{"result":[{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9061&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Julia_Pak","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Julia","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Julia Pak","lastName":"Pak"},{"researchInterest":"We study the functional and structural signals that govern mRNA decay and gene expression in bacteria, as well as mechanisms affecting aging and the ability of mammalian cells to support the propagation of viruses.  A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of gene expression on a genome-wide basis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4481&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stanley_Cohen","appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Stanley","primaryAppointment":"Professor,Genetics","displayName":"Stanley N. Cohen, MD","lastName":"Cohen"},{"researchInterest":"Molecular and cellular mechanisms that control muscle and neuronal growth; stem cell biology, differentiation, and tumorigenicity. Regulating stem cell fate in vitro and in vivo. Stem cell therapies. Hematopoietic and muscle stem cells. Characterizing and bioengineering stem cell niches. Nuclear reprogramming. Muscle development and disease. Drug delivery. Tracking cell behavior in vitro and in vivo. Understanding tissue degeneration and regeneration.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4517&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Helen_Blau","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Helen","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Helen M. Blau","lastName":"Blau"},{"researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Matthew_Scott","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Matthew","primaryAppointment":"Professor,Developmental Biology","displayName":"Matthew Scott","lastName":"Scott"},{"researchInterest":"Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4458&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Peter_Sarnow","appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Peter","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Peter Sarnow","lastName":"Sarnow"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9706&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ayelet-Taly_Lamm","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Ayelet-Taly","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Ayelet Lamm (Margalit)","lastName":"Lamm"},{"researchInterest":"Mechanisms underlying homologous chromosome pairing, DNA recombination and chromosome remodeling during meiosis, using the nematode Caenorhabditis elegans as an experimental system.  High-resolution 3-D imaging of dynamic reorganization of chromosome architecture.  Role of protease inhibitors in regulating sperm activation.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4035&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anne_Villeneuve","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Anne","primaryAppointment":"Professor,Developmental Biology","displayName":"Anne Villeneuve","lastName":"Villeneuve"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9557&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Dan_Cao","appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"clinicalFocus":[],"firstName":"Dan","primaryAppointment":"Postdoctoral Research fellow, Pediatrics","displayName":"Dan Cao","lastName":"Cao"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10159&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Andrew_Yoo","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Andrew","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Andrew Yoo","lastName":"Yoo"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"Chromatin structure and function:\r\n- packaging of DNA\r\n- regulation of transcription\r\n- epigenetic signals affecting functional state of chromatin\r\n- statistical methods for analysis of high-throughput sequencing data.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10035&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anton_Valouev","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Anton","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Anton Valouev","lastName":"Valouev"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"We study the function and molecular evolution of proteins and noncoding functional elements in the genome.  Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Arend_Sidow","appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Arend","primaryAppointment":"Associate Professor,Pathology","displayName":"Arend Sidow","lastName":"Sidow"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6206&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Bruce_Baker","appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Bruce","primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","displayName":"Bruce Baker","lastName":"Baker"},{"researchInterest":"Genetic and molecular basis of respiratory system  development, maintenance, and disease in Drosophila, mouse, and human","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Krasnow","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Biochemistry","displayName":"Mark Krasnow","lastName":"Krasnow"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9884&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mara_Schvarzstein","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Mara","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Mara Schvarzstein","lastName":"Schvarzstein"},{"researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ronald_Davis","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Ronald","primaryAppointment":"Professor,Biochemistry","displayName":"Ronald Davis","lastName":"Davis"},{"researchInterest":"My laboratory focuses on understanding the transcriptional processes that govern the transformation of normal mammalian cells to neoplastic state.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zijie_Sun","appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Zijie","primaryAppointment":"Associate Professor,Urology","displayName":"Zijie Sun","lastName":"Sun"},{"researchInterest":"We study the molecular events that give rise to the sensation of touch and temperature in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels.  We also collaborate with Pruitt's group in Mechanical Engineering to develop and fabricate novel devices for the study of sensory transduction.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3813&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Miriam_Goodman","appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Miriam","primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","displayName":"Miriam B. Goodman","lastName":"Goodman"},{"researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Gerald","primaryAppointment":"Professor,Pathology","displayName":"Gerald Crabtree","lastName":"Crabtree"},{"researchInterest":"Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4159&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Margaret_Fuller","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Margaret","primaryAppointment":"Professor,Developmental Biology","displayName":"Margaret T. Fuller","lastName":"Fuller"},{"researchInterest":"Mark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics.  Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4409&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Kay","appointments":[{"appointment":"Professor,Pediatrics - Human Gene Therapy"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Pediatrics - Human Gene Therapy","displayName":"Mark A. Kay, M.D., Ph.D.","lastName":"Kay"},{"researchInterest":"We study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4308&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Roger_Kornberg","appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Roger","primaryAppointment":"Professor,Structural Biology","displayName":"Roger Kornberg","lastName":"Kornberg"},{"researchInterest":"The biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4459&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Karla_Kirkegaard","appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Karla","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Karla Kirkegaard","lastName":"Kirkegaard"}]}