{"result":[{"lastName":"Duque Afonso","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29334&type=small&showNoImage","displayName":"Atilio Jesus Duque-Afonso","firstName":"Atilio","href":"http://med.stanford.edu/profiles/Atilio_Duque Afonso","researchInterest":""},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Bachmann","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Pediatrics - Neonatal and Developmental Medicine"}],"primaryAppointment":"Basic Life Science Research Associate,Pediatrics - Neonatal and Developmental Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29151&type=small&showNoImage","displayName":"Michael H. Bachmann","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Bachmann","researchInterest":""},{"lastName":"Dalerba","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute"}],"primaryAppointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9693&type=small&showNoImage","displayName":"Piero Dalerba","firstName":"Piero","href":"http://med.stanford.edu/profiles/Piero_Dalerba","researchInterest":"Cancer Stem Cells, Colon Cancer, Breast Cancer"},{"lastName":"Medeiros","clinicalFocus":[{"focus":"Hematology"},{"focus":"Acute leukemia"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Hematology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7743&type=small&showNoImage","displayName":"Bruno Medeiros","firstName":"Bruno","href":"http://med.stanford.edu/profiles/Bruno_Medeiros","researchInterest":"My clinical activities combine the development of novel therapeutic modalities, translational research activities and epidemiological study of acute leukemia. My special focus is on the development of better, patient tailored therapies for young and elderly patients with acute leukemia."},{"lastName":"Adorno","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10402&type=small&showNoImage","displayName":"Maddalena Adorno","firstName":"Maddalena","href":"http://med.stanford.edu/profiles/Maddalena_Adorno","researchInterest":""},{"lastName":"Wen","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Chemical and Systems Biology"},{"appointment":"MS, School of Medicine"}],"primaryAppointment":"Ph.D., Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19757&type=small&showNoImage","displayName":"Susanna Wen","firstName":"Susanna","href":"http://med.stanford.edu/profiles/Susanna_Wen","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Arber","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Hematopathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","displayName":"Daniel A. Arber, M.D.","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Arber","researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors."},{"lastName":"Seita","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute"}],"primaryAppointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10040&type=small&showNoImage","displayName":"Jun Seita","firstName":"Jun","href":"http://med.stanford.edu/profiles/Jun_Seita","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."},{"lastName":"George","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3926&type=small&showNoImage","displayName":"Tracy I. George","firstName":"Tracy","href":"http://med.stanford.edu/profiles/Tracy_George","researchInterest":"My interest in translational hematopathology includes systemic mastocytosis and other myeloproliferative neoplasms, laboratory hematology, post-transplant and immunodeficiency-related lymphoproliferative disorders, and reactive lymphadenopathies. I am the pathologist on two clinical trials in treating aggressive types of systemic mastocytosis with an alternative small molecule inhibitor. I chair CAP's Hematology & Clinical Microscopy Resource Committee."},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Angelotti","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4339&type=small&showNoImage","displayName":"Timothy Angelotti MD, PhD","firstName":"Timothy","href":"http://med.stanford.edu/profiles/Timothy_Angelotti","researchInterest":"My research efforts are focused on investigating the pharmacological and physiological interface of the autonomic nervous system with effector organs. Utilizing molecular, cellular, and electrophysiological techniques, we are examining alpha2 adrenergic receptor function in cultured sympathetic neurons. Future research aims will be directed toward understanding neurotransmitter release in general."},{"lastName":"Gambhir","clinicalFocus":[{"focus":"Nuclear Medicine"},{"focus":"Radiology"},{"focus":"PET Scan"}],"appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Professor (By courtesy),Materials Science and Engineering - Engineering Materials Science"}],"primaryAppointment":"Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3971&type=small&showNoImage","displayName":"Sanjiv Sam Gambhir, MD, PhD","firstName":"Sanjiv","href":"http://med.stanford.edu/profiles/Sanjiv_Gambhir","researchInterest":"My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed.  Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology,  as well as in molecular therapeutics including gene therapy"},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Twist","clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Oncology (Cancer), Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Hematology & Oncology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Hematology & Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4366&type=small&showNoImage","displayName":"Clare J. Twist","firstName":"Clare","href":"http://med.stanford.edu/profiles/Clare_Twist","researchInterest":"My primary research interest is in the study and treatment of neuroblastoma. My clinical interests also include Wilms tumor, hepatoblastoma, post-transplant lymphoproliferative disorders, phase I therapies for hematologic malignancies, as well as  palliative and end of life care."},{"lastName":"Chaudhuri","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23056&type=small&showNoImage","displayName":"Aadel Chaudhuri","firstName":"Aadel","href":"http://med.stanford.edu/profiles/Aadel_Chaudhuri","researchInterest":""},{"lastName":"Gotlib","clinicalFocus":[{"focus":"Hematology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Hematology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4046&type=small&showNoImage","displayName":"Jason Gotlib","firstName":"Jason","href":"http://med.stanford.edu/profiles/Jason_Gotlib","researchInterest":"My research interests include phase I/II clinical trial evaluation of novel therapies for the following diseases:\r\n--Myelodysplastic syndromes (MDS)\r\n--Chronic myelogenous leukemia (CML)\r\n--Acute myelogenous leukemia (AML)\r\n--Myeloproliferative disorders (MPDs) including:\r\n    Hypereosinophilic syndrome\r\n    Systemic mastocytosis\r\n    BCR-ABL-negative MPDs"}]}