{"result":[{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12553&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Valeria_Vasquez","appointments":[{"appointment":"Postdoctoral Research fellow, Mechanical Engineering"}],"clinicalFocus":[],"firstName":"Valeria","primaryAppointment":"Postdoctoral Research fellow, Mechanical Engineering","displayName":"Valeria Vasquez","lastName":"Vasquez"},{"researchInterest":"Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4433&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Pehr_Harbury","appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Pehr","primaryAppointment":"Associate Professor,Biochemistry","displayName":"Pehr Harbury","lastName":"Harbury"},{"researchInterest":"Is it possible to understand the molecular structure and function of proteins and nucleic acids in enough detail to make accurate predictions about structure and function? We are mounting a two-pronged attack on this problem using both molecular dynamics simulation and molecular modeling.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Michael_Levitt","appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Michael","primaryAppointment":"Professor,Structural Biology","displayName":"Michael Levitt","lastName":"Levitt"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8050&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Steven_Boxer","appointments":[{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Steven","primaryAppointment":"Member,Bio-X","displayName":"Steven Boxer","lastName":"Boxer"},{"researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","href":"http://med.stanford.edu/profiles/David_McKay","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","displayName":"David B. McKay","lastName":"McKay"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8768&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Shelley_Elvington","appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Shelley","primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","displayName":"Shelley Elvington","lastName":"Elvington"},{"researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Oleg_Jardetzky","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"clinicalFocus":[],"firstName":"Oleg","primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","displayName":"Oleg Jardetzky","lastName":"Jardetzky"},{"researchInterest":"I am currently working on the development of the activity based probes for lysosomal and matrix proteases and their application for in vivo imaging.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9804&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jiyoun_Lee","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Jiyoun","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Jiyoun Lee","lastName":"Lee"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10008&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Stephen_Kaiser","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Stephen","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"Stephen Kaiser","lastName":"Kaiser"},{"researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","href":"http://med.stanford.edu/profiles/William_Weis","appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"William","primaryAppointment":"Professor,Structural Biology","displayName":"William Weis","lastName":"Weis"},{"researchInterest":"I closed my laboratory when I retired in 1998.  I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation,  and to write reviews.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6816&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Robert_Baldwin","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","displayName":"Robert Baldwin","lastName":"Baldwin"},{"researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Chris_Garcia","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Chris","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Chris Garcia","lastName":"Garcia"},{"researchInterest":"Molecular theories of anesthesia. My emphasis is on the molecular interactions of inhalational anesthetics and alcohol. I perform computational chemistry simulations on how these molecules bind to putative receptor sites. I am also interested in modeling receptor proteins in which chimeras cause loss or enhancement of anesthetic sensitivity.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4617&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Trudell","appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Professor,Anesthesia","displayName":"James Trudell","lastName":"Trudell"},{"researchInterest":"Ion channels and signal transduction;  patch clamp and fluorometric analysis; cell and molecular biology; cystic fibrosis gene therapy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4500&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Phyllis_Gardner","appointments":[{"appointment":"Professor,Medicine - Clinical Pharmacology"}],"clinicalFocus":[{"focus":"Clinical Pharmacology"}],"firstName":"Phyllis","primaryAppointment":"Professor,Medicine - Clinical Pharmacology","displayName":"Phyllis Gardner","lastName":"Gardner"},{"researchInterest":"Dr. Amy Eastwood\u0092s career has not just bloomed\u0097it has rocketed.  From her takeoff in high school where her chemistry teacher inspired her to pursue a career in science, Dr. Eastwood obtained her Ph.D. at Caltech University, which in turn drew her interest to look at her research on ion channels in a more natural environment.  \r\n\r\nHouston, we have found C. elegans. Dr. Eastwood came to Stanford University in late 2008 and now, with the Stanford University\u0092s Dean Fellowship and a NIH NRSA Fellows","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10621&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Amy_Eastwood","appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Amy","primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","displayName":"Amy L Eastwood","lastName":"Eastwood"},{"researchInterest":"My lab has two main goals: to understand mitotic regulation and to understand the systems-level logic of simple signaling circuits.  We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study.  We also carry out single-cell fluorescence imaging studies on mammalian cell lines.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4656&type=small&showNoImage","href":"http://med.stanford.edu/profiles/James_Ferrell","appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Professor,Chemical and Systems Biology","displayName":"James Ferrell","lastName":"Ferrell"},{"researchInterest":"Rhiju Das strives to predict how sequence codes for structure in proteins, nucleic acids, and heteropolymers whose folds have yet to be explored. The Das group uses new computational and experimental tools to tackle the de novo modeling of protein and RNA folds, the high-throughput structure mapping of riboswitches and random RNAs, and the design of self-knotting and self-crystallizing nucleic acids.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10421&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Rhiju_Das","appointments":[{"appointment":"Assistant Professor,Biochemistry"}],"clinicalFocus":[],"firstName":"Rhiju","primaryAppointment":"Assistant Professor,Biochemistry","displayName":"Rhiju Das","lastName":"Das"},{"researchInterest":"1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity; 4. Bioremediation.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4329&type=small&showNoImage","href":"http://med.stanford.edu/profiles/AC_Matin","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"AC","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"AC Matin","lastName":"Matin"},{"researchInterest":"Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells.  We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6227&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Ron_Kopito","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ron","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Ron Kopito","lastName":"Kopito"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9098&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Nam-Joon_Cho","appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"clinicalFocus":[],"firstName":"Nam-Joon","primaryAppointment":"Postdoctoral Research fellow, School of Medicine","displayName":"Nam-Joon Cho, Ph.D.","lastName":"Cho"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8633&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Jonathan_Lassila","appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"clinicalFocus":[],"firstName":"Jonathan","primaryAppointment":"Postdoctoral Research fellow, Biochemistry","displayName":"Jonathan Lassila","lastName":"Lassila"},{"researchInterest":"molecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4079&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Edward_Bertaccini","appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Edward","primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","displayName":"Edward Bertaccini","lastName":"Bertaccini"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9040&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Avraham_Samson","appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"clinicalFocus":[],"firstName":"Avraham","primaryAppointment":"Postdoctoral Research fellow, Structural Biology","displayName":"Avraham Samson","lastName":"Samson"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9637&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Soren_Rasmussen","appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Soren","primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","displayName":"Soren Rasmussen","lastName":"Rasmussen"},{"researchInterest":"Watching cells at work \r\nFocus: Transport / signaling across the plasma membrane (sugars, amino acids). \r\nTools: FRET-based nanosensors for metabolite imaging (with subcellular resolution) in living organisms using confocal fluorescence microscopy and HTS; Sensor optimization by computational design; RNAi to modify cellular functions.\r\nGoals: Identify unknown sugar effluxers from liver/plant cells; study regulatory networks. \r\nModel systems: liver, neuronal, plant cell cultures, Arabidopsis, yeast","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6305&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Wolf_Frommer","appointments":[{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Wolf","primaryAppointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)","displayName":"Wolf B. Frommer","lastName":"Frommer"}]}