{"result":[{"lastName":"Childers","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18881&type=small&showNoImage","displayName":"W. Seth Childers","firstName":"William","href":"http://med.stanford.edu/profiles/William_Childers","researchInterest":""},{"lastName":"Layton","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20987&type=small&showNoImage","displayName":"Curtis Layton","firstName":"Curtis","href":"http://med.stanford.edu/profiles/Curtis_Layton","researchInterest":""},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Computer Science"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Levitt","researchInterest":"having pioneered, we (a) predict folding of a polypeptide and RNA chains into a unique native-structure, we (b) model protein structure using the well-established paradigms that similar protein sequences imply similar three-dimensional structures, and (c) we are focusing on mesoscale modeling of large macromolecular complexes such as RNA polymerase and the mammalian chaperonin."},{"lastName":"Nag","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23884&type=small&showNoImage","displayName":"Suman Nag","firstName":"Suman","href":"http://med.stanford.edu/profiles/Suman_Nag","researchInterest":"Mutations in the beta-cardiac myosin (a molecular motor) cause disastrous effects by manifestation of hypertrophic and dilated cardiomyopathy, a leading cause of cardiac death. We hypothesize that the such mutations cause fundamental mechanistic changes in the motor which in turn affect the efficiency of the motor in several ways. My current research involves single molecule enzyme kinetics and force measurements to link intrinsic changes in motor function to the various clinical outcomes."},{"lastName":"Kaiser","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4522&type=small&showNoImage","displayName":"A Dale Kaiser","firstName":"A","href":"http://med.stanford.edu/profiles/A_Kaiser","researchInterest":"How are genes regulated to construct a developmental program?  How do signals received from other cells change the program and coordinate it for multicellular development?  The approach taken by our laboratory group to answer these questions utilizes biochemistry and genetics; genetics to isolate mutants that have particular defects in development and biochemistry to determine the molecular basis of the defects. We study swarming  in Myxococcus xanthus that builds fruiting bodies."},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Shukla","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23493&type=small&showNoImage","displayName":"Diwakar Shukla","firstName":"Diwakar","href":"http://med.stanford.edu/profiles/Diwakar_Shukla","researchInterest":""},{"lastName":"Doniach","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8062&type=small&showNoImage","displayName":"Sebastian Doniach","firstName":"Sebastian","href":"http://med.stanford.edu/profiles/Sebastian_Doniach","researchInterest":""},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8138&type=small&showNoImage","displayName":"Ted Jardetzky","firstName":"Theodore","href":"http://med.stanford.edu/profiles/Theodore_Jardetzky","researchInterest":"The Jardetzky laboratory is studying the structures and mechanisms of macromolecular complexes important in viral pathogenesis, allergic hypersensitivities and the regulation of cellular growth and differentiation, with an interest in uncovering novel conceptual approaches to intervening in disease processes.  Ongoing research projects include studies of paramyxovirus and herpesvirus entry mechanisms, IgE-receptor structure and function and TGF-beta ligand signaling pathways."},{"lastName":"Winans","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20077&type=small&showNoImage","displayName":"Amy Winans","firstName":"Amy","href":"http://med.stanford.edu/profiles/Amy_Winans","researchInterest":""},{"lastName":"Tsetsenis","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10368&type=small&showNoImage","displayName":"Theodoros Tsetsenis","firstName":"Theodoros","href":"http://med.stanford.edu/profiles/Theodoros_Tsetsenis","researchInterest":""},{"lastName":"Solomon","clinicalFocus":[],"appointments":[{"appointment":"Professor,Natural Sciences Cluster - Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Photon Science Directorate"}],"primaryAppointment":"Professor,Natural Sciences Cluster - Chemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8081&type=small&showNoImage","displayName":"Edward I. Solomon","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Solomon","researchInterest":"Professor Solomon\u0092s research is in the fields of Physical-Inorganic, Bioinorganic, and Theoretical-Inorganic Chemistry. His focus is on spectroscopic elucidation of the electronic structure of transition metal complexes and its contribution to reactivity.  He has made significant contributions to our understanding of metal sites involved in electron transfer, copper sites involved in O2 binding, activation and reduction to water, and in structure/function correlations over non-heme iron enzymes."},{"lastName":"Kruse","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Structural Biology"}],"primaryAppointment":"Ph.D., Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20137&type=small&showNoImage","displayName":"Andrew Kruse","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Kruse","researchInterest":""},{"lastName":"Feng","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35054&type=small&showNoImage","displayName":"Liang Feng","firstName":"Liang","href":"http://med.stanford.edu/profiles/Liang_Feng","researchInterest":"We are interested in the structure, dynamics and function of eukaryotic transport proteins mediating ions and major nutrients crossing the membrane, the kinetics and regulation of transport processes, the catalytic mechanism of membrane embedded enzymes and the development of small molecule modulators based on the structure and function of membrane proteins."},{"lastName":"Maloney","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Neurology & Neurological Sciences"}],"primaryAppointment":"Basic Life Science Research Associate,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9199&type=small&showNoImage","displayName":"Michael Maloney","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Maloney","researchInterest":""},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Engr Res Assoc,Genetics"}],"primaryAppointment":"Engr Res Assoc,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9027&type=small&showNoImage","displayName":"Tianyun Liu","firstName":"Tianyun","href":"http://med.stanford.edu/profiles/Tianyun_Liu","researchInterest":""},{"lastName":"Janda","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10499&type=small&showNoImage","displayName":"Claudia Janda","firstName":"Claudia","href":"http://med.stanford.edu/profiles/Claudia_Janda","researchInterest":""},{"lastName":"Covy","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24766&type=small&showNoImage","displayName":"Jason C.","firstName":"Jason","href":"http://med.stanford.edu/profiles/Jason_Covy","researchInterest":""},{"lastName":"Ko","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10414&type=small&showNoImage","displayName":"Rose Ko","firstName":"Rose","href":"http://med.stanford.edu/profiles/Rose_Ko","researchInterest":""},{"lastName":"Olivares","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18321&type=small&showNoImage","displayName":"Gonzalo Olivares","firstName":"Gonzalo","href":"http://med.stanford.edu/profiles/Gonzalo_Olivares","researchInterest":"Stem cells are unique in that can renew themselves through cell division or differentiate into a diverse range of specialized cell types.  I will study genes that functions to prevent the growth of tumors and regulates stem cell decisions. Understanding the molecular mechanisms that mediate the choice between self-renewal and differentiation in stem cells has important implications for many areas of biology, including ancer treatment, regenerative medicine and new cell-based therapies."},{"lastName":"Guiton","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=33260&type=small&showNoImage","displayName":"Pascale Guiton","firstName":"Pascale","href":"http://med.stanford.edu/profiles/Pascale_Guiton","researchInterest":"How do sporozoites, the product of sexual reproduction of Toxoplasma, co-opt host cell functions to initiate an infection in a new intermediate host? [Sporozoites express a very different arsenal of secreted proteins many of which are expected to serve as \"effectors\" that alter host cell function in ways beneficial to the invading parasite.]"},{"lastName":"Murphy","clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"},{"focus":"Neuropsychiatry"},{"focus":"Dementia"},{"focus":"Mood Disorders"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","displayName":"Greer Murphy M.D., Ph.D.","firstName":"Greer","href":"http://med.stanford.edu/profiles/Greer_Murphy","researchInterest":"Pharmacogenetics of mood disorders and nicotine addiction.  Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease."}]}