{"result":[{"researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Shoshana_Levy","appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Shoshana","primaryAppointment":"Professor (Research),Medicine - Oncology","displayName":"Shoshana Levy","lastName":"Levy"},{"researchInterest":"Dr. Cheung's research interests focus on liver diseases, with emphasis on viral hepatitis. His past research include investigating the mechanism of viral neutralization of hepatitis B virus at the molecular level and immune response to hepatitis C virus. Dr. Cheung is studing various aspects of hepatitis C, both clinical and translational research.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4732&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ramsey_Cheung","appointments":[{"appointment":"Professor - Med Center Line,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Hepatology (Liver)"}],"firstName":"Ramsey","primaryAppointment":"Professor - Med Center Line,Medicine - Gastroenterology & Hepatology","displayName":"Ramsey Cheung","lastName":"Cheung"},{"researchInterest":"Our laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells  in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4188&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ann_Arvin","appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"firstName":"Ann","primaryAppointment":"Professor,Pediatrics - Infectious Diseases","displayName":"Ann M. Arvin","lastName":"Arvin"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9992&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Shirit_Einav","appointments":[{"appointment":"Instructor,Medicine - Infectious Diseases"}],"clinicalFocus":[],"firstName":"Shirit","primaryAppointment":"Instructor,Medicine - Infectious Diseases","displayName":"Shirit Einav","lastName":"Einav"},{"researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Edgar_Engleman","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Edgar","primaryAppointment":"Professor,Pathology","displayName":"Edgar Engleman","lastName":"Engleman"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"},{"researchInterest":"Dr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Other interests include exploitation of hepatic stem cells, engineered human liver tissues, and new biodefense antiviral strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4576&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jeffrey_Glenn","appointments":[{"appointment":"Associate Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Gastroenterology"}],"firstName":"Jeffrey","primaryAppointment":"Associate Professor,Medicine - Gastroenterology & Hepatology","displayName":"Jeffrey S.  Glenn, M.D., Ph.D.","lastName":"Glenn"},{"researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Leonore","primaryAppointment":"Professor (Research),Genetics","displayName":"Leonore A. Herzenberg","lastName":"Herzenberg"},{"researchInterest":"Research focusses on one of the human herpesviruses: cytomegalovirus (CMV). This virus is a major medical problem in immunocompromised individuals. The virus is very large, carrying over 200 genes. We have characterized functions involved in viral growth (regulation of gene expression, replication, genome packaging) and pathogenesis (tissue tropism, latency). Molecular genetic and biochemical approaches have been employed to dissect these functions.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4146&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Edward_Mocarski","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Edward","primaryAppointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology","displayName":"Edward Mocarski","lastName":"Mocarski"},{"researchInterest":"Molecular mechanisms of lymphocyte recognition and differentiation; molecular genetics and expression of T-cell receptor genes.  Dynamics and functionality of specific T cell populations in human cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4282&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Davis","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Mark M. Davis","lastName":"Davis"},{"researchInterest":"Enhancement of transfusion safety and effectiveness, with a focus on quality assurance in transfusion therapy; transfusion medicine education; pediatric and adult transfusion therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4139&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_Galel","appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Pediatric Hematology-Oncology"}],"firstName":"Susan","primaryAppointment":"Associate Professor - Med Center Line,Pathology","displayName":"Susan Galel","lastName":"Galel"},{"researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Chris_Garcia","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Chris","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Chris Garcia","lastName":"Garcia"},{"researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jane_Parnes","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jane","primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","displayName":"Jane Parnes","lastName":"Parnes"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9514&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mike_Reichelt","appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"clinicalFocus":[],"firstName":"Mike","primaryAppointment":"Postdoctoral Research fellow, Pediatrics","displayName":"Mike Reichelt","lastName":"Reichelt"},{"researchInterest":"Clinical Interests: lymphoma. Research Interests: Immunology and molecular biology of lymphoid malignancy; molecular vaccines for cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4608&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ronald_Levy","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Lymphoma "},{"focus":"Non-Hodgkin's Lymphoma"},{"focus":"Non-Hodgkin's Lymphoma - Medical Oncology"},{"focus":"Burkitt's Lymphoma"},{"focus":"Burkitt's Lymphoma - Medical Oncology"},{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Burkitt's Lymphoma - Hematology"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"Non-Hodgkin's Lymphoma - Hematology"}],"firstName":"Ronald","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Ronald Levy, MD","lastName":"Levy"},{"researchInterest":"My research program is currently focused in three areas: 1) translational research (HCV/HIV viral evolution and antiviral resistance prevalence and development), 2) HIV/HCV clinical trials (diagnostic assay/medical device, antiretrovirals, ARVs and immunomodulators), and 3) health services research focusing on cost effectiveness of HIV antibody and ARV resistance testing and ARV utilization and clincal outcome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4021&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Holodniy","appointments":[{"appointment":"Professor - Med Center Line,Medicine - Infectious Diseases"}],"clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"}],"firstName":"Mark","primaryAppointment":"Professor - Med Center Line,Medicine - Infectious Diseases","displayName":"Mark Holodniy","lastName":"Holodniy"},{"researchInterest":"We have recently cloned a novel NK cell receptor which is likely involved in the activation of NK cells and are characterizing the expression and effector functions of this receptor in the context of transplantation. In related studies the role of NK cells in alloreactivity is being examined. Pathways of apoptosis, especially the pro-apoptotic molecule BID, is being studied in hepatocytes and allogeneic liver grafts","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4475&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Sheri_Krams","appointments":[{"appointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Sheri","primaryAppointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation","displayName":"Sheri Krams","lastName":"Krams"},{"researchInterest":"Translational bioinformatics and molecular virology of hepatitis C. \r\n\r\nMy work focuses on two broad areas: (a) using computational/statistical techniques, including phylogenomic analysis and monte carlo simulation, to study viral-host interactions; (b) using molecular virology techniques to study hepatitis C replication and pathogensis","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9916&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Phillip_Pang","appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"clinicalFocus":[],"firstName":"Phillip","primaryAppointment":"Postdoctoral Medical fellow, Medicine","displayName":"Phillip S. Pang","lastName":"Pang"},{"researchInterest":"Cell death pathways in EBV B cell lymphomas; role of cytokines and immunosuppression in growth and survival of EBV B cell lymphomas; cytokine pathways in graft rejection; identification of regulatory T cell subsets in alloreactivity; role of co-stimulation in alloreactivity; ","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Olivia_Martinez","appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Olivia","primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","displayName":"Olivia Martinez","lastName":"Martinez"},{"researchInterest":"Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6393&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jennifer_Cochran","appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jennifer","primaryAppointment":"Assistant Professor,Bioengineering","displayName":"Jennifer R. Cochran","lastName":"Cochran"},{"researchInterest":"Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4458&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Peter_Sarnow","appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Peter","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Peter Sarnow","lastName":"Sarnow"},{"researchInterest":"Our laboratory focuses on host-viral interactions in the sexual and mother-to-child transmission of HIV-1. We developed human organotypic models to closely mimic in vivo infection. Our recent work has focused on developing immune-based and small molecule inhibitors of HIV-1 transmission.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3975&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Bruce_Patterson","appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Medicine"}],"clinicalFocus":[],"firstName":"Bruce","primaryAppointment":"Associate Professor - Med Center Line,Pathology","displayName":"Bruce Patterson","lastName":"Patterson"},{"researchInterest":"Molecular mechanisms of pathogenesis; determinants of protective immunity; host range and tissue tropism in liver and GI tract pathogenic viruses and studies of vaccines in people.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3791&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Harry_Greenberg","appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Harry","primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","displayName":"Harry B Greenberg","lastName":"Greenberg"},{"researchInterest":"My laboratory has two major research interests.  First, to define cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies.  Second, to determine how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants, with a particular focus on anti-viral vaccines.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4439&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_Lewis","appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"firstName":"David","primaryAppointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology","displayName":"David B. Lewis","lastName":"Lewis"}]}