{"result":[{"researchInterest":"Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease. Pharmacogenetics of mood disorders and nicotine addiction.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Greer_Murphy","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Neurosciences"}],"clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"}],"firstName":"Greer","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Neurosciences","displayName":"Greer Murphy M.D., Ph.D.","lastName":"Murphy"},{"researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Edgar_Engleman","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"firstName":"Edgar","primaryAppointment":"Professor,Pathology","displayName":"Edgar Engleman","lastName":"Engleman"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9626&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jian_Luo","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Jian","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Jian Luo","lastName":"Luo"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10140&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Eva_Czirr","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Eva","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Eva Czirr","lastName":"Czirr"},{"researchInterest":"We study cellular and molecular mechanisms of immune-mediated injury in central nervous system (CNS) tissues  that are altered in multiple sclerosis (MS). Tissues of patients and of animals with experimental allergic encephalomyelitis are analyzed using histology and immunohistochemistry.  We currently are studying the cross-recognition of neurons by antibodies against myelin proteolipid protein epitopes.  Similar cross-recognition may link anti-myelin immunity with neurodegeneration in MS.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4269&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Raymond_Sobel","appointments":[{"appointment":"Professor,Pathology"}],"clinicalFocus":[],"firstName":"Raymond","primaryAppointment":"Professor,Pathology","displayName":"Raymond A. Sobel, M.D.","lastName":"Sobel"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9654&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Zhiguo_Chen","appointments":[{"appointment":"Postdoctoral Research fellow, Neurosurgery"}],"clinicalFocus":[],"firstName":"Zhiguo","primaryAppointment":"Postdoctoral Research fellow, Neurosurgery","displayName":"Zhiguo Chen","lastName":"Chen"},{"researchInterest":"Our laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis.  We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab.  We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids.  We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3784&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Lawrence_Steinman","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor,Pediatrics"},{"appointment":"Professor (By courtesy),Genetics"}],"clinicalFocus":[{"focus":"Neurology"},{"focus":"Neurology, Pediatric"},{"focus":"Multiple Sclerosis, Myasthenia Gravis, Immune Disorders"}],"firstName":"Lawrence","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"Lawrence Steinman","lastName":"Steinman"},{"researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Frank_Longo","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"firstName":"Frank","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"Frank M. Longo, M.D., Ph.D.","lastName":"Longo"},{"researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have idintified a gene (GRAIL) that seems to control T cell anergy and are defining the regulatory T cell core transcriptome.  Additional studies are on the mechanism of effect of anti-CD3 antibodies in therapy of T1D.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","href":"http://med.stanford.edu/profiles/C_Fathman","appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"firstName":"C","primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","displayName":"C. Garrison Fathman","lastName":"Fathman"},{"researchInterest":"Our lab focuses on how inflammatory responses after brain injury affect neurological recovery. We utilize translational approaches to understand molecular mechanisms underlying functional recovery.  Molecular events are modified in mice using either transgenic models or novel small molecule compounds, and then we evaluate the effects on functional recovery as well as on cellular and molecular responses.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6463&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Marion_Buckwalter","appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Member,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Marion","primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","displayName":"Marion S. Buckwalter","lastName":"Buckwalter"},{"researchInterest":"My laboratory has two major research interests.  First, to define cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies.  Second, to determine how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants, with a particular focus on anti-viral vaccines.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4439&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_Lewis","appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"firstName":"David","primaryAppointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology","displayName":"David B. Lewis","lastName":"Lewis"},{"researchInterest":"Our research focuses on understanding disease mechanisms of stroke injury and neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS) as they relate to the COX-2-prostaglandin pathways.  We are identifying prostaglandin receptor pathways that are involved in these disease models, and our objective is to identify which receptors will be translationally relevant in human neurological disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7903&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Katrin_Andreasson","appointments":[{"appointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"}],"firstName":"Katrin","primaryAppointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences","displayName":"Katrin Andreasson","lastName":"Andreasson"},{"researchInterest":"Our lab studies the molecular mechanisms of and develops therapies to treat autoimmune and rheumatic diseases, with a focus on rheumatoid arthritis, multiple sclerosis, and osteoarthritis. \r\n\r\nThe overriding objectives of our laboratory are:\r\n\r\n1. To investigate the mechanisms underlying autoimmune diseases.\r\n\r\n2. To develop diagnostics and therapeutics for autoimmune diseases.\r\n\r\n3. To investigate the role of inflammation in osteoarthritis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4730&type=small&showNoImage","href":"http://med.stanford.edu/profiles/William_Robinson","appointments":[{"appointment":"Assistant Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"firstName":"William","primaryAppointment":"Assistant Professor,Medicine - Immunology & Rheumatology","displayName":"William Robinson","lastName":"Robinson"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4556&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Paul_Hwang","appointments":[{"appointment":"Clinical Assistant Professor,Pediatrics - Neonatology"}],"clinicalFocus":[],"firstName":"Paul","primaryAppointment":"Clinical Assistant Professor,Pediatrics - Neonatology","displayName":"Paul Hwang","lastName":"Hwang"},{"researchInterest":"Development and nanoscale assembly of carbon nanotubes and related nanomaterials for electronic and energy applications.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8779&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Melburne_LeMieux","appointments":[{"appointment":"Postdoctoral Research fellow, Chemical Engineering"}],"clinicalFocus":[],"firstName":"Melburne","primaryAppointment":"Postdoctoral Research fellow, Chemical Engineering","displayName":"Melbs LeMieux","lastName":"LeMieux"},{"researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Shoshana_Levy","appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Shoshana","primaryAppointment":"Professor (Research),Medicine - Oncology","displayName":"Shoshana Levy","lastName":"Levy"},{"researchInterest":"Molecular mechanisms of lymphocyte recognition and differentiation; molecular genetics and expression of T-cell receptor genes.  Dynamics and functionality of specific T cell populations in human cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4282&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Davis","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Mark M. Davis","lastName":"Davis"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"Our interests include: \r\n1) The physiology and significance of lymphocyte homing in local and systemic immunity; \r\n2) biochemical and genetic studies of molecules that direct leukocyte recruitment; \r\n3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; \r\n4) vascular differentiation in normal and pathologic inflammatory states; \r\n5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4498&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Eugene_Butcher","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Eugene","primaryAppointment":"Professor,Pathology","displayName":"Eugene Butcher","lastName":"Butcher"},{"researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Leonore","primaryAppointment":"Professor (Research),Genetics","displayName":"Leonore A. Herzenberg","lastName":"Herzenberg"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7015&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Marion_Smith","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Marion","primaryAppointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences","displayName":"Marion Smith","lastName":"Smith"},{"researchInterest":"My interests lie on the glia reactivity and proliferation with aging after focal ischemic injury. Some aims are proposed:\r\n* Role of astrocyte and microglia impairment in focal ischemia;\r\n\r\nand\r\n\r\n* Gene therapy for stroke with superoxide dismutase 2.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11191&type=small&showNoImage","href":"http://med.stanford.edu/profiles/George_Barreto","appointments":[{"appointment":"Postdoctoral Research fellow, Anesthesia"}],"clinicalFocus":[],"firstName":"George","primaryAppointment":"Postdoctoral Research fellow, Anesthesia","displayName":"George Barreto","lastName":"Barreto"},{"researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Theo_Palmer","appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Theo","primaryAppointment":"Associate Professor,Neurosurgery","displayName":"Theo Palmer","lastName":"Palmer"},{"researchInterest":"We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in \"a vacuum\" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4036&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Christopher_Contag","appointments":[{"appointment":"Associate Professor,Pediatrics - Neonatology"},{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Associate Professor (By courtesy),Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Christopher","primaryAppointment":"Associate Professor,Pediatrics - Neonatology","displayName":"Christopher H. Contag","lastName":"Contag"}]}