{"result":[{"lastName":"Arvin","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4188&type=small&showNoImage","displayName":"Ann M. Arvin","firstName":"Ann","href":"http://med.stanford.edu/profiles/Ann_Arvin","researchInterest":"Our laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells  in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections."},{"lastName":"Lewis","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4439&type=small&showNoImage","displayName":"David B. Lewis","firstName":"David","href":"http://med.stanford.edu/profiles/David_Lewis","researchInterest":"My laboratory has two major research interests.  First, to define cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies.  Second, to determine how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants, with a particular focus on anti-viral vaccines."},{"lastName":"Prober","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4095&type=small&showNoImage","displayName":"Charles G. Prober","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Prober","researchInterest":"My area of research interest is focused on the epidemiology, pathophysiology, prevention, and treatment of infections in children. Much of my research has focused on viral infections, especially those caused by herpes simplex virus (HSV). I have conducted a number of studies concerned with the epidemiology of HSV-2 infections in pregnant women, their partners, and neonates. Recently, I have extended these epidemiologic studies to adolescents."},{"lastName":"Engleman","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","displayName":"Edgar Engleman","firstName":"Edgar","href":"http://med.stanford.edu/profiles/Edgar_Engleman","researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease."},{"lastName":"Greenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3791&type=small&showNoImage","displayName":"Harry B Greenberg","firstName":"Harry","href":"http://med.stanford.edu/profiles/Harry_Greenberg","researchInterest":"Molecular mechanisms of pathogenesis; determinants of protective immunity; host range and tissue tropism in liver and GI tract pathogenic viruses and studies of vaccines in people."},{"lastName":"Chen","clinicalFocus":[{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Instructor,Pediatrics - Infectious Diseases"}],"primaryAppointment":"Instructor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7992&type=small&showNoImage","displayName":"Sharon F. Chen","firstName":"Sharon","href":"http://med.stanford.edu/profiles/Sharon_Chen","researchInterest":"My research interest is focused on Herpes virus pathogenesis and the host immune response to these viral infections. To characterize these interactions, we use flow-cytometry based immunology assays, culture-based assays, molecular techniques and tissue histology. My current study investigates anti-viral immunity to CMV in lung transplant patients to characterize the kinetics of CMV-specific T-cell reconstitution and to test its ability to predict CMV infection and allograft rejection."},{"lastName":"Maldonado","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor (By courtesy),Health Research & Policy"}],"primaryAppointment":"Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4663&type=small&showNoImage","displayName":"Yvonne Maldonado","firstName":"Yvonne","href":"http://med.stanford.edu/profiles/Yvonne_Maldonado","researchInterest":"My research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio.  I also work in development of methods to prevent breastfeeding transmission of HIV in Africa."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus (Active) Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","displayName":"Leonard Herzenberg","firstName":"Leonard","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC)."},{"lastName":"Patterson","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Medicine"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3975&type=small&showNoImage","displayName":"Bruce Patterson","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Patterson","researchInterest":"Our laboratory focuses on host-viral interactions in the sexual and mother-to-child transmission of HIV-1. We developed human organotypic models to closely mimic in vivo infection. Our recent work has focused on developing immune-based and small molecule inhibitors of HIV-1 transmission."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","displayName":"Leonore A. Herzenberg","firstName":"Leonore","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays."},{"lastName":"Bass","clinicalFocus":[{"focus":"Gastroenterology/Nutrition/Hepatology, Pediatric"},{"focus":"Pediatric Gastroenterology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Gastroenterology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Gastroenterology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4017&type=small&showNoImage","displayName":"Dorsey Bass","firstName":"Dorsey","href":"http://med.stanford.edu/profiles/Dorsey_Bass","researchInterest":"Our laboratory is interested in the pathophysiology, immunology, and epidemiology of viral gastroenteritis."},{"lastName":"Gans","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pediatrics - Infectious Diseases"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4053&type=small&showNoImage","displayName":"Hayley Gans","firstName":"Hayley","href":"http://med.stanford.edu/profiles/Hayley_Gans","researchInterest":"The focus of my laboratory is the immune response to viral vaccines evaluating the ontogeny of responses in infants and limitations in immunocompromised hosts.  We have studied responses to an early two-dose measles immunization, one versus 2 doses of varicella immunization, and polio vaccine in preterm versus term infants. Other active areas of research include measles and varicella immunity in HIV infected individuals, and transplant recipients."},{"lastName":"Varghese","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10207&type=small&showNoImage","displayName":"Vici Varghese","firstName":"Vici","href":"http://med.stanford.edu/profiles/Vici_Varghese","researchInterest":""},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Liver Transplantation"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://med.stanford.edu/profiles/Clark_Bonham","researchInterest":""},{"lastName":"Mocarski","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4146&type=small&showNoImage","displayName":"Edward Mocarski","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Mocarski","researchInterest":"Research focusses on one of the human herpesviruses: cytomegalovirus (CMV). This virus is a major medical problem in immunocompromised individuals. The virus is very large, carrying over 200 genes. We have characterized functions involved in viral growth (regulation of gene expression, replication, genome packaging) and pathogenesis (tissue tropism, latency). Molecular genetic and biochemical approaches have been employed to dissect these functions."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Butcher","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4498&type=small&showNoImage","displayName":"Eugene Butcher","firstName":"Eugene","href":"http://med.stanford.edu/profiles/Eugene_Butcher","researchInterest":"Our interests include: \r\n1) The physiology and significance of lymphocyte homing in local and systemic immunity; \r\n2) biochemical and genetic studies of molecules that direct leukocyte recruitment; \r\n3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; \r\n4) vascular differentiation in normal and pathologic inflammatory states; \r\n5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs."},{"lastName":"Lee","clinicalFocus":[{"focus":"Hematology"},{"focus":"Leukemia - Hematology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4564&type=small&showNoImage","displayName":"Peter P. Lee","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Lee","researchInterest":"Understanding the biology of cancer-T cell interactions."},{"lastName":"Holodniy","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Infectious Diseases"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4021&type=small&showNoImage","displayName":"Mark Holodniy","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Holodniy","researchInterest":"My research program is currently focused in three areas: 1) translational research (HCV/HIV viral evolution and antiviral resistance prevalence and development), 2) HIV/HCV clinical trials (diagnostic assay/medical device, antiretrovirals, ARVs and immunomodulators), and 3) health services research focusing on cost effectiveness of HIV antibody and ARV resistance testing and ARV utilization and clincal outcome."},{"lastName":"Fathman","clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","displayName":"C. Garrison Fathman","firstName":"C","href":"http://med.stanford.edu/profiles/C_Fathman","researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have idintified a gene (GRAIL) that seems to control T cell anergy and are defining the regulatory T cell core transcriptome.  Additional studies are on the mechanism of effect of anti-CD3 antibodies in therapy of T1D."},{"lastName":"Katzenstein","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Infectious Diseases"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4325&type=small&showNoImage","displayName":"David Katzenstein","firstName":"David","href":"http://med.stanford.edu/profiles/David_Katzenstein","researchInterest":"Treatment and evaluation of HIV infectionin the United States and Europe through the AIDS Clinical Trials Group (ACTG). International HIV pathogenesis work includes studies in Zimbabwe, South Africa, and India where we are particularly interested in the pandemic of subtype C HIV-1, TB and other co-infections. The lab currently is focused on drug resistance, envelope tropism and the pathogenesis of HIV."},{"lastName":"Pizzo","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Dean of the School of Medicine,Stanford University School of Medicine"},{"appointment":"Professor,Pediatrics"},{"appointment":"The Carl and Elizabeth Naumann Dean,Stanford University School of Medicine"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Dean of the School of Medicine,Stanford University School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3843&type=small&showNoImage","displayName":"Philip A. Pizzo, M.D.","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Pizzo","researchInterest":""},{"lastName":"Foung","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4155&type=small&showNoImage","displayName":"Steven Foung","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Foung","researchInterest":"Our research focus is on the early events of hepatitis C virus infection- virus attachment and entry into susceptible cells. The approach is through the generation and functional studies of human monoclonal antibodies (HMAbs) to the virus envelope proteins with an emphasis on antibodies to conformational epitopes."},{"lastName":"Mellins","clinicalFocus":[{"focus":"Pediatric Rheumatology"},{"focus":"Rheumatology, Pediatric"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Human Gene Therapy"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Human Gene Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5952&type=small&showNoImage","displayName":"Elizabeth Mellins","firstName":"Elizabeth","href":"http://med.stanford.edu/profiles/Elizabeth_Mellins","researchInterest":"Molecular mechanisms and intracellular pathways of antigen processing and presentation; structure/function of HLA-DR,-DM, -DO; HLA allele association with disease; pathogen evasion of the class II pathway."}]}