{"result":[{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"Kerchner","clinicalFocus":[{"focus":"Alzheimer's Disease"},{"focus":"Mild Cognitive Impairment"},{"focus":"Dementia"},{"focus":"Behavioral Neurology"},{"focus":"Neurodegenerative Disease"},{"focus":"Neuropsychology"},{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15338&type=small&showNoImage","displayName":"Geoffrey Kerchner","firstName":"Geoffrey","href":"http://med.stanford.edu/profiles/Geoffrey_Kerchner","researchInterest":"Dr. Kerchner is a behavioral neurologist who cares for patients with Alzheimer's disease and other age-related neurodegenerative illnesses. He studies the use of ultra-high field MRI and other advanced neuroimaging technologies to reveal how these diseases affect the microscopic structure and circuitry of the brain, with the intent of creating new strategies for early diagnosis. Dr. Kerchner also supervises the participation of patients in clinical trials for Alzheimer\u0092s disease."},{"lastName":"Yeomans","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3855&type=small&showNoImage","displayName":"David C. Yeomans","firstName":"David","href":"http://med.stanford.edu/profiles/David_Yeomans","researchInterest":"Physiology of different pain types; Biomarkers of pain and inflammation; Gene Therapy for Pain"},{"lastName":"Trudell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4617&type=small&showNoImage","displayName":"James Trudell","firstName":"James","href":"http://med.stanford.edu/profiles/James_Trudell","researchInterest":"Molecular theories of anesthesia. My emphasis is on the molecular interactions of inhalational anesthetics and alcohol. I perform computational chemistry simulations on how these molecules bind to putative receptor sites. I am also interested in modeling receptor proteins in which chimeras cause loss or enhancement of anesthetic sensitivity."},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Bertaccini","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Professor - Med Center Line,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4079&type=small&showNoImage","displayName":"Edward Bertaccini","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Bertaccini","researchInterest":"molecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels"},{"lastName":"Rothwell","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=16662&type=small&showNoImage","displayName":"Patrick Rothwell","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Rothwell","researchInterest":""},{"lastName":"Martucci","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Anesthesia"}],"primaryAppointment":"Postdoctoral Research fellow, Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25052&type=small&showNoImage","displayName":"Katherine (Katie) Martucci","firstName":"Katherine","href":"http://med.stanford.edu/profiles/Katherine_Martucci","researchInterest":""},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20934&type=small&showNoImage","displayName":"Lu Chen","firstName":"Lu","href":"http://med.stanford.edu/profiles/Lu_Chen","researchInterest":"What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."},{"lastName":"Doufas","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Neurosurgical Anesthesia"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7905&type=small&showNoImage","displayName":"Anthony G. Doufas, M.D., Ph.D.","firstName":"Anthony","href":"http://med.stanford.edu/profiles/Anthony_Doufas","researchInterest":"My research focuses on the relationship between sleep abnormalities and pain behavior and opioid pharmacology in the postoperative, as well as chronic pain setting. More  specifically, I am interested in delineating the effect of the different components of sleep-diosordered breathing, like nocturnal recurrent hypoxemia and sleep fragmentation on pain behavior in the acute and/or chronic care setting."},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35683&type=small&showNoImage","displayName":"Dong Li","firstName":"Dong","href":"http://med.stanford.edu/profiles/Dong_Li","researchInterest":""},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"Pacharinsak","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Comparative Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=28355&type=small&showNoImage","displayName":"Cholawat Pacharinsak","firstName":"Cholawat","href":"http://med.stanford.edu/profiles/Cholawat_Pacharinsak","researchInterest":""},{"lastName":"Mochly-Rosen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","displayName":"Daria Mochly-Rosen","firstName":"Daria","href":"http://med.stanford.edu/profiles/Daria_Mochly-Rosen","researchInterest":"Two areas:  1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling.  We focus on protein kinase C (PKC)-mediated signal transduction and on mitochondrial dynamics in several disease models. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, we study their involvement  in normal cells and in models of human diseases."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20866&type=small&showNoImage","displayName":"Lulu Chen","firstName":"Lulu","href":"http://med.stanford.edu/profiles/Lulu_Chen","researchInterest":""},{"lastName":"Giocomo","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35065&type=small&showNoImage","displayName":"Lisa Giocomo","firstName":"Lisa","href":"http://med.stanford.edu/profiles/Lisa_Giocomo","researchInterest":"My laboratory studies the cellular and molecular mechanisms underlying the organization of cortical circuits important for spatial navigation and memory. We are particularly focused on medial entorhinal cortex, where many neurons fire in spatially specific patterns and thus offer a measurable output for molecular manipulations. We combine electrophysiology, genetic approaches and behavioral paradigms to unravel the mechanisms and behavioral relevance of non-sensory cortical organization. Our fi"},{"lastName":"Scherrer","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Anesthesia"},{"appointment":"Assistant Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=32474&type=small&showNoImage","displayName":"Gregory Scherrer","firstName":"Gregory","href":"http://med.stanford.edu/profiles/Gregory_Scherrer","researchInterest":"Our laboratory investigates the cellular and molecular mechanisms of pain and its control by opioids. When chronic, pain is no longer an essential warning system critical to our survival, but a disease that severely affects the quality of life of many patients. We search to identity the neurons that participate in generating the sensation of pain and the molecular mechanisms that regulate neural activity in pain circuits to develop novel analgesic strategies against pathological pain."},{"lastName":"Tinklenberg","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Clinical Assistant Professor,Psychiatry & Behavioral Science - Vaden Health Center"}],"primaryAppointment":"Clinical Assistant Professor,Psychiatry & Behavioral Science - Vaden Health Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7065&type=small&showNoImage","displayName":"Julie Tinklenberg","firstName":"Julie","href":"http://med.stanford.edu/profiles/Julie_Tinklenberg","researchInterest":""},{"lastName":"Iyer","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Bioengineering"}],"primaryAppointment":"Ph.D., Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20188&type=small&showNoImage","displayName":"Shrivats Iyer","firstName":"Shrivats","href":"http://med.stanford.edu/profiles/Shrivats_Iyer","researchInterest":""},{"lastName":"Angelotti","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4339&type=small&showNoImage","displayName":"Timothy Angelotti MD, PhD","firstName":"Timothy","href":"http://med.stanford.edu/profiles/Timothy_Angelotti","researchInterest":"My research efforts are focused on investigating the pharmacological and physiological interface of the autonomic nervous system with effector organs. Utilizing molecular, cellular, and electrophysiological techniques, we are examining alpha2 adrenergic receptor function in cultured sympathetic neurons. Future research aims will be directed toward understanding neurotransmitter release in general."},{"lastName":"Nemenov","clinicalFocus":[],"appointments":[{"appointment":"Consulting Professor,Anesthesia"}],"primaryAppointment":"Consulting Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6022&type=small&showNoImage","displayName":"Mikhail I. Nemenov","firstName":"Mikhail","href":"http://med.stanford.edu/profiles/Mikhail_Nemenov","researchInterest":"Physics and physiology of laser and heat nerve stimulation, pain and cutaneous sensations."},{"lastName":"Luoma","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24597&type=small&showNoImage","displayName":"Jessie Luoma","firstName":"Jessie","href":"http://med.stanford.edu/profiles/Jessie_Luoma","researchInterest":""},{"lastName":"Krane","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Anesthesia, Pediatric"},{"focus":"Complex Regional Pain Syndromes"}],"appointments":[{"appointment":"Professor - Med Center Line,Anesthesia"},{"appointment":"Professor - Med Center Line,Pediatrics"}],"primaryAppointment":"Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4216&type=small&showNoImage","displayName":"Elliot J. Krane","firstName":"Elliot","href":"http://med.stanford.edu/profiles/Elliot_Krane","researchInterest":"The management of pain in children using intraspinal opioids, regional anesthetics, and novel analgesic agents; cerebral and osmolar complications of diabetic ketoacidosis in children."},{"lastName":"Jackson","clinicalFocus":[{"focus":"Neurological Surgery"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7251&type=small&showNoImage","displayName":"Paul Jackson, MD, Ph.D.","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Jackson","researchInterest":""}]}