{"result":[{"lastName":"Block","clinicalFocus":[],"appointments":[{"appointment":"Professor,Natural Sciences Cluster - Applied Physics"},{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Natural Sciences Cluster - Applied Physics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6209&type=small&showNoImage","displayName":"Steven M. Block","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Block","researchInterest":""},{"lastName":"Campbell","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6212&type=small&showNoImage","displayName":"Allan Campbell","firstName":"Allan","href":"http://med.stanford.edu/profiles/Allan_Campbell","researchInterest":""},{"lastName":"Hodges","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15813&type=small&showNoImage","displayName":"Courtney Hodges","firstName":"Hamilton Courtney","href":"http://med.stanford.edu/profiles/Hamilton Courtney_Hodges","researchInterest":""},{"lastName":"Doniach","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8062&type=small&showNoImage","displayName":"Sebastian Doniach","firstName":"Sebastian","href":"http://med.stanford.edu/profiles/Sebastian_Doniach","researchInterest":""},{"lastName":"Bryant","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Structural Biology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8004&type=small&showNoImage","displayName":"Zev Bryant","firstName":"Zev","href":"http://med.stanford.edu/profiles/Zev_Bryant","researchInterest":"Molecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work."},{"lastName":"Smolke","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Bioengineering"}],"primaryAppointment":"Associate Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11013&type=small&showNoImage","displayName":"Christina Smolke","firstName":"Christina","href":"http://med.stanford.edu/profiles/Christina_Smolke","researchInterest":""},{"lastName":"Kornberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4308&type=small&showNoImage","displayName":"Roger Kornberg","firstName":"Roger","href":"http://med.stanford.edu/profiles/Roger_Kornberg","researchInterest":"We study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells"},{"lastName":"Larson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36392&type=small&showNoImage","displayName":"Timothy Larson","firstName":"Timothy","href":"http://med.stanford.edu/profiles/Timothy_Larson","researchInterest":""},{"lastName":"Frank","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8065&type=small&showNoImage","displayName":"Curtis Frank","firstName":"Curtis","href":"http://med.stanford.edu/profiles/Curtis_Frank","researchInterest":""},{"lastName":"Yanofsky","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","displayName":"Charles Yanofsky","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Yanofsky","researchInterest":""},{"lastName":"Pu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23603&type=small&showNoImage","displayName":"Kanyi Pu","firstName":"Kanyi","href":"http://med.stanford.edu/profiles/Kanyi_Pu","researchInterest":""},{"lastName":"Ohlson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9289&type=small&showNoImage","displayName":"Maikke Ohlson","firstName":"Maikke","href":"http://med.stanford.edu/profiles/Maikke_Ohlson","researchInterest":""},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7014&type=small&showNoImage","displayName":"Kendric C. Smith","firstName":"Kendric","href":"http://med.stanford.edu/profiles/Kendric_Smith","researchInterest":"The photochemistry and radiation chemistry of DNA, the genetic control and biochemical bases of the multiple pathways of DNA repair, and the roles of DNA repair processes in radiation and spontaneous mutagenesis. Over 190 papers have been published on these and related topics."},{"lastName":"St-Pierre","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12492&type=small&showNoImage","displayName":"Francois St-Pierre","firstName":"Francois","href":"http://med.stanford.edu/profiles/Francois_St-Pierre","researchInterest":""},{"lastName":"Tang","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24676&type=small&showNoImage","displayName":"Sindy Tang","firstName":"Sindy","href":"http://med.stanford.edu/profiles/Sindy_Tang","researchInterest":""},{"lastName":"Hanawalt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Dermatology"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","displayName":"Philip C. Hanawalt","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Hanawalt","researchInterest":"Our current research focuses in two principal areas:\r\n\r\n1. The molecular basis for  diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight  but  get no cancers. See Hanawalt & Spivak, 2008, for review.\r\n\r\n2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks."},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor,Microbiology & Immunology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10429&type=small&showNoImage","displayName":"KC Huang","firstName":"Kerwyn","href":"http://med.stanford.edu/profiles/Kerwyn_Huang","researchInterest":""},{"lastName":"Turner","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Ph.D., Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19577&type=small&showNoImage","displayName":"Jonathan Turner","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Turner","researchInterest":""},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","displayName":"Oleg Jardetzky","firstName":"Oleg","href":"http://med.stanford.edu/profiles/Oleg_Jardetzky","researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure"},{"lastName":"Maeda","clinicalFocus":[{"focus":"Hematology/Oncology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Hematology"},{"appointment":"Clinical Assistant Professor,Medicine - Oncology"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15802&type=small&showNoImage","displayName":"Lauren Maeda","firstName":"Lauren","href":"http://med.stanford.edu/profiles/Lauren_Maeda","researchInterest":""},{"lastName":"Das","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biochemistry"}],"primaryAppointment":"Assistant Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10421&type=small&showNoImage","displayName":"Rhiju Das","firstName":"Rhiju","href":"http://med.stanford.edu/profiles/Rhiju_Das","researchInterest":"Rhiju Das strives to predict how sequence codes for structure in proteins, nucleic acids, and heteropolymers whose folds have yet to be explored. The Das group uses new computational and experimental tools to tackle the de novo modeling of protein and RNA folds, the high-throughput structure mapping of riboswitches and random RNAs, and the design of self-knotting and self-crystallizing nucleic acids."},{"lastName":"Nag","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23884&type=small&showNoImage","displayName":"Suman Nag","firstName":"Suman","href":"http://med.stanford.edu/profiles/Suman_Nag","researchInterest":"Mutations in the beta-cardiac myosin (a molecular motor) cause disastrous effects by manifestation of hypertrophic and dilated cardiomyopathy, a leading cause of cardiac death. We hypothesize that the such mutations cause fundamental mechanistic changes in the motor which in turn affect the efficiency of the motor in several ways. My current research involves single molecule enzyme kinetics and force measurements to link intrinsic changes in motor function to the various clinical outcomes."},{"lastName":"Schrader","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24231&type=small&showNoImage","displayName":"Jared Schrader","firstName":"Jared","href":"http://med.stanford.edu/profiles/Jared_Schrader","researchInterest":""},{"lastName":"Williams","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Natural Sciences Cluster"}],"primaryAppointment":"Postdoctoral Research fellow, Natural Sciences Cluster","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13524&type=small&showNoImage","displayName":"James Williams","firstName":"James","href":"http://med.stanford.edu/profiles/James_Williams","researchInterest":""},{"lastName":"Cha","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Materials Science and Engineering"}],"primaryAppointment":"Postdoctoral Research fellow, Materials Science and Engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13272&type=small&showNoImage","displayName":"Jeeyoung Cha","firstName":"Jeeyoung","href":"http://med.stanford.edu/profiles/Jeeyoung_Cha","researchInterest":""}]}