{"result":[{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9455&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kelly_Monk","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Kelly","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Kelly Monk","lastName":"Monk"},{"researchInterest":"Stem cell function requires both the establishment and maintenance of particular epigenetic states. Perturbation of the epigenetic status of stem cells may compromise both self-renewal and multipotency. Work from our lab has identified the Forkhead family transcription factor, FoxO3, as a regulator of adult neural stem cell (NSCs) quiescence, which prevents the depletion of this population of cells. Along with recent evidence that Forkhead family members act as \u0091pioneer factors\u0092 in the opening ","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9984&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ashley_Webb","appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"clinicalFocus":[],"firstName":"Ashley","primaryAppointment":"Postdoctoral Research fellow, Genetics","displayName":"Ashley Webb","lastName":"Webb"},{"researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Chen","appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Assistant Professor (By courtesy),Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Assistant Professor,Chemical and Systems Biology","displayName":"James K. Chen","lastName":"Chen"},{"researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Matthew_Scott","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Matthew","primaryAppointment":"Professor,Developmental Biology","displayName":"Matthew Scott","lastName":"Scott"},{"researchInterest":"Dr. Helms' research interests center around craniofacial development and regenerative medicine.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6152&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jill_Helms","appointments":[{"appointment":"Associate Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Jill","primaryAppointment":"Associate Professor,Surgery - Plastic/Recon Surgery","displayName":"Jill Helms","lastName":"Helms"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10397&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Rothenberg","appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Postdoctoral Medical fellow, Medicine","displayName":"Michael Rothenberg","lastName":"Rothenberg"},{"researchInterest":"Craniofacial development and  patterning","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9172&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Samantha_Brugmann","appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"clinicalFocus":[],"firstName":"Samantha","primaryAppointment":"Postdoctoral Research fellow, Surgery","displayName":"Samantha Brugmann","lastName":"Brugmann"},{"researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ben_Barres","appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"clinicalFocus":[],"firstName":"Ben","primaryAppointment":"Professor,Neurobiology","displayName":"Ben Barres","lastName":"Barres"},{"researchInterest":"Most types of congenital and acquired hearing loss arise from damage to, or loss of hair cells, the sensory cells of the inner ear.  Our recent work has focused on generating inner ear cell types from stem cells and we are interested in signaling pathways that control hair cell and auditory neuron (re-)generation in vitro and in vivo.  In a second line of research, we are working on the identification and the molceular characterization of proteins that are important for hair cell function.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7084&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stefan_Heller","appointments":[{"appointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Associate Professor (By courtesy),Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Stefan","primaryAppointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)","displayName":"Stefan Heller","lastName":"Heller"},{"researchInterest":"Sensorineural hearing loss affects more than 30 million people worldwide and the most common underlying pathology is loss of sensory hair cells, the mechanoreceptors of the inner ear.  Loss of these specialized cells is permanent in mammals and regeneration is limited/non-existent.  Recently stem cell-like cells have been isolated from the mammalian inner ears.\r\n\r\nOur research group is interested in identifying signals that maintain the stem cell population and the stem cell niche in the mammal","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8272&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Alan_Cheng","appointments":[{"appointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)"}],"clinicalFocus":[{"focus":"Otolaryngology"},{"focus":"Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)"},{"focus":"Cholesteotoma"},{"focus":"Hearing loss"},{"focus":"Branchial Cleft Cyst"},{"focus":"Head and Neck Neoplasms"}],"firstName":"Alan","primaryAppointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)","displayName":"Alan G. Cheng","lastName":"Cheng"},{"researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5928&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_McConnell","appointments":[{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Susan","primaryAppointment":"Member,Bio-X","displayName":"Susan McConnell","lastName":"McConnell"},{"researchInterest":"The biochemistry and molecular genetics of growth and differentiation of nerve cells. The structure, biosynthesis and mechanism of action of nerve growth factor and other neurotrophins. Gene regulation in target organs and glial cells during nerve regeneration. The role of apolipoproteins and of the myelin protein PMP-22 during nerve degeneration and regeneration and in peripheral neuropathies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3996&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Eric_Shooter","appointments":[{"appointment":"Emeritus (Active) Professor,Neurobiology"}],"clinicalFocus":[],"firstName":"Eric","primaryAppointment":"Emeritus (Active) Professor,Neurobiology","displayName":"Eric Shooter","lastName":"Shooter"},{"researchInterest":"My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues.  We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues.  The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the devel","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ching-Pin_Chang","appointments":[{"appointment":"Assistant Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ching-Pin","primaryAppointment":"Assistant Professor,Medicine - Cardiovascular Medicine","displayName":"Ching-Pin Chang","lastName":"Chang"},{"researchInterest":"My laboratory uses a variety of genetic, cellular, and molecular approaches to study skeletal development in humans, mice, and  fish. Many of our studies begin with naturally occuring genetic traits that alter skeletal development. By isolating the genes responsible for these traits, it has been possible to identify key pathways that control creation of skeletal tissue, repair of fractures, susceptibility to arthritis, and dramatic modifications of skeletal morphology during vertebrate evolution","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4193&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_Kingsley","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Professor,Developmental Biology","displayName":"David Kingsley","lastName":"Kingsley"},{"researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Roeland_Nusse","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Roeland","primaryAppointment":"Professor,Developmental Biology","displayName":"Roeland Nusse","lastName":"Nusse"},{"researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Uta_Francke","appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"firstName":"Uta","primaryAppointment":"Professor,Genetics","displayName":"Uta Francke","lastName":"Francke"},{"researchInterest":"I am interested in understanding the signaling pathways that regulate the development of specialized tight junctions in brain endothelial cells responsible for forming the blood-brain barrier. The identification of these signals is important for elucidating the mechanisms that regulate the entry of distinct compounds or drugs into the Central Nervous System (CNS) and the etiology of pathological CNS conditions associated with blood-brain barrier breakdown.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9742&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Dritan_Agalliu","appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"clinicalFocus":[],"firstName":"Dritan","primaryAppointment":"Postdoctoral Research fellow, Neurobiology","displayName":"Dritan Agalliu PhD","lastName":"Agalliu"},{"researchInterest":"Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4159&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Margaret_Fuller","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Margaret","primaryAppointment":"Professor,Developmental Biology","displayName":"Margaret T. Fuller","lastName":"Fuller"},{"researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Isabella_Graef","appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Isabella","primaryAppointment":"Assistant Professor,Pathology","displayName":"Isabella Graef","lastName":"Graef"},{"researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Cleary","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Professor,Pathology","displayName":"Michael Cleary","lastName":"Cleary"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9759&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Kryn_Stankunas","appointments":[{"appointment":"Instructor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Kryn","primaryAppointment":"Instructor,Medicine - Cardiovascular Medicine","displayName":"Kryn Stankunas","lastName":"Stankunas"},{"researchInterest":"The Reijo Pera Laboratory is focused on understanding key cell fates in the embryo, including the generation of pluripotent stem cells, somatic and germ cell lineages","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8036&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Renee_Reijo-Pera","appointments":[{"appointment":"Professor,Obstetrics & Gynecology - OB GYN Institutes"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Renee","primaryAppointment":"Professor,Obstetrics & Gynecology - OB GYN Institutes","displayName":"Renee A. Reijo Pera, Ph.D.","lastName":"Reijo-Pera"},{"researchInterest":"Our lab focuses on how inflammatory responses after brain injury affect neurological recovery. We utilize translational approaches to understand molecular mechanisms underlying functional recovery.  Molecular events are modified in mice using either transgenic models or novel small molecule compounds, and then we evaluate the effects on functional recovery as well as on cellular and molecular responses.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6463&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Marion_Buckwalter","appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Member,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Marion","primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","displayName":"Marion S. Buckwalter","lastName":"Buckwalter"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"Genetic and molecular basis of respiratory system  development, maintenance, and disease in Drosophila, mouse, and human","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Krasnow","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Biochemistry","displayName":"Mark Krasnow","lastName":"Krasnow"}]}