{"result":[{"lastName":"Cartwright","clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Inflammatory Bowel Diseases"}],"appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4183&type=small&showNoImage","displayName":"Chris Cartwright, MD","firstName":"Christine","href":"http://med.stanford.edu/profiles/Christine_Cartwright","researchInterest":"Molecular mechanisms of intestinal cell growth control; function and regulation of the Src family of tyrosine kinases in normal cells, and their deregulation in cancer cells."},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism.  Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy.  Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells.  We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."},{"lastName":"Mourrain","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24313&type=small&showNoImage","displayName":"Philippe Mourrain","firstName":"Philippe","href":"http://med.stanford.edu/profiles/Philippe_Mourrain","researchInterest":""},{"lastName":"Olivares","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18321&type=small&showNoImage","displayName":"Gonzalo Olivares","firstName":"Gonzalo","href":"http://med.stanford.edu/profiles/Gonzalo_Olivares","researchInterest":"Stem cells are unique in that can renew themselves through cell division or differentiate into a diverse range of specialized cell types.  I will study genes that functions to prevent the growth of tumors and regulates stem cell decisions. Understanding the molecular mechanisms that mediate the choice between self-renewal and differentiation in stem cells has important implications for many areas of biology, including ancer treatment, regenerative medicine and new cell-based therapies."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Chemistry Department"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","displayName":"James K. Chen","firstName":"James","href":"http://med.stanford.edu/profiles/James_Chen","researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development."},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during repair and regeneration after tissue injury."},{"lastName":"Yan","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Hematology"}],"primaryAppointment":"Instructor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13412&type=small&showNoImage","displayName":"Kelley Yan","firstName":"Kelley","href":"http://med.stanford.edu/profiles/Kelley_Yan","researchInterest":""},{"lastName":"Lowe","clinicalFocus":[{"focus":"Gastroenterology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4184&type=small&showNoImage","displayName":"Anson Lowe","firstName":"Anson","href":"http://med.stanford.edu/profiles/Anson_Lowe","researchInterest":"Pancreatic and esophageal cancers are common and deadly cancers of the gastrointestinal tract.  Our laboratory is currently focused on the characterization of  genes important in tumor development and growth.  Such genes will potentially serve as therapeutic targets.\r\n\r\nAn additional focus of the laboratory is the development of diagnostic assays for the early detection of pancreatic and esophageal disease."},{"lastName":"Yamazoe","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=16859&type=small&showNoImage","displayName":"Sayumi Yamazoe","firstName":"Sayumi","href":"http://med.stanford.edu/profiles/Sayumi_Yamazoe","researchInterest":""},{"lastName":"Rothenberg","clinicalFocus":[{"focus":"Gastroenterology"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Clinical Instructor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10397&type=small&showNoImage","displayName":"Michael Rothenberg","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Rothenberg","researchInterest":""},{"lastName":"Raymond","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4369&type=small&showNoImage","displayName":"Jennifer L. Raymond","firstName":"Jennifer","href":"http://med.stanford.edu/profiles/Jennifer_Raymond","researchInterest":"We study the neural mechanisms of learning, using a combination of behavioral, neurophysiological, and computational approaches.  The model system we use is a form of cerebellum-dependent learning that regulates eye movements."},{"lastName":"Doncic","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11473&type=small&showNoImage","displayName":"Andreas Doncic","firstName":"Andreas","href":"http://med.stanford.edu/profiles/Andreas_Doncic","researchInterest":""},{"lastName":"Palanker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Ophthalmology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Ophthalmology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4579&type=small&showNoImage","displayName":"Daniel Palanker","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Palanker","researchInterest":"Interactions of electric field and light with biological cells and tissues and their applications to diagnostics, therapeutics and prosthetics, primarily in ophthalmology.\r\n\r\nSpecific fields of interest include:\r\nMinimally-invasive optical therapeutics;\r\nElectronic retinal prosthesis; \r\nMicrosurgical and cell-surgical technologies; \r\nOptical imaging and spectroscopy; \r\nElectronic control of cells and tissues;"},{"lastName":"Zhao","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Stem Cell"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18651&type=small&showNoImage","displayName":"Ludan \"Dani\" Zhao","firstName":"Ludan","href":"http://med.stanford.edu/profiles/Ludan_Zhao","researchInterest":""},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20934&type=small&showNoImage","displayName":"Lu Chen","firstName":"Lu","href":"http://med.stanford.edu/profiles/Lu_Chen","researchInterest":"What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation."},{"lastName":"Baccus","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6027&type=small&showNoImage","displayName":"Stephen A. Baccus","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Baccus","researchInterest":"We study how the neural circuitry of the vertebrate retina encodes visual information and performs computations. To control and measure the retinal circuit, we present visual images while performing simultaneous two-photon imaging and multielectrode recording. We perturb the circuit as it operates using simultaneous intracellular current injection and multielectrode recording, and use the resulting large data sets to construct models of retinal computation."},{"lastName":"Fisher","clinicalFocus":[],"appointments":[{"appointment":"Professor,Natural Sciences Cluster - Applied Physics"},{"appointment":"Professor (By courtesy),Bioengineering"}],"primaryAppointment":"Professor,Natural Sciences Cluster - Applied Physics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8594&type=small&showNoImage","displayName":"Daniel Fisher","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Fisher","researchInterest":""},{"lastName":"Sylvester","clinicalFocus":[{"focus":"Surgery, Pediatric"},{"focus":"Pediatric Surgery"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor - Med Center Line,Pediatrics"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3827&type=small&showNoImage","displayName":"Karl Sylvester","firstName":"Karl","href":"http://med.stanford.edu/profiles/Karl_Sylvester","researchInterest":"Current research interests include mesenchymal stem cell biology, clonal isolation of mesenchymal progenitors, signaling pathways for maintenance of potency and committment to differentiation.\r\n\r\nAdditional areas of ongoing study are the mechanisms of liver regeneration.  Interests include local and humoral cellular components of liver repair and regrowth; and the requisite cellular signaling mechanisms of liver stem cell biology."},{"lastName":"Nicolosi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36099&type=small&showNoImage","displayName":"Piper Nicolosi","firstName":"Piper","href":"http://med.stanford.edu/profiles/Piper_Nicolosi","researchInterest":""}]}