.edu/profiles/Hayley_Gans","researchInterest":"The focus of my laboratory is the immune response to viral vaccines evaluating the ontogeny of responses in infants and limitations in immunocompromised hosts.  We have studied responses to an early two-dose measles immunization, one versus 2 doses of varicella immunization, and polio vaccine in preterm versus term infants. Other active areas of research include measles and varicella immunity in HIV infected individuals, and transplant recipients."},{"lastName":"Prober","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4095&type=small&showNoImage","displayName":"Charles G. Prober","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Prober","researchInterest":"My area of research interest is focused on the epidemiology, pathophysiology, prevention, and treatment of infections in children. Much of my research has focused on viral infections, especially those caused by herpes simplex virus (HSV). I have conducted a number of studies concerned with the epidemiology of HSV-2 infections in pregnant women, their partners, and neonates. Recently, I have extended these epidemiologic studies to adolescents."},{"lastName":"Maldonado","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor (By courtesy),Health Research & Policy"}],"primaryAppointment":"Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4663&type=small&showNoImage","displayName":"Yvonne Maldonado","firstName":"Yvonne","href":"http://med.stanford.edu/profiles/Yvonne_Maldonado","researchInterest":"My research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio.  I also work in development of methods to prevent breastfeeding transmission of HIV in Africa."},{"lastName":"Lewis","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4439&type=small&showNoImage","displayName":"David B. Lewis","firstName":"David","href":"http://med.stanford.edu/profiles/David_Lewis","researchInterest":"My laboratory has two major research interests.  First, to define cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies.  Second, to determine how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants, with a particular focus on anti-viral vaccines."},{"lastName":"Reichelt","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9514&type=small&showNoImage","displayName":"Mike Reichelt","firstName":"Mike","href":"http://med.stanford.edu/profiles/Mike_Reichelt","researchInterest":""},{"lastName":"Engleman","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","displayName":"Edgar Engleman","firstName":"Edgar","href":"http://med.stanford.edu/profiles/Edgar_Engleman","researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease."},{"lastName":"Mocarski","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4146&type=small&showNoImage","displayName":"Edward Mocarski","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Mocarski","researchInterest":"Research focusses on one of the human herpesviruses: cytomegalovirus (CMV). This virus is a major medical problem in immunocompromised individuals. The virus is very large, carrying over 200 genes. We have characterized functions involved in viral growth (regulation of gene expression, replication, genome packaging) and pathogenesis (tissue tropism, latency). Molecular genetic and biochemical approaches have been employed to dissect these functions."},{"lastName":"Greenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3791&type=small&showNoImage","displayName":"Harry B Greenberg","firstName":"Harry","href":"http://med.stanford.edu/profiles/Harry_Greenberg","researchInterest":"Molecular mechanisms of pathogenesis; determinants of protective immunity; host range and tissue tropism in liver and GI tract pathogenic viruses and studies of vaccines in people."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Wang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9366&type=small&showNoImage","displayName":"Li Wang","firstName":"Li","href":"http://med.stanford.edu/profiles/Li_Wang","researchInterest":""},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Fathman","clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","displayName":"C. Garrison Fathman","firstName":"C","href":"http://med.stanford.edu/profiles/C_Fathman","researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have idintified a gene (GRAIL) that seems to control T cell anergy and are defining the regulatory T cell core transcriptome.  Additional studies are on the mechanism of effect of anti-CD3 antibodies in therapy of T1D."},{"lastName":"Butcher","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4498&type=small&showNoImage","displayName":"Eugene Butcher","firstName":"Eugene","href":"http://med.stanford.edu/profiles/Eugene_Butcher","researchInterest":"Our interests include: \r\n1) The physiology and significance of lymphocyte homing in local and systemic immunity; \r\n2) biochemical and genetic studies of molecules that direct leukocyte recruitment; \r\n3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; \r\n4) vascular differentiation in normal and pathologic inflammatory states; \r\n5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus (Active) Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","displayName":"Leonard Herzenberg","firstName":"Leonard","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC)."},{"lastName":"Mellins","clinicalFocus":[{"focus":"Pediatric Rheumatology"},{"focus":"Rheumatology, Pediatric"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Human Gene Therapy"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Human Gene Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5952&type=small&showNoImage","displayName":"Elizabeth Mellins","firstName":"Elizabeth","href":"http://med.stanford.edu/profiles/Elizabeth_Mellins","researchInterest":"Molecular mechanisms and intracellular pathways of antigen processing and presentation; structure/function of HLA-DR,-DM, -DO; HLA allele association with disease; pathogen evasion of the class II pathway."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","displayName":"Leonore A. Herzenberg","firstName":"Leonore","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays."},{"lastName":"Weissman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","displayName":"Irving Weissman","firstName":"Irving","href":"http://med.stanford.edu/profiles/Irving_Weissman","researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4282&type=small&showNoImage","displayName":"Mark M. Davis","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Davis","researchInterest":"Molecular mechanisms of lymphocyte recognition and differentiation; molecular genetics and expression of T-cell receptor genes.  Dynamics and functionality of specific T cell populations in human cancer."},{"lastName":"Lee","clinicalFocus":[{"focus":"Hematology"},{"focus":"Leukemia - Hematology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4564&type=small&showNoImage","displayName":"Peter P. Lee","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Lee","researchInterest":"Understanding the biology of cancer-T cell interactions."},{"lastName":"Foung","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4155&type=small&showNoImage","displayName":"Steven Foung","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Foung","researchInterest":"Our research focus is on the early events of hepatitis C virus infection- virus attachment and entry into susceptible cells. The approach is through the generation and functional studies of human monoclonal antibodies (HMAbs) to the virus envelope proteins with an emphasis on antibodies to conformational epitopes."},{"lastName":"Choi","clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Radiation Therapy"}],"appointments":[{"appointment":"Clinical Assistant Professor,Neurosurgery"}],"primaryAppointment":"Clinical Assistant Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8332&type=small&showNoImage","displayName":"Clara Y. Choi, M.D., Ph.D.","firstName":"Clara","href":"http://med.stanford.edu/profiles/Clara_Choi","researchInterest":""},{"lastName":"Kraft","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7184&type=small&showNoImage","displayName":"Daniel Kraft, MD","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Kraft","researchInterest":"-Stem cell biology & Regenerative Medicine\r\n\r\n-Stem Cell Derived Immunotherapy for Cancer\r\n\r\n-BioEngineering\r\n\r\n-The hematopoietic stem cell niche in murine and human systems\r\n\r\n-Human T cell differentiation\r\n\r\n-Humanized animal models\r\n\r\n-Clinical focus: Bone Marrow/Hematopoietic Stem cell transplantation for malignant and non-malignant diseases in adults & children\r\n\r\n-Medical devices to enable stem cell based regenerative medicine, to include marrow derived stem cell harvest, processing and delivery"}]}