{"result":[{"lastName":"Ruiz-Lozano","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Pediatrics - Cardiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Pediatrics - Cardiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18359&type=small&showNoImage","displayName":"Pilar Ruiz-Lozano, Ph.D.","firstName":"Pilar","href":"http://med.stanford.edu/profiles/Pilar_Ruiz-Lozano","researchInterest":"Cardiac development and repair"},{"lastName":"Ashley","clinicalFocus":[{"focus":"Cardiology"},{"focus":"Inherited cardiovascular disease"},{"focus":"Heart Failure"},{"focus":"Genomic medicine"},{"focus":"Hypertrophic Cardiomyopathy"},{"focus":"Cardiomyopathy, Dilated"},{"focus":"Arrhythmogenic Right Ventricular Dysplasia"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7578&type=small&showNoImage","displayName":"Euan A. Ashley","firstName":"Euan","href":"http://med.stanford.edu/profiles/Euan_Ashley","researchInterest":"The Ashley lab is focused on the application of genomics to medicine. We develop methods for the interpretation of whole genome sequencing data to improve diagnosis of genetic disease and to personalize the practice of medicine. We also use RNA sequencing data to generate gene networks and link communities. Half of the lab is wet benches where we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality of our favorite targets."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Mochly-Rosen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","displayName":"Daria Mochly-Rosen","firstName":"Daria","href":"http://med.stanford.edu/profiles/Daria_Mochly-Rosen","researchInterest":"Two areas:  1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling.  We focus on protein kinase C (PKC)-mediated signal transduction and on mitochondrial dynamics in several disease models. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, we study their involvement  in normal cells and in models of human diseases."},{"lastName":"Xu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17499&type=small&showNoImage","displayName":"Shi-Ming Xu, Ph.D.","firstName":"Shi Ming","href":"http://med.stanford.edu/profiles/Shi Ming_Xu","researchInterest":"The cardioactive peptide apelin has been shown to improve insulin sensitivity systemically. however, its effects on cardiac metabolism are unknown.My current research interests are to uncover the role of apelin and its downstream signaling intermediates in the pathogenesis of diabetic cardiomyopathy."},{"lastName":"Teruel","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14171&type=small&showNoImage","displayName":"Mary Frances Nunez Teruel","firstName":"Mary","href":"http://med.stanford.edu/profiles/Mary_Teruel","researchInterest":"The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity."},{"lastName":"Liao","clinicalFocus":[],"appointments":[{"appointment":"Visiting Associate Professor,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Visiting Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=33861&type=small&showNoImage","displayName":"Xiaobo Liao","firstName":"Xiaobo","href":"http://med.stanford.edu/profiles/Xiaobo_Liao","researchInterest":""},{"lastName":"Clusin","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"},{"focus":"Electrocardiography"}],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4502&type=small&showNoImage","displayName":"William Clusin, MD","firstName":"William","href":"http://med.stanford.edu/profiles/William_Clusin","researchInterest":"Cardiac action potentials; tissue culture, voltage, clamp technique; role of calcium in ischemia arrhythmias; coronary, artery disease; myocardial infarction."},{"lastName":"Tsao","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Cardiovascular Medicine"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4070&type=small&showNoImage","displayName":"Philip S. Tsao, PhD","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Tsao","researchInterest":"Our primary interests are in the molecular underpinnings of vascular disease as well as assessing disease risk.  In addition to targeted investigation of specific signaling molecules, we utilize global genomic analysis to identify gene expression networks and regulatory units.  We are particularly interested in the role of microRNAs in gene expression pathways associated with disease."},{"lastName":"Dash","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8685&type=small&showNoImage","displayName":"Rajesh Dash, MD, PhD","firstName":"Rajesh","href":"http://med.stanford.edu/profiles/Rajesh_Dash","researchInterest":"My research focuses on imaging cell signaling in the heart.  I am developing molecular imaging probes that  track to injured heart tissue, such that non-invasive imaging techniques, like cardiac MRI, can visualize these probe signals in real-time.  The translational goal of my research is to develop new ways to detect early cardiac injury before permanent damage occurs, so that preventive medical therapy can be started."},{"lastName":"Yue","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8441&type=small&showNoImage","displayName":"Patrick Yue","firstName":"Patrick","href":"http://med.stanford.edu/profiles/Patrick_Yue","researchInterest":"My primary research focus has been the mechanisms of insulin resistance and diabetes as they pertain to the heart.  I am particularly interested in the potential involvement of the recently discovered peptide hormone apelin.  Recent studies in my laboratory group have focused on apelin's role in promoting insulin sensitivity on the systemic, tissue-specific, and cellular level.  We are currently investigating apelin-mediated signaling events in insulin-sensitive and -resistant cardiac muscle."},{"lastName":"Spin","clinicalFocus":[{"focus":"Aortic Disease"},{"focus":"Marfan Syndrome and Aortic Disorders"},{"focus":"Cardiovascular Disease"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Clinical Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6448&type=small&showNoImage","displayName":"Joshua M. Spin","firstName":"Joshua","href":"http://med.stanford.edu/profiles/Joshua_Spin","researchInterest":"Dr. Spin began his research career studying the structural biology of low density lipoprotein, and has been augmenting his skills with intensive training in molecular biology techniques, particularly those involving high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development and vascular disease. His latest work has focused on the biology of aortic aneurysms."},{"lastName":"Hou","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Cardiovascular Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Cardiovascular Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=38380&type=small&showNoImage","displayName":"Luqia Hou","firstName":"Luqia","href":"http://med.stanford.edu/profiles/Luqia_Hou","researchInterest":""},{"lastName":"Desai","clinicalFocus":[{"focus":"Pediatric Cardiology"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5909&type=small&showNoImage","displayName":"Kavin Desai","firstName":"Kavin","href":"http://med.stanford.edu/profiles/Kavin_Desai","researchInterest":""},{"lastName":"Wu","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34047&type=small&showNoImage","displayName":"Sean M. Wu","firstName":"Ming","href":"http://med.stanford.edu/profiles/Ming_Wu","researchInterest":"My lab seeks to identify mechanisms regulating cardiac lineage commitment during embryonic development and the biology of cardiac progenitor cells in development and disease. We believe that by understanding the transcriptional and epigenetic basis of cardiomyocyte growth and differentiation, we can identify the most effective ways to repair diseased adult hearts. We employ mouse and human embryonic and induced pluripotent stem cells as well as rodents as our in vivo models for investigation."},{"lastName":"Stoeckius","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37530&type=small&showNoImage","displayName":"Marlon Stoeckius","firstName":"Marlon","href":"http://med.stanford.edu/profiles/Marlon_Stoeckius","researchInterest":""},{"lastName":"Leeper","clinicalFocus":[{"focus":"Vascular Medicine"},{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Surgery - Vascular Surgery"},{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Surgery - Vascular Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9669&type=small&showNoImage","displayName":"Nicholas Leeper","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_Leeper","researchInterest":""},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during repair and regeneration after tissue injury."},{"lastName":"Mukai","clinicalFocus":[],"appointments":[{"appointment":"Visiting Assistant Professor,Pathology"}],"primaryAppointment":"Visiting Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14756&type=small&showNoImage","displayName":"Kaori Mukai","firstName":"Kaori","href":"http://med.stanford.edu/profiles/Kaori_Mukai","researchInterest":""},{"lastName":"Galli","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4374&type=small&showNoImage","displayName":"Stephen Galli","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Galli","researchInterest":"The goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and the expression of mast cell and basophil function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/Ching-Pin_Chang","researchInterest":"The ultimate goal of my laboratory is to define the molecular mechanisms underlying cardiovascular development and disease and translate the bench findings to clinical applications. One objective is to understand how the major types of cardiac cells (endocardial, myocardial, epicardial and neural crest cells) interact with each other to generate heart tissues. We are interested in chromatin regulation, transcriptional and signaling events that coordinate their interactions and assembly into hea"},{"lastName":"Sylvester","clinicalFocus":[{"focus":"Surgery, Pediatric"},{"focus":"Pediatric Surgery"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor - Med Center Line,Pediatrics"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3827&type=small&showNoImage","displayName":"Karl Sylvester","firstName":"Karl","href":"http://med.stanford.edu/profiles/Karl_Sylvester","researchInterest":"Current research interests include mesenchymal stem cell biology, clonal isolation of mesenchymal progenitors, signaling pathways for maintenance of potency and committment to differentiation.\r\n\r\nAdditional areas of ongoing study are the mechanisms of liver regeneration.  Interests include local and humoral cellular components of liver repair and regrowth; and the requisite cellular signaling mechanisms of liver stem cell biology."},{"lastName":"Malmersjoe","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15963&type=small&showNoImage","displayName":"Seth Malmersjö","firstName":"Carl","href":"http://med.stanford.edu/profiles/Carl_Malmersjoe","researchInterest":""},{"lastName":"Burridge","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23495&type=small&showNoImage","displayName":"Paul Burridge","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Burridge","researchInterest":"Cardiac differentiation of human induced pluripotent stem cells using developmental biology paradigms, chemically defined reprogramming, culture, and differentiation, disease modeling, cardiotoxicity, electrophysiology"}]}