{"result":[{"lastName":"Yue","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8441&type=small&showNoImage","displayName":"Patrick Yue","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Yue","researchInterest":"My primary research focus has been the mechanisms of insulin resistance and diabetes as they pertain to the heart.  I am particularly interested in the potential involvement of the recently discovered peptide hormone apelin.  Recent studies in my laboratory group have focused on apelin's role in promoting insulin sensitivity on the systemic, tissue-specific, and cellular level.  We are currently investigating apelin-mediated signaling events in insulin-sensitive and -resistant cardiac muscle."},{"lastName":"Sheikh","clinicalFocus":[{"focus":"Cardiothoracic Surgery and Transplantation"},{"focus":"Mechanical Circulatory Support"},{"focus":"General Surgery"}],"appointments":[{"appointment":"Clinical Instructor,Cardiothoracic Surgery - Adult Cardiac Surgery"}],"primaryAppointment":"Clinical Instructor,Cardiothoracic Surgery - Adult Cardiac Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35536&type=small&showNoImage","displayName":"Ahmad Sheikh","firstName":"Ahmad","href":"http://med.stanford.edu/profiles/Ahmad_Sheikh","researchInterest":"Molecular imaging of cardiac stem cell therapy\r\nHeart failure\r\nCardiothoracic Transplantation\r\nSurgical Education"},{"lastName":"Spin","clinicalFocus":[{"focus":"Aortic Disease"},{"focus":"Marfan Syndrome and Aortic Disorders"},{"focus":"Cardiovascular Disease"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Clinical Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6448&type=small&showNoImage","displayName":"Joshua M. Spin","firstName":"Joshua","href":"http://med.stanford.edu/profiles/Joshua_Spin","researchInterest":"Dr. Spin began his research career studying the structural biology of low density lipoprotein, and has been augmenting his skills with intensive training in molecular biology techniques, particularly those involving high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development and vascular disease. His latest work has focused on the biology of aortic aneurysms."},{"lastName":"Leeper","clinicalFocus":[{"focus":"Vascular Medicine"},{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Surgery - Vascular Surgery"},{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Surgery - Vascular Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9669&type=small&showNoImage","displayName":"Nicholas Leeper","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_Leeper","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18501&type=small&showNoImage","displayName":"Wing Tak Jack Wong","firstName":"Wing Tak Jack","href":"http://med.stanford.edu/profiles/Wing Tak Jack_Wong","researchInterest":""},{"lastName":"Connolly","clinicalFocus":[{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6324&type=small&showNoImage","displayName":"Andrew J. Connolly","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Connolly","researchInterest":"My research interests are vascular biology and cardiovascular pathology.  We are currently working on gene expression in endothelial cells at sites of pathology."},{"lastName":"Wang","clinicalFocus":[{"focus":"Interventional Radiology"},{"focus":"Diagnostic Radiology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Radiology - Diagnostic Radiology"}],"primaryAppointment":"Clinical Assistant Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24317&type=small&showNoImage","displayName":"David S. Wang","firstName":"David","href":"http://med.stanford.edu/profiles/David_Wang","researchInterest":""},{"lastName":"McLaughlin","clinicalFocus":[{"focus":"Endocrinology / Diabetes"},{"focus":"Endocrinology and Metabolism"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Endocrinology, Gerontology, & Metabolism"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6107&type=small&showNoImage","displayName":"Tracey McLaughlin","firstName":"Tracey","href":"http://med.stanford.edu/profiles/Tracey_McLaughlin","researchInterest":"Dr. McLaughlin conducts a number of clinical research studies related to obesity, insulin resistance, diabetes, and cardiovascular disease. Current studies include: 1) the impact of macronutrient composition on weight loss and cardiocascular risk (diabetic and nondiabetic patients); 2) comparison of weight loss and cardiovascular risk reduction in diabetic patients treated with different classes of antihyperglycemic drugs; 3) the role of the adipocyte in modulating insulin resistance"},{"lastName":"Ashley","clinicalFocus":[{"focus":"Cardiology"},{"focus":"Inherited cardiovascular disease"},{"focus":"Heart Failure"},{"focus":"Genomic medicine"},{"focus":"Hypertrophic Cardiomyopathy"},{"focus":"Cardiomyopathy, Dilated"},{"focus":"Arrhythmogenic Right Ventricular Dysplasia"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7578&type=small&showNoImage","displayName":"Euan A. Ashley","firstName":"Euan","href":"http://med.stanford.edu/profiles/Euan_Ashley","researchInterest":"The Ashley lab is focused on the application of genomics to medicine. We develop methods for the interpretation of whole genome sequencing data to improve diagnosis of genetic disease and to personalize the practice of medicine. We also use RNA sequencing data to generate gene networks and link communities. Half of the lab is wet benches where we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality of our favorite targets."},{"lastName":"McConnell","clinicalFocus":[{"focus":"Coronary Artery Disease"},{"focus":"Preventive Cardiology"},{"focus":"Cardiovascular Imaging"},{"focus":"Mobile Health"},{"focus":"Cardiovascular Disease"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Professor - Med Center Line (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Professor - Med Center Line (By courtesy),Electrical Engineering"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4727&type=small&showNoImage","displayName":"Michael V. McConnell, MD, MSEE","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_McConnell","researchInterest":"Clinical and molecular Imaging of cardiovascular disease, with a focus on coronary and vascular diseases, including atherosclerosis, aortic aneurysms, and vascular inflammation."},{"lastName":"Fischbein","clinicalFocus":[{"focus":"Cardiothoracic Surgery"},{"focus":"Aortic Diseases"},{"focus":"Thoracic Surgery"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Cardiothoracic Surgery - Adult Cardiac Surgery"}],"primaryAppointment":"Assistant Professor - Med Center Line,Cardiothoracic Surgery - Adult Cardiac Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7579&type=small&showNoImage","displayName":"Michael Fischbein","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Fischbein","researchInterest":"Molecular and genetic mechanisms of aortic aneurysm/dissection development. Molecular mechanisms of aneurysm formation in Marfan Syndrome. Clinical research interests include thoracic aortic diseases (aneurysms, dissections)."},{"lastName":"Liu","clinicalFocus":[{"focus":"Diabetes andMetabolism"},{"focus":"Endocrinology"}],"appointments":[{"appointment":"Instructor,Medicine - Endocrinology, Gerontology, & Metabolism"}],"primaryAppointment":"Instructor,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9280&type=small&showNoImage","displayName":"Alice Liu","firstName":"Alice","href":"http://med.stanford.edu/profiles/Alice_Liu","researchInterest":""},{"lastName":"Xu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17499&type=small&showNoImage","displayName":"Shi-Ming Xu, Ph.D.","firstName":"Shi Ming","href":"http://med.stanford.edu/profiles/Shi Ming_Xu","researchInterest":"The cardioactive peptide apelin has been shown to improve insulin sensitivity systemically. however, its effects on cardiac metabolism are unknown.My current research interests are to uncover the role of apelin and its downstream signaling intermediates in the pathogenesis of diabetic cardiomyopathy."},{"lastName":"Zarafshar","clinicalFocus":[{"focus":"Internal Medicine"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - General Medical Disciplines"}],"primaryAppointment":"Clinical Instructor,Medicine - General Medical Disciplines","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36463&type=small&showNoImage","displayName":"Shirin Zarafshar","firstName":"Shirin","href":"http://med.stanford.edu/profiles/Shirin_Zarafshar","researchInterest":""},{"lastName":"Patterson","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care Medicine"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Surgery"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6059&type=small&showNoImage","displayName":"Andrew J. Patterson, M.D., Ph.D.","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Patterson","researchInterest":"Critical Care Medicine,\r\nCardiovascular Pharmacology,\r\nAdrenergic Receptors,\r\nCongestive Heart Failure,\r\nVascular Biology,\r\nCardiopulmonary Physiology,\r\nSepsis"},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20850&type=small&showNoImage","displayName":"Won Hee Lee","firstName":"Won Hee","href":"http://med.stanford.edu/profiles/Won Hee_Lee","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Farquhar","clinicalFocus":[{"focus":"Cardiology (Heart), Preventive"},{"focus":"Cardiovascular Medicine"},{"focus":"Chronic Disease Prevention"},{"focus":"Global cancer prevention"}],"appointments":[{"appointment":"Professor Emeritus,Medicine - Stanford Prevention Research Center"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Stanford Prevention Research Center"}],"primaryAppointment":"Professor Emeritus,Medicine - Stanford Prevention Research Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5956&type=small&showNoImage","displayName":"John W. Farquhar, M.D.","firstName":"John","href":"http://med.stanford.edu/profiles/John_Farquhar","researchInterest":"Disease prevention, epidemiology of cardiovascular diseases, community-based education for disease prevention, international health."},{"lastName":"Yeung","clinicalFocus":[{"focus":"Cardiology (Heart)"},{"focus":"Cardiovascular Disease"},{"focus":"Coronary Artery Disease"},{"focus":"Chronic Total Occlusions"},{"focus":"Complex Coronary Angioplasty"},{"focus":"Mitral Valvuloplasty"},{"focus":"Percutaneous Aortic Valve Replacement"},{"focus":"Interventional Cardiology"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4228&type=small&showNoImage","displayName":"Alan Yeung, MD","firstName":"Alan","href":"http://med.stanford.edu/profiles/Alan_Yeung","researchInterest":"Coronary artery disease is the leading cause of death in men and women in the United States. Our group is interested in studying both the early and late phases of atherosclerosis so that we can better develop prevention and treatment strategies."},{"lastName":"Gardner","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Medicine - Stanford Prevention Research Center"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor (Research),Medicine - Stanford Prevention Research Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4085&type=small&showNoImage","displayName":"Christopher Gardner","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Gardner","researchInterest":"The role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines"},{"lastName":"Haskell","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Medicine - Stanford Prevention Research Center"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Stanford Prevention Research Center"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor Emeritus,Medicine - Stanford Prevention Research Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6108&type=small&showNoImage","displayName":"William Haskell","firstName":"William","href":"http://med.stanford.edu/profiles/William_Haskell","researchInterest":"My major research interests and activities over the next several years will focus on the development and evaluation of the objective measurement of physical activity in free-living populations using a variety of sensing devices and mobile phones for data collection and processing. Also, I will continue to direct the Stanford Heart Network with the major mission being to assist community-based CVD prevention/treatment programs implement more effective heart attack and stroke prevention programs."},{"lastName":"Mochly-Rosen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","displayName":"Daria Mochly-Rosen","firstName":"Daria","href":"http://med.stanford.edu/profiles/Daria_Mochly-Rosen","researchInterest":"Two areas:  1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling.  We focus on protein kinase C (PKC)-mediated signal transduction and on mitochondrial dynamics in several disease models. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, we study their involvement  in normal cells and in models of human diseases."}]}