{"result":[{"researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Matthew_Scott","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Matthew","primaryAppointment":"Professor,Developmental Biology","displayName":"Matthew Scott","lastName":"Scott"},{"researchInterest":"Genetic and cell biological analyses of signals controlling cell polarity and cell proliferation and differentiation.  Frizzled signaling and cytoskeletal organization.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4410&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jeffrey_Axelrod","appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jeffrey","primaryAppointment":"Associate Professor,Pathology","displayName":"Jeffrey Axelrod","lastName":"Axelrod"},{"researchInterest":"We are studying how neural circuits are assembled during development, and how they contribute to sensory perception.  We are addressing these questions at different levels from molecular, cellular, circuit to animal behavior.  We are primarily using Drosophila as a model organism for our studies.  Most recently, we are also developing novel genetic tools in the mouse to extend our studies to the mammalian brain.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6229&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Liqun_Luo","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor (By courtesy),Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Liqun","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Liqun Luo","lastName":"Luo"},{"researchInterest":"Genetic and molecular basis of respiratory system  development, maintenance, and disease in Drosophila, mouse, and human","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Mark_Krasnow","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Biochemistry","displayName":"Mark Krasnow","lastName":"Krasnow"},{"researchInterest":"We are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer\u0092s and Parkinson\u0092s diseases. We are using both Drosophila and mammalian models to address these fundamental questions.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3976&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Bingwei_Lu","appointments":[{"appointment":"Assistant Professor,Pathology"}],"clinicalFocus":[],"firstName":"Bingwei","primaryAppointment":"Assistant Professor,Pathology","displayName":"Bingwei Lu","lastName":"Lu"},{"researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Roeland_Nusse","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Roeland","primaryAppointment":"Professor,Developmental Biology","displayName":"Roeland Nusse","lastName":"Nusse"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6206&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Bruce_Baker","appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Bruce","primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","displayName":"Bruce Baker","lastName":"Baker"},{"researchInterest":"We study innate immunity and microbial pathogenesis. We have been studying models for a variety of bacterial infections including:  Listeria, Mycobacteria, Salmonella and Streptococcus as well as some fungi, parasites and viruses.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4580&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_Schneider","appointments":[{"appointment":"Associate Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Associate Professor,Microbiology & Immunology","displayName":"David Schneider","lastName":"Schneider"},{"researchInterest":"Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4159&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Margaret_Fuller","appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Margaret","primaryAppointment":"Professor,Developmental Biology","displayName":"Margaret T. Fuller","lastName":"Fuller"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8872&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Rory_Sayres","appointments":[{"appointment":"Postdoctoral Research fellow, Psychology"}],"clinicalFocus":[],"firstName":"Rory","primaryAppointment":"Postdoctoral Research fellow, Psychology","displayName":"Rory Sayres","lastName":"Sayres"},{"researchInterest":"The development and organization of visual cortex.  The study of the brain pathways essential for reading development.  Diffusion tensor imaging, functional magnetic resonance imaging and computational modeling of visual perception and brain processes.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7651&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Brian_Wandell","appointments":[{"appointment":"Professor,Psychology"},{"appointment":"Professor (By courtesy),Electrical Engineering"},{"appointment":"Professor (By courtesy),Radiology"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Brian","primaryAppointment":"Professor,Psychology","displayName":"Brian A. Wandell","lastName":"Wandell"},{"researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ben_Barres","appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"clinicalFocus":[],"firstName":"Ben","primaryAppointment":"Professor,Neurobiology","displayName":"Ben Barres","lastName":"Barres"},{"researchInterest":"Development and regeneration of the visual system","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9622&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Andrew_Huberman","appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"clinicalFocus":[],"firstName":"Andrew","primaryAppointment":"Postdoctoral Research fellow, Neurobiology","displayName":"Andrew D. Huberman","lastName":"Huberman"},{"researchInterest":"The goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8146&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Carla_Shatz","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Carla","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Carla Shatz","lastName":"Shatz"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10397&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Rothenberg","appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Postdoctoral Medical fellow, Medicine","displayName":"Michael Rothenberg","lastName":"Rothenberg"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9160&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stephan_Gehrke","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Stephan","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Stephan Gehrke","lastName":"Gehrke"},{"researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Craig_Garner","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Craig","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Craig C. Garner","lastName":"Garner"},{"researchInterest":"Tobin is a Senior Research Scholar in the Program for Genomics, Ethics, and Society at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983, where she established her independent research l","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6945&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Sara_Tobin","appointments":[{"appointment":"Member,Cancer Center"},{"appointment":"Sr Research Scholar (PI Waiver),Center for Biomedical Ethics"}],"clinicalFocus":[],"firstName":"Sara","primaryAppointment":"Member,Cancer Center","displayName":"Sara L. (Sally) Tobin","lastName":"Tobin"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9649&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_Tran","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"David Tran","lastName":"Tran"},{"researchInterest":"We study how the neural circuitry of the vertebrate retina encodes visual scenes. We use a combination of experimental and theoretical methods, including multielectrode extracellular array recording, intracellular recording, two-photon laser scanning imaging, and computational modelling.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6027&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stephen_Baccus","appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Stephen","primaryAppointment":"Assistant Professor,Neurobiology","displayName":"Stephen A. Baccus","lastName":"Baccus"},{"researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Chen","appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Assistant Professor (By courtesy),Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Assistant Professor,Chemical and Systems Biology","displayName":"James K. Chen","lastName":"Chen"},{"researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Frank_Longo","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"firstName":"Frank","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"Frank M. Longo, M.D., Ph.D.","lastName":"Longo"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10462&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ilana_Witten","appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"clinicalFocus":[],"firstName":"Ilana","primaryAppointment":"Postdoctoral Research fellow, Bioengineering","displayName":"Ilana Witten","lastName":"Witten"},{"researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5928&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Susan_McConnell","appointments":[{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Susan","primaryAppointment":"Member,Bio-X","displayName":"Susan McConnell","lastName":"McConnell"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8816&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anand_Chandrasekaran","appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"clinicalFocus":[],"firstName":"Anand","primaryAppointment":"Postdoctoral Research fellow, Bioengineering","displayName":"Anand Chandrasekaran","lastName":"Chandrasekaran"}]}