{"result":[{"researchInterest":"Neuronal death after cerebral ischemia and neural injury using transgenic strategy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4423&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Pak_Chan","appointments":[{"appointment":"Professor,Neurosurgery"}],"clinicalFocus":[],"firstName":"Pak","primaryAppointment":"Professor,Neurosurgery","displayName":"Pak H. Chan","lastName":"Chan"},{"researchInterest":"Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6012&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anne_Brunet","appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Anne","primaryAppointment":"Assistant Professor,Genetics","displayName":"Anne Brunet","lastName":"Brunet"},{"researchInterest":"The cellular and molecular basis for brain cell injury in stroke is our focus.  Astrocytes and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles.  We study gene therapy with heat shock proteins, changes in mitochondrial function, oxidative stress and inflammation during ischemia. We also model cell death pathways and the effects of Hsp70.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4657&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Rona_Giffard","appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Rona","primaryAppointment":"Professor,Anesthesia","displayName":"Rona Giffard","lastName":"Giffard"},{"researchInterest":"My research interests extend from hypothesis-driven studies in biochemistry and cell biology to discovery-driven interests in proteomics and systems biology to clinical treatment of acute lymphoblastic leukemia of children, and pediatric palliative care.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3801&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Harvey_Cohen","appointments":[{"appointment":"Professor,Pediatrics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Hematology, Pediatric"},{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Oncology (Cancer), Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"firstName":"Harvey","primaryAppointment":"Professor,Pediatrics","displayName":"Harvey Cohen","lastName":"Cohen"},{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6114&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Sapolsky","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor,Neurosurgery"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Robert Sapolsky","lastName":"Sapolsky"},{"researchInterest":"Dr. Dodd is involved in clinical trials using endovascular coils that have a fiber coating that help heal aneurysms of the neck and can prevent an aneurysm from reforming. He uses minimally invasive endoscopic techniques to treat brain tumors.\r\n\r\nDodd's research interests are in cerebral blood vessel reactivity and stroke.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6790&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Dodd","appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurosurgery"},{"appointment":"Assistant Professor - Med Center Line,Radiology"}],"clinicalFocus":[{"focus":"Interventional Neuroradiology"},{"focus":"Neurosurgery"}],"firstName":"Robert","primaryAppointment":"Assistant Professor - Med Center Line,Neurosurgery","displayName":"Robert Dodd","lastName":"Dodd"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9626&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jian_Luo","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Jian","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Jian Luo","lastName":"Luo"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13745&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leslie_Lee","appointments":[{"appointment":"Clinical Assistant Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Leslie","primaryAppointment":"Clinical Assistant Professor,Neurology & Neurological Sciences","displayName":"Leslie Lee","lastName":"Lee"},{"researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Leonore","primaryAppointment":"Professor (Research),Genetics","displayName":"Leonore A. Herzenberg","lastName":"Herzenberg"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"},{"researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Theo_Palmer","appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Theo","primaryAppointment":"Associate Professor,Neurosurgery","displayName":"Theo Palmer","lastName":"Palmer"},{"researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5928&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_McConnell","appointments":[{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Susan","primaryAppointment":"Member,Bio-X","displayName":"Susan McConnell","lastName":"McConnell"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease. Pharmacogenetics of mood disorders and nicotine addiction.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Greer_Murphy","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Neurosciences"}],"clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"}],"firstName":"Greer","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Neurosciences","displayName":"Greer Murphy M.D., Ph.D.","lastName":"Murphy"},{"researchInterest":"Our laboratory studies the basic molecular mechanisms of muscle stem cell activation, the effects of aging on skeletal muscle, and gene therapy for hereditary muscle diseases.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4063&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Rando","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"Thomas Rando","lastName":"Rando"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9630&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Olzmann","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"James Olzmann","lastName":"Olzmann"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Nicholas_Denko","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Nicholas","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Biology","displayName":"Nicholas Denko","lastName":"Denko"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7584&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Alexis_Davis","appointments":[{"appointment":"Instructor,Pediatrics - Neonatology"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"}],"firstName":"Alexis","primaryAppointment":"Instructor,Pediatrics - Neonatology","displayName":"Alexis Davis","lastName":"Davis"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10387&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Young Min_Chung","appointments":[{"appointment":"Postdoctoral Research fellow, Obstetrics & Gynecology"}],"clinicalFocus":[],"firstName":"Young Min","primaryAppointment":"Postdoctoral Research fellow, Obstetrics & Gynecology","displayName":"Young Min Chung","lastName":"Chung"},{"researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Irving_Weissman","appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Irving","primaryAppointment":"Professor,Pathology - Stem Cell Institute","displayName":"Irving Weissman","lastName":"Weissman"},{"researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Cleary","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"},{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Professor,Pathology","displayName":"Michael Cleary","lastName":"Cleary"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14916&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Thomas_Davidson","appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Postdoctoral Research fellow, Bioengineering","displayName":"Tom Davidson","lastName":"Davidson"},{"researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Clarke","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Michael","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Michael F. Clarke, M.D.","lastName":"Clarke"}]}