{"result":[{"lastName":"Vanni","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37642&type=small&showNoImage","displayName":"Emilia Vanni","firstName":"Emilia","href":"http://med.stanford.edu/profiles/Emilia_Vanni","researchInterest":""},{"lastName":"Mocarski","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4146&type=small&showNoImage","displayName":"Edward Mocarski","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Mocarski","researchInterest":"My research interests focus on the biology and pathogenesis of cytomegalovirus (CMV), an opportunistic pathogen that causes significant disease worldwide. We developed global approaches and produced key insights into the areas of CMV gene regulation, DNA replication and packaging, maturation, impact on the host cell, disease pathogenesis, latency and reactivation, host cell signaling and chemokine system. These diverse findings address key aspects of the virus-host interaction."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stanford Cancer Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15254&type=small&showNoImage","displayName":"Cleo Lee","firstName":"Cleo Yi-Fang","href":"http://med.stanford.edu/profiles/Cleo Yi-Fang_Lee","researchInterest":"My current research interests are to study the biology of breast cancer stem cells (CSCs) and the functional role of genes involved in CSCs proliferation and self-renewal. Since CSCs are believed to be responsible for recurrent and metastatic breast cancer, the ultimate goal is to develope targeted therapies to specifically kill the CSCs subpopulation. Identification of genes involved in CSCs functions may lead to novel CSC targeted therapy."},{"lastName":"Cimprich","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Chemistry"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4417&type=small&showNoImage","displayName":"Karlene Cimprich","firstName":"Karlene","href":"http://med.stanford.edu/profiles/Karlene_Cimprich","researchInterest":"The use of genetic, biochemical and chemical approaches to understand the DNA damage-induced cell cycle checkpoints and the processes that contribute to maintenance of genomic stability."},{"lastName":"Lin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19977&type=small&showNoImage","displayName":"Jia-Ren Lin","firstName":"Jia-Ren","href":"http://med.stanford.edu/profiles/Jia-Ren_Lin","researchInterest":""},{"lastName":"Mitra","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=38012&type=small&showNoImage","displayName":"Siddhartha Mitra","firstName":"Siddhartha","href":"http://med.stanford.edu/profiles/Siddhartha_Mitra","researchInterest":""},{"lastName":"Driscoll","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8819&type=small&showNoImage","displayName":"Robert Driscoll","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Driscoll","researchInterest":""},{"lastName":"Jarosz","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor,Developmental Biology"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=33778&type=small&showNoImage","displayName":"Daniel Jarosz","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Jarosz","researchInterest":"Survival in changing environments requires the acquisition of new heritable traits. However, mechanisms that safeguard the fidelity of DNA replication often limit the source of such novelty to relatively modest changes in the genetic code. Thus, the acquisition of new forms and functions is thought to be driven by rare variants that occur at random, and are enriched during times of stress. We have begun to study an intriguing alternative hypothesis: that intrinsic links between protein folding "},{"lastName":"Kopito","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6227&type=small&showNoImage","displayName":"Ron Kopito","firstName":"Ron","href":"http://med.stanford.edu/profiles/Ron_Kopito","researchInterest":"Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells.  We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins."},{"lastName":"Khalil","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36421&type=small&showNoImage","displayName":"Mohamed Khalil","firstName":"Mohamed","href":"http://med.stanford.edu/profiles/Mohamed_Khalil","researchInterest":""},{"lastName":"Bhalla","clinicalFocus":[{"focus":"Nephrology"},{"focus":"Nephrology (Kidney)"},{"focus":"Diabtetic Kidney Disease"},{"focus":"Hypertension"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Nephrology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8442&type=small&showNoImage","displayName":"Vivek Bhalla, MD","firstName":"Vivek","href":"http://med.stanford.edu/profiles/Vivek_Bhalla","researchInterest":"Dr. Bhalla's research interests are in the pathogenesis of diabetic kidney disease and salt-sensitive hypertension. Using molecular and transgenic approaches, the laboratory is interested in elucidating regulators of oxidative and carbonyl stress in glomeruli. We interface these studies with collaborative projects on biomarkers for human diabetic nephropathy. \r\n\r\nThe laboratory also focuses on molecular mechanisms of insulin and aldosterone-induced sodium transport in the distal nephron."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Chu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15846&type=small&showNoImage","displayName":"Matthew Chu","firstName":"Ling Hon","href":"http://med.stanford.edu/profiles/Ling Hon_Chu","researchInterest":""},{"lastName":"Hanawalt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Dermatology"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","displayName":"Philip C. Hanawalt","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Hanawalt","researchInterest":"Our current research focuses in two principal areas:\r\n\r\n1. The molecular basis for  diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight  but  get no cancers. See Hanawalt & Spivak, 2008, for review.\r\n\r\n2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks."},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Chuang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=30560&type=small&showNoImage","displayName":"Chen-Hua Chuang","firstName":"Chen-Hua","href":"http://med.stanford.edu/profiles/Chen-Hua_Chuang","researchInterest":""},{"lastName":"Chu","clinicalFocus":[{"focus":"Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4149&type=small&showNoImage","displayName":"Gilbert Chu","firstName":"Gilbert","href":"http://med.stanford.edu/profiles/Gilbert_Chu","researchInterest":"Our laboratory focuses on understanding how cells respond to DNA damage. Our research currently involves areas that interact with each other: repair of radiation damage, and transcriptional responses to DNA damage."},{"lastName":"Maeda","clinicalFocus":[{"focus":"Hematology/Oncology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Hematology"},{"appointment":"Clinical Assistant Professor,Medicine - Oncology"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15802&type=small&showNoImage","displayName":"Lauren Maeda","firstName":"Lauren","href":"http://med.stanford.edu/profiles/Lauren_Maeda","researchInterest":""},{"lastName":"van Buuren","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=30879&type=small&showNoImage","displayName":"Nicholas van Buuren","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_van Buuren","researchInterest":"Using poliovirus as a model system, the Kirkegaard laboratory has developed a method to decrease the risk of drug-resistance during RNA virus antiviral therapy by targeting dominant drug targets.  My goal is to identify equivalent dominant drug targets in hepatitis C virus in order to decrease the risk of drug-resistance during hepatitis C virus antiviral therapy."},{"lastName":"Jackson","clinicalFocus":[],"appointments":[{"appointment":"Acting Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Acting Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4463&type=small&showNoImage","displayName":"Peter Jackson","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Jackson","researchInterest":"Cell cycle and cyclin control of DNA replication ."},{"lastName":"Okerlund","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24767&type=small&showNoImage","displayName":"Nathan Okerlund","firstName":"Nathan","href":"http://med.stanford.edu/profiles/Nathan_Okerlund","researchInterest":""},{"lastName":"Mendoza","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29257&type=small&showNoImage","displayName":"Juan L. Mendoza","firstName":"Juan","href":"http://med.stanford.edu/profiles/Juan_Mendoza","researchInterest":""},{"lastName":"Crasta","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10372&type=small&showNoImage","displayName":"Sheela Crasta","firstName":"Sheela","href":"http://med.stanford.edu/profiles/Sheela_Crasta","researchInterest":""},{"lastName":"Chung","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Obstetrics & Gynecology"}],"primaryAppointment":"Basic Life Science Research Associate,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10387&type=small&showNoImage","displayName":"Young Min Chung","firstName":"Young Min","href":"http://med.stanford.edu/profiles/Young Min_Chung","researchInterest":""}]}