{"result":[{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Chemistry Department"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","displayName":"James K. Chen","firstName":"James","href":"http://med.stanford.edu/profiles/James_Chen","researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Krasnow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","displayName":"Mark Krasnow","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Krasnow","researchInterest":"-  Lung development and stem cells\r\n-  Neural control of breathing\r\n-  Lung diseases including lung cancer\r\n-  New genetic model organisms for medicine"},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Samos","clinicalFocus":[],"appointments":[{"appointment":"Science Writer/Editor,Neurosurgery"},{"appointment":"Information Editor,Neurosurgery"}],"primaryAppointment":"Science Writer/Editor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=28093&type=small&showNoImage","displayName":"Cynthia Samos","firstName":"Cynthia","href":"http://med.stanford.edu/profiles/Cynthia_Samos","researchInterest":""},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Baker","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6206&type=small&showNoImage","displayName":"Bruce Baker","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Baker","researchInterest":""},{"lastName":"Okada","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurology & Neurological Sciences"}],"primaryAppointment":"Instructor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8191&type=small&showNoImage","displayName":"Ami Okada","firstName":"Ami","href":"http://med.stanford.edu/profiles/Ami_Okada","researchInterest":"Our interests are to understand the mechanism and control of signals that regulate proliferation and differentiation in adult tissue.  We are currently focused on studying modulation of the Hedgehog pathway in brain and muscle stem cell compartments during normal homeostasis and in degeneration or disease."},{"lastName":"Rohatgi","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Assistant Professor (By courtesy),Biochemistry"}],"primaryAppointment":"Assistant Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10885&type=small&showNoImage","displayName":"Rajat Rohatgi","firstName":"Rajat","href":"http://med.stanford.edu/profiles/Rajat_Rohatgi","researchInterest":"We are working to elucidate the biochemical and cell biological principles that govern signaling pathways that sit at the intersection between developmental biology and cancer.  Our toolkit combines bulk biochemical techniques, such as cell-free reconstitution, with microscopy using novel optical probes to study the dynamics of signal propagation in cells.  We strive to develop novel strategies for the manipulation of these pathways for cancer therapies and applications in regenerative medicine."},{"lastName":"Francke","clinicalFocus":[{"focus":"Neurogenetics"},{"focus":"Clinical Genetics"}],"appointments":[{"appointment":"Professor Emeritus,Genetics"},{"appointment":"Emeritus Faculty, Acad Council,Genetics"},{"appointment":"Professor,Pediatrics - Medical Genetics"}],"primaryAppointment":"Professor Emeritus,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care."},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Tobin","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Sr Research Scholar (PI Waiver),Pediatrics - Centers, Center for Biomedical Ethics"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6945&type=small&showNoImage","displayName":"Sara L. (Sally) Tobin","firstName":"Sara","href":"http://med.stanford.edu/profiles/Sara_Tobin","researchInterest":"Tobin is a Senior Research Scholar at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983 and moved to Stanford University in 1996. Her research contributions have been published in presti"},{"lastName":"Ruiz-Lozano","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Pediatrics - Cardiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Pediatrics - Cardiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18359&type=small&showNoImage","displayName":"Pilar Ruiz-Lozano, Ph.D.","firstName":"Pilar","href":"http://med.stanford.edu/profiles/Pilar_Ruiz-Lozano","researchInterest":"Cardiac development and repair"},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/Arend_Sidow","researchInterest":"We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Mourrain","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24313&type=small&showNoImage","displayName":"Philippe Mourrain","firstName":"Philippe","href":"http://med.stanford.edu/profiles/Philippe_Mourrain","researchInterest":""},{"lastName":"Jackson","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4463&type=small&showNoImage","displayName":"Peter Jackson","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Jackson","researchInterest":"Cell cycle and cyclin control of DNA replication ."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Olivares","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18321&type=small&showNoImage","displayName":"Gonzalo Olivares","firstName":"Gonzalo","href":"http://med.stanford.edu/profiles/Gonzalo_Olivares","researchInterest":"Stem cells are unique in that can renew themselves through cell division or differentiate into a diverse range of specialized cell types.  I will study genes that functions to prevent the growth of tumors and regulates stem cell decisions. Understanding the molecular mechanisms that mediate the choice between self-renewal and differentiation in stem cells has important implications for many areas of biology, including ancer treatment, regenerative medicine and new cell-based therapies."},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."}]}